[Antabus is unsuitable in treatment of borderline personalities].
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Biomedical subjects
Publications and source records attributed to J Aberg.
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The "Back-Pain Institute" at Sundsvall offers an advanced rehabilitation program to people with long-standing back pain. This program has been evaluated in a controlled prospective study. Data were gathered from questionnaires mailed on three occasions, from the sick insurance office and from the bureau of employment. The effects of the Institute's course on the vocational situation were small. The only significant difference between the experimental group and the control group was in the level of income. Significantly more persons in the experimental group had begun to train their back and significantly more individuals in the experimental group believed that by using the correct working technique they could prevent back pain. No significant changes were found with regard to the subjective feeling of pain.
A new catheter for recording the urethral closure pressure profile (UCPP) in men and women in introduced. The measuring system utilizes perfusion and saline as a transmission medium. The dynamic response of the whole catheter system as a unit was studied in vitro, and profile studies of the female urethra were performed in vivo using a solid catheter equipped with micro-transducers as a reference. The small transmission volume and low-compliant perfusion gave a sufficient bandwidth for recordings of the UCPP. No significant difference was found in closing pressure and functional length in the UCPP of women between the new catheter and the solid catheter.
Experimental ischemia of 15, 30, or 60 min length, followed by 30 min of reperfusion, was produced in situ in the cat small intestine by means of an adjustable arterial clamp. Arterial perfusion pressure was lowered to such an extent that intestinal blood flow decreased from about 25 to 3.5 ml x min-1 x 100 g-1. The rate of free radical formation was followed intermittently with ESR and a modified spin trapping technique in the control period prior to ischemia and at various times during reperfusion. Upon reperfusion radical formation increased above the preischemic control value in all three series of experiments. Cumulative radical production during the 30 min reperfusion period rose from about 3 mumol x 100 g-1 after 15 min ischemia to approximately 4.5 mumol x 100 g-1 after 30 min and 8-10 mumol x 100 g-1 after 60 or 120 min ischemia. At the same time mucosal damage became more pronounced, suggesting a causal connection between tissue damage and radical formation. More specifically, radical production was strongly correlated to histological damage occurring during reperfusion as seen when comparing radical production in animals not experiencing reperfusion damage to those who did. Radical formation in these two groups were 0.35 and 9.0 mumol x 100 g-1, respectively (p < 0.0005).