Doctors disunited.
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Biomedical subjects
Publications and source records attributed to J Adno.
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A case of serologically proven symptomatic rubella re-infection in early pregnancy in a healthy multigravida who had been successfully vaccinated is reported to illustrate that the risk to the fetus is considerably less than with primary infection. The infant was infected, as evidenced by specific IgM in cord blood, but had no stigmata of congenital rubella at birth. Growth retardation was apparent at 6 months and hearing loss, not necessarily due to rubella, was detected at 8 months. Rubella re-infection, which may now be distinguished serologically by the urea degradation test from primary rubella, need not necessarily be an indication for termination of pregnancy.
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The effects of prophylactic tinidazole on the vaginal carrier state of anaerobic bacteria and the development of postoperative infections were studied in 50 patients undergoing gynaecological surgery. The results are based on a double-blind trial, using tinidazole (Fasigyn; Pfizer) and placebo. Although no postoperative infections other than urinary tract infections were observed in our series, this study shows conclusively that the isolation of anerobic bacteria from the vagina decreased markedly in the tinidazole group compared with the placebo group.
The successful treatment with levamisole of 3 categories of Herpesvirus hominis infection is described. A fourth category of patients infected with vulval condylomata acuminata were unsuccessfully treated with levamisole. The dosage regimen is discussed. The most dramatic feature was the relief of the severe pain encountered in the acute cases. Levamisole has also prevented further attacks to date. There is no doubt that levamisole has a definite place in the treatment of H. hominis infections.
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