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Biomedical subjects

J Abrahamson

Publications and source records attributed to J Abrahamson.

At least 55 records · Page 3Linked to original sources
PubMed1985

X-linked syndrome of branchial arch and other defects.

We report on two brothers and their maternal first cousin who have branchial arch defects and other anomalies. Similar physical findings in all three include microcephaly, downslanting palpebral fissures, highly arched palate, apparently lowset, protruding ears, bilateral hearing loss, slightly webbed neck, and mild short stature. In addition, two boys had cryptorchidism, and one had subvalvar pulmonic stenosis and body asymmetry. We suggest that these cousins have an X-linked syndrome of which branchial arch defects are a component. Other pleiotropic manifestations of the mutant gene include microcephaly and cryptorchidism; body asymmetry and relatively short stature may be components as well.

Abnormalities, Multiple↗
PubMed1984

Postoperative acute cholecystitis complicating urologic operations.

Two cases are described of acute gangrenous cholecystitis following urologic operations. The subject is reviewed. The predominance of urologic procedures as the preceding factor for this postoperative complication is pointed out. The possible causes, the presenting features, the diagnosis, management, and serious prognosis are discussed. Awareness of the condition, early diagnosis, and operation are recommended. Its importance to the urologist is stressed.

Acute Disease↗
PubMed1984

Neuropraxis secondary to hemorrhage in a traumatic dislocation of the shoulder.

A case of traumatic shoulder dislocation associated with a tear of the subscapular artery is presented. The main clinical feature was a dramatic neurologic loss of the brachial plexus, reversed by exploration, evacuation of hematoma, and ligation of the bleeding vessel. Early surgical decompression to achieve neurologic recovery is emphasized.

Aged↗
PubMed1984

Nonorganophilic, hematogenous dissemination in the presence of positive lymph nodes of a malignant tumor in rabbits.

An animal model has been devised which for the first time allows direct investigation of the roles of vascular dynamics, hematogenous versus lymphatic pathways, and involved regional lymph nodes in malignant dissemination. The VX2 anaplastic carcinoma growing in the hindlimb of rabbits normally metastasizes exclusively to the lungs, yet in this study was made to metastasize exclusively to the liver by construction of a cavoportal shunt prior to tumor transplantation. This technique also provided separation of the tumor's venous and lymphatic outflow. Normal and shunted animals with forelimb transplantation of the tumor, which acted as controls for the effects of the shunt operation itself, showed the same metastatic pattern as normal rabbits bearing hindlimb tumors. These results are direct evidence that a primary tumor metastasizes according to non-organophilic circulation dynamics and that lymphatic pathways, including metastatic regional lymph nodes, have no role in distant metastasis.

Animals↗
PubMed1983

Hydromediastinum and hydrothorax in the neonate with central vein catheterization.

A near fatal complication of central venous catheterization in a newborn infant is reported. Five days after insertion, the catheter tip eroded through the wall of the vein, causing hydromediastinum and hydrothorax with acute circulatory and respiratory distress. The diagnosis was confirmed by noting that the tip of the catheter had become curved downwards, by aspirating slightly bloodstained fluid from the pleural space and by injecting radio-opaque dye through the catheter. Recovery followed removal of the catheter, intercostal drainage, intubation and positive pressure respiration. The erosion of the vein may have been brought about by the location of the catheter tip at the junction of the left subclavian and innominate veins--a less than optimal position. The factors causing this complication are discussed. Recommendations are made about the type of catheter, its appropriate placement and maintenance. The diagnosis and management are surveyed.

Catheterization↗
PubMed1981

Spontaneous rupture of an abdominal aortic aneurysm into the inferior vena cava.

A 70-yr-old man developed acute localized and generalized symptoms and signs associated with a large aneurysm of the abdominal aorta. During an emergency operation, it was found that the aneurysm had ruptured into the inferior vena cava (IVC). The fistula was closed and the aneurysm replaced by a bifurcated synthetic graft. Important factors in the operative management were: clamping of the aorta above and the common iliac arteries below the aneurysm; opening of the aneurysm through a vertical incision; control of back bleeding through the fistula by external pressure on the IVC; closure of the fistula by a continuous braided dacron suture incorporating the walls of the aneurysm and the IVC; and replacement of the aneurysm by a bifurcated synthetic graft without excision of the aneurysm.

Aged↗