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Biomedical subjects

J Ahmad

Publications and source records attributed to J Ahmad.

51 records · Page 3Linked to original sources

Bisalbuminemia in nephrotic syndrome (a case report).

A rare case of bisalbuminemia in a patient with minimal lesion glomerulonephritis (MLGN) in which the course of the disease and therapeutic response to steroid were typical of minimal lesion glomerulonephritis, is presented and literature reviewed.

Child↗

Sampling, sampling errors and specimen preparation.

To obtain an adequate cervical smear for making a correct cytologic diagnosis, smear taking, laboratory handling and interpretation must be optimal. Many people are involved, and only by a combined effort of all links can this target be seriously approached: the smear takers will have to be open minded about technical improvements and read the morphologic descriptions cautiously; in the laboratory, cytotechnicians and physicians will have to challenge themselves and each other. It is mandatory to discard specimens that do not meet general standards of adequacy. At present a host of new techniques are being implemented. It is not feasible for all laboratories to be engaged in testing these new methods, but we are all requested to follow the development the best we can and switch to new ways when justified. Our working conditions are very different; therefore, it is our professional responsibility and plight to respond at the right time. So far the conclusion is that the conventional Pap smear is the international standard of care for the diagnosis of cervical cancer precursers in cancer screening programs. Certainly, this may change within a very short time. Liquid-based techniques, and in particular HPV technologies, are just around the corner.

Cell Biology↗

Protection against hemorrhagic enteritis and Newcastle disease in turkeys by embryo vaccination with monovalent and bivalent vaccines.

The feasibility of embryo vaccination against Hemorrhagic enteritis (HE) and Newcastle disease (ND) in specific-pathogen-free turkey embryos was studied. Turkey eggs were injected with marble spleen disease virus (MSDV) at embryonation day (ED) 24, and tissues of poults hatching from virus-injected eggs were examined for MSDV. The virus was detected in spleen, intestine, liver, and bursa between 4 to 10 days postinoculation (PI). The peak titer of MSDV was present in the spleen at 6 days PI. Poults hatching from eggs injected with MSDV produced antibodies to the virus and resisted a challenge with virulent hemorrhagic enteritis virus (HEV) at 4 weeks of age. The B1 strain of NDV (NDV-B1) injected in turkey eggs at ED 24 killed the embryos. NDV-B1 modified by treatment with ethylmethane sulfonate (NDV-B1-EMS) was not lethal for turkey embryos. Poults hatching from eggs injected at ED 24 with NDV-B1-EMS developed antibodies to NDV and were protected from challenge exposure with virulent NDV at 4 weeks of age. Poults from eggs inoculated at 24 ED with a bivalent vaccine containing MSDV and NDV-B1-EMS developed antibodies to both viruses and were resistant to challenge with both virulent viruses. The study showed that SPF turkeys may be immunized by in ovo injection of live viral vaccines.

Animals↗