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Biomedical subjects

J B Henry

Publications and source records attributed to J B Henry.

At least 37 records · Page 2Linked to original sources
PubMed1987

Evaluation of coagulation disorders in patients with diseases of Waldeyer's ring.

The presence of pre-existing hemostatic disorders in a surgical patient may pose difficulties in the care of patients during and after surgery. To reduce the risk of excessive hemorrhage, this article has stressed the value of a thorough medical history, physical examination, and appropriate laboratory assays before surgery. When these measures reveal no evidence of a coagulation disorder, the surgeon can have confidence that the patient's hemostatic system has the appropriate resources to prevent excessive bleeding during surgery. However, if the coagulation screening procedure suggests that an abnormality exists, specific diagnostic assays must be performed before any necessary surgery to determine the exact nature of the coagulopathy. When this information is present, specific forms of blood component therapy can be given to minimize the risk of excessive hemorrhage during the operative period.

Adenoidectomy↗
PubMed1987

The effect of changing technology on manpower in pathology and laboratory medicine.

This article reviews changes in technology, the economics of reimbursement, and the health care delivery system and describes the cumulative impact of these trends on pathologists, pathologists-in-training, and pathology laboratories. While an increase in the number of pathologists-in-training is not anticipated, their training will be influenced by the new biology of medicine and emerging new technologies. Specialized preparation of graduate medical education trainees will create new opportunities for pathologists, enabling them to respond to new challenges associated with change. Those who also hold degrees in management will be prepared to assume leadership roles.

Laboratories↗
PubMed1981

Impact of high tuition on medical school applicants and enrollees.

As direct federal support of medical education has been reduced, tuition at U.S. medical schools has increased. Concern has been expressed over a decline in the socioeconomic diversity and the academic qualifications of the applicants. Experience gained at Georgetown University School of Medicine, the medical school with the highest tuition in the United States, indicates that the academic and nonacademic characteristics of the entering class have remained stable over a seven-year period despite a fourfold increase in tuition. Virtually all (98 percent) enrolled students currently receive some form of financial aid, mostly in the form of federally insured loans or federal scholarships with a service commitment. Maintenance of socioeconomic diversity depends on the continued availability of federally supported student loans and scholarships.

College Admission Test↗
PubMed1981

HLA antigens and childhood acute lymphocytic leukaemia.

HLA-A and -B antigens were determined for 94 children with acute lymphocytic leukaemia (ALL) and for 376 normal controls. Sixty-four of these 94 patients were typed for lymphocyte surface markers and 59 were defined as 'null cell' ALL. There was no difference in the distribution of the HLA-A or -B locus antigens between the control group and the entire group of patients with ALL or the 'null cell' subgroup. Patients with HLA-A9 determinants had a significant increase in early, first remission duration compared to patients without HLA-A9. This was particularly evident in the 'null cell' ALL subgroup. In addition, HLA-A9 appeared to be an independent factor affecting the length of first remission since there was no correlation between known prognostic factors such as patient age, sex or WBC and the presence or absence of the HLA-A9 antigen. Survival for the first 12-18 months was also greater in the HLA-A9 group than in the non-HLA-A9 population. Thus, the presence of HLA-A9 appears to be associated with some protective effect among patients with ALL.

Adolescent↗
PubMed1980

Estimation of the postmortem interval by chemical means.

The literature is reviewed regarding estimation of the postmortem interval (PMI) by chemical analysis of cadaver fluids. The most useful measurements on blood and CSF are amino nitrogen, nonprotein nitrogen, ammonia, creatine, and inorganic phosphate; these have some value in the early PMI. Probably the single most accurate determination is the potassium content of the vitreous humor, which shows a linear rise with time in the interval 12-100 hours postmortem. The rate of vitreous potassium rise is fairly independent of environmental influence. Other determinations that may prove valuable include the potassium content of the aqueous humor and the ammonia and magnesium content of the vitreous. Although no single measurement gives a completely reliable estimate of the PMI, combinations of chemical determinations can be useful adjuncts in cases of unwitnessed death.

Ammonia↗
PubMed1980

Regional enteritis: evidence for genetic transmission by HLA typing.

Lymphocytes from kindreds containing five sibling pairs affected with regional enteritis were typed to ascertain the association between histocompatibility leukocyte antigens (HLA)-A and -B and regional enteritis. Also, the frequency of HLA antigens in 22 patients with nonfamilial cases of regional enteritis was compared to the frequency in 402 normal blood donors. No HLA haplotype was found in more than one kindred, and no HLA antigen was more prevalent in nonfamilial cases of regional enteritis than in the normal population. In the five affected sibling pairs, four shared both haplotypes (HLA identical), and one shared one haplotype. Only one unaffected sibling shared two haplotypes with an affected proband. The high frequency of HLA identity in affected siblings and the low frequency of identity in unaffected siblings suggest linkage between the histocompatibility locus and the development of regional enteritis. There appears to be a genetic component in kindreds with regional enteritis.

Chromosome Mapping↗
PubMed1980

Regional associations: recent changes in blood services.

In this article, the authors describe the American Blood Commission's organizational and operational model of blood service regionalization, applied through the ABC's Regionalization Program. Explained are the criteria by which regional associations can obtain ABC "recognition," which acknowledges status as an approved regional association of blood service units.

Blood Banks↗