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Biomedical subjects

J A Warren

Publications and source records attributed to J A Warren.

35 records · Page 2Linked to original sources
PubMed1983

Case report of carbamazepine-induced reticulocytes.

The authors present the case of a woman with bipolar disorder who developed reticulocytosis after two trials of carbamazepine. They urge that blood indices be carefully monitored whenever carbamazepine is used.

Adult↗
PubMed1977

Interaction between auditory and oral sensory feedback in speech regulation.

To investigate the interaction between the auditory and oral sensory feedback modalities during speech production lingual vibrotactile thresholds were obtained from subjects in the following conditions: (1) before and after speech production with normal auditory feedback, (2) before and after speech production under exposure to auditory masking, and (3) before and after exposure to auditory masking without performing speech tasks. In addition duration measurements were obtained for selected speech sounds to investigate temporal changes in the articulatory patterns of subjects in the various conditions. Lingual sensory decreases and temporal reorganization were observed only in subjects speaking under auditory masking. These data suggest a balanced interaction between auditory and oral sensory feedback modalities which, when disturbed, results in non-phonemic change in speech production.

Acoustic Stimulation↗
PubMed1970

Pathogenicity of Salmonella gallinarum after metabolic injury by freezing.

Freezing (-75 C) and storage (-20 C) of a cell suspension of Salmonella gallinarum resulted in a heterogeneous population of dead, metabolically injured, and unharmed cells. Injured cells constituted as much as 40% of those surviving freezing and storage for 1 day. Replica plating of frozen and thawed cells indicated metabolic injury was repairable and not a stable mutation. Penicillin was used to increase the ratio of injured to uninjured cells from a frozen and thawed cell suspension. Pathogenicity was evaluated by observing per cent mortality after injecting injured or uninjured cells into separate sets of chicks. Mortality differences between wholly uninjured and predominantly injured populations were small and consistent (5% level) with a hypothesis of no difference.

Animals↗
PubMed1968

Relief of casein inhibition of Bacillus stearothermophilus by iron, calcium, and magnesium.

Growth of Bacillus stearothermophilus strain NCA 1518 Smooth in Dextrose Tryptone Agar (DTA) was inhibited by sodium caseinate. Binding studies indicated that sodium caseinate, when present in DTA, had the capacity to effect an iron deficiency which could cause inhibition of growth. Additions of essential cations, iron (1 mM), calcium (5 mM), magnesium (10 mM), or hydrogen ion (pH 5.7), relieved inhibition. Responses to and interactions among these relief factors were analyzed statistically. Equations were fitted to the data and were used to estimate responses to all treatment combinations within the ranges tested. Results from these studies indicated that calcium, magnesium, and hydrogen ion acted by decreasing the binding capacity of the protein for iron, rendering this metal available for metabolic needs. Evidence was obtained that ferrous rather than ferric iron was the limiting factor in DTA containing sodium caseinate.

Analysis of Variance↗
PubMedDate not supplied

Portal to the community. Dedicating a facility to ambulatory and long-term care completes the continuum for a New Jersey system.

In 1989 Cathedral Healthcare System, Orange, NJ, began a strategic planning process that culminated in a decision to create a continuum of care. Converting one of its three hospitals from an acute care to an ambulatory care facility gave Cathedral an opportunity to address fiscal realities and at the same time further develop its continuum of care. The converted hospital (Saint Mary's in Orange) would be a key component of a full continuum of care for area residents. Saint Mary's would also serve as a portal of entry to the system's services. The community's need for affordable, accessible healthcare has been well documented. Converting Saint Mary's to alternative uses was one approach the system could take to better meet the needs of this underserved population. In addition to providing ambulatory care, Cathedral will be transforming the acute care beds into much-needed long-term care beds. The conversion will enable Saint Mary's to meet the needs of a growing aging population.

Ambulatory Care↗