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Biomedical subjects

J Andrew

Publications and source records attributed to J Andrew.

At least 37 records · Page 2Linked to original sources
PubMed1982

Tremor after head injury and its treatment by stereotaxic surgery.

Tremor, both postural and kinetic may be a late complication for victims of severe closed head injury, especially in the young, and may add to their disability. The nature of the tremor is described in eight patients. In each a stereotaxic thalamotomy was performed, dramatically relieving or reducing the severity of tremor in each instance, and resulting in improved function of the affected limb and increased independence. The site of the responsible lesion, which is thought to lie in the mid brain, is discussed together with the indications and contraindications for surgical management.

Adolescent↗
PubMed1976

Infection of intervertebral discs after operation.

Infection of the intervertebral space is a rare complication of operation on the disc (Ford and Key 1955). It occurred in five cases in a series of 650 operations for lumbar disc protrusion done by two of the authors of this paper--an incidence of 0-8%. Symptoms began between seven and twelve days after operation. After initial relief of the original sciatic pain, the patients developed severe back pain and muscle cramps in the legs. Straight-leg raising became much more limited than before operation. The erythrocyte sedimentation rate was raised in all cases. The diagnosis was confirmed by rescreening the Myodil, when an indentation was seen opposite the intervertebral space from which the disc had been excised. Early removal of infected material from the disc space resulted in complete relief of pain and cure of the infection.

Adult↗
PubMedDate not supplied

Age-restricted cervical screening: HPV testing at age 50 identifies a high risk group for cervical disease.

Changes to the present age policy of cervical screening are currently under consideration. We conducted a retrospective matched case-control study and cost analysis study to identify risk factors for the development of an abnormal smear after age 50 and to determine the impact of age-restricted cervical screening on the annual cost of the screening program. All women (229) from an 11-year birth cohort who developed an abnormal smear at age 50 or over were age-matched for two controls with negative smears. Routine screening smears taken between age 48 and 52 were tested for human papillomavirus (HPV) subtypes 16 and 18. Epidemiologic data were collected by postal questionnaire. Changes in costs under a policy of HPV testing and age-restricted screening were assessed. We found that HPV 16 status was the only independently significant risk factor for abnormal cytology after age 50 with an odds ratio of 10.26 (95% CI 1.25-84.11). A policy of early withdrawal from screening at age 50 on the basis of HPV testing would produce net cost savings. These findings suggest that HPV testing could be a valuable means of identifying the small proportion of women still at risk after 50, and of releasing health care resources.

Age Factors↗