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Biomedical subjects

J Anthony

Publications and source records attributed to J Anthony.

At least 91 records · Page 5Linked to original sources
PubMed1983

Ultrastructure of skin in erythema nodosum leprosum.

The ultrastructural changes observed in erythema nodosum leprosum lesions were gross damage to blood vessels, particularly the endothelial cells, and deposition of immune complexes in vessel walls. Infiltrating cells and alteration of the ground substance formed a constant feature of the reaction. These changes are characteristic of an immune complex reaction.

Blood Vessels↗
PubMed1980

[Review of French literature on Latimeria, notably since 1972].

French research on Latimeria published before 1972 is first briefly recalled. After the Anglo-Franco-American Expedition of 1972, the material obtained enabled us to focus attention on the histology of the kidney and ureter and on ultrastructural aspects of the postnatal gland. Ovarian eggs of unusual volume have been collected, measured and weighed. Kinematic analysis of the intracranial articulation was carried out in 1973 on a frozen coelacanth that reached Paris. Studies in 1974 of a 41 cm specimen, the smallest known at that time and estimated to be 3 1/2 years old, showed that the brain still filled the cranial cavity: thus, it is later that allometric growth of the cranial cavity relegates the brain to the posterior part of the skull. In the same specimen, radiographed after injection with colloidal barium oxide, we were able to specify the likely role of the contractile organs fused to the branchial arteries: they may serve to regulate arterial pressure in the head during sudden movements of the jaws, and thus of the anterior cranium, as prey is captured. Lastly, the structural characteristics of the teeth, scale denticles, and spines on the lepidotrichia have been revealed, as also has the lamellar structure of the scales, in which there is a crossed orientation of the fibres in the different layers.

Animals↗
PubMed1979

Histologic study of the regeneration of axillary hair after removal with subcutaneous tissue shaver.

It was observed that after subcutaneous tissue shaving for the radical therapy of hircismus and hyperhidrosis axillary hair often regrew. Histologic study of this phenomenon showed that hair bulb and most of the follicle up to a level near the sebaceous duct opening had been removed. Hair regrows from remnant outer root sheath, but only when sebaceous glands are preserved, that is when the upper portion of the follicular isthmus is intact. One or several solid epithelial pegs grow downward from the cut end of the trichilemma, and inner root sheath and new young hair are formed in its center. In hair peg stage, the lower tip of the hair follicle descends while new hair is growing in its center through the mitotic activity is growing in its center through the mitotic activity of hair germ cells and is prevented from pushing toward the skin surface by interlocking fusion between hair cuticula and sheath cuticula. Eventually, the epithelial cells wrap around a mass of mesenchymal cells and form a new bulb from which the terminal hair grows upward. The new matrix acquires a new complement of functioning melanocytes.

Adult↗
PubMed1979

Ultrastructure of nerve in erythema nodosum leprosum (ENL).

Gross changes of myelinated fibres and Schwann cells at different degenerative stages were present in all five ENL nerve lesions. Besides these changes, infiltrating cells mainly macrophages, deposition of excessive collagen and perineurial vessel damage were also observed.

Blood Cells↗
PubMed1978

Radical operation to stop axillary odor and hyperhidrosis.

We have developed a subcutaneous tissue shaver for the radical treatment of hircismus and hyperhidrosis. With this shaver the sweat glands can be removed from the undersurface of the axillary skin through a small incision. We report 3,000 cases of hircismus and hyperhidrosis treated by our method. The postoperative scar has been minimal, healing has been quick, and good results were achieved by this method.

Axilla↗
PubMed1978

Regeneration of axillary hair and related phenomena after removal of deep dermal and subcutaneous tissue by a special "shaving" technique.

A subcutaneous tissue "shaver" was used in the treatment of axillary bromhidrosis. Regeneration of axillary hair was observed postoperatively even if subcutaneous tissue and dermis were removed almost up to the level of sebaceous ducts. Hair regenerated more often in male patients whose sebaceous glands and follicular isthmus were designedly left intact than in female patients whose sebaceous glands were designedly removed completely. Some function of apocrine and eccrine glands tends to return over a two-year period.

Axilla↗
PubMed1978

Immunological methods employed in an attempt to induce erythema nodosum leprosum (ENL) in mice.

In the mouse foot pad model five different parameters were employed to simulate the condition of ENL as observed in the human. The experimental groups with five to six months leprosy infection were injected intravenously with various anti-mycobacterial antibodies, M. leprae sonicate and 'B' cells obtained from syngenic donors. The control group of animals, infected similarly, were treated either with M. leprae sonicate or gamma globulins precipitated from normal human serum. All recipients were killed at one day interval excepting those with 'B' cell transfer, which were sacrificed at seven days. The sites of predilection for immune complex deposition viz. foot pad and kidney as well as the spleen were examined by light and fluorescence microscopy. These findings are described and discussed.

Animals↗
PubMed1978

The Voiscope.

Explore the source record for details and available documents.

Deafness↗
PubMed1975

The development of a glucose clamp.

A reliable control system was developed for clamping (i.e., holding at a steady level) the concentration of blood glucose in the hyperglycemic region of a normal nonanesthetized dog. The system is based upon, and hence largely validates, a mathematical model of the canine glucoregulatory mechanism which was assembled from the results of experiments in which radioisotopes were used. The operation of the clamp, however, does not require the use of radioisotopes. The glucose clamp is a tool which may be applicable clinically in the measurement of glucose turnover and in the laboratory in the study of the effects of glucose turnover of variable insulin with constant glucose levels.

Animals↗
PubMed1975

Fibreoptic laryngoscopy in the assessment of laryngeal disorders.

The fibreoptic laryngoscope is described, and its method of use detailed. Seventy patients were submitted to this examination. Its advantages and disadvantages in the assessment of the various groups of laryngeal disorders in these patients are discussed and compared with indirect and direct laryngoscopy. Its teaching and research possibilities are also mentioned. The technique shows considerable promise and will, we believe, achieve an accepted place as an addition to our diagnostic armamentarium in the investigation of laryngeal disorders.

Adult↗