Biomedical subjects

J A Stillman

Publications and source records attributed to J A Stillman.

11 recordsLinked to original sources

PubMed2003

Electrogustometry: strengths, weaknesses, and clinical evidence of stimulus boundaries.

Electrogustometry is well established as a clinical tool for the estimation of taste detection thresholds. Nevertheless, the user is sometimes unaware of the impact of superficially minor procedural and psychophysical factors upon the reliability and comparability of threshold estimates. The inherent strengths and limitations of the procedure are outlined, and aspects of the control and specification of the stimulus that moderate threshold measures are discussed. In addition, threshold estimates from two individuals with severe unilateral taste loss are used to illustrate the level at which anodal dc current may elicit common, rather than taste, sensation. Where chorda tympani section is complete and historical (older than 7-14 days), very high stimulus levels, conservatively over 5 micro A/mm2 (100 micro A linear current with a 5-mm diameter electrode), are required to activate trigeminal responses.

Adult↗

PubMed2000

Automated electrogustometry: a new paradigm for the estimation of taste detection thresholds.

Electrogustometery, first introduced in the 1950s for the clinical assessment of taste function, has returned to favour in recent years. This is due, in part, to the credence given to the procedure by an increased understanding of the mechanisms of taste transduction. The reliability and validity of electrogustometric assessments of taste function should increase with the use of automated testing. An automated computer-controlled testing paradigm was used to obtain threshold estimates simultaneously from the left and right sides of the tongue in 97 volunteers aged between 17 and 63 years. A small but statistically significant advantage was found for thresholds from the right side of the tongue (P<0.01). The range of thresholds, and of interside differences obtained with this procedure, are reported, and practical issues related to testing are discussed.

Adolescent↗

PubMed2000

Reliability of electrogustometry for the estimation of taste thresholds.

Electrogustometry has been used as a clinical tool for diagnosis and assessment of a variety of conditions. Several studies which have estimated electrogustometric taste threshold have reported good test-retest reliability but there is some evidence that thresholds measured this way may decrease with practice. In this study, repeated testing of the right and left sides of the tongue of two subjects over 80 sessions resulted in considerable session-to-session variability for both subjects, and three of the four sets of threshold estimates decreased systematically with continued testing. Two of the four data sets continued to show systematic decreases when the first 10 sessions were omitted from analysis to allow for any initial unfamiliarity with the testing procedure. This suggests that estimates based on few tests should be interpreted with caution, particularly when used for evaluation or monitoring of interventions.

Adult↗

PubMed2000

Influence of sensitivity on response bias in taste and audition.

A detection theoretic analysis was employed to examine sensitivity and response bias in two modalities. In Experiment 1, 6 tasters made same-different judgments about the concentration of either sucrose or quinine in pairs of tonic water samples. The beverages were colored, but color was not predictive of the concentration of the sweet or bitter ingredient. When same-different ratings were collapsed to approximate the outcome of a categorical decision, tasters with poorer sensitivity appear to have adopted more extreme response criteria than did tasters with greater sensitivity, irrespective of taste quality, color, or whether pairs of solutions comprised the same or different colors. In Experiment 2, 3 individuals discriminated pairs of 1000-Hz sinusoids differing in amplitude. Six amplitude differences were tested. Rating-scale versions of two paradigms: The single-interval yes-no task and the two-interval same-different task were used to measure sensitivity and bias. There was a preponderance of "same" responses in the same-different task. Estimates of bias obtained from collapsed ratings in both tasks were unaffected by sensitivity, but a consideration of the range over which sets of criteria were spread suggested a general tendency toward more conservative response biases as sensitivity declined.

Adult↗

PubMed1993

Intensity just-noticeable differences at equal-loudness levels in normal and pathological ears.

The relationship between loudness level and intensity discrimination was investigated in the frequency range 0.5-6.5 kHz by comparing the intensity just-noticeable differences (jnd's) at a number of equal-loudness levels in the better and poorer ears of eight individuals with essentially unilateral hearing loss of cochlear origin. Such hearing loss usually produces loudness recruitment, altering the relationships among the loudness, sound-pressure level (SPL), and sensation-level (SL) variables, so that their effects can be separated. In these experiments, the jnd's were correlated with loudness level, not SPL or SL. Although, in some listeners, there were significant differences between jnd's in the two ears at some binaurally equal-loudness levels, they were not systematic over the group of listeners. Statistically, there was no significant difference between equal-loudness jnd's in the two ears, whereas the corresponding SLs and SPLs were significantly different. The rate of loudness growth had no effect on the jnd's. As expected from the near-miss to Weber's law, the mean jnd's decreased with sound intensity. The corresponding decrease in the mean Weber fraction, delta I/I, was accompanied by a decrement in its intrasubject standard deviation. The latter was correlated with the mean, independent of its relationship to SPL or SL.

Acoustic Stimulation↗

PubMed1993

Response selection, sensitivity, and taste-test performance.

Tasters selected the odd stimulus from among sets of three samples of party dip. Two samples came from one batch, and one sample came from another batch. The physicochemical difference between the batches consisted of the presence or absence of added salt. Two different tests of discriminability were undertaken by the same subjects with the same stimuli: the triangle test and the three-alternative forced-choice (3-AFC) method. Although different numbers of correct selections were obtained in the two tasks, an index of discriminability, d', had the same value when the data were analyzed in accordance with the Thurstone-Ura and signal-detection models, respectively. The average data support Frijters's (1979b) contention that different models of the discrimination process are appropriate to the results of the triangular and the 3-AFC procedures. Further analysis of the data revealed that discrimination was poorer for trios containing one physicochemically weak stimulus and two stronger stimuli than it was for trios containing one stronger stimulus and two weak stimuli. A two-signal 3-AFC task was undertaken by some subjects, and d' estimates from this task were lower than expected on the basis of performance in the other tasks.

Adult↗

PubMed1993

Context effects in judging taste intensity: a comparison of variable line and category rating methods.

The effect of stimulus range and stimulus spacing was examined when subjects registered the perceived intensity of sweet liquids using either a matching procedure (Experiment 1) or category rating (Experiment 2). The matching procedure is conceptually similar to absolute magnitude estimation, whereby subjects match their impression of number size to their impression of the subjective magnitude of a stimulus. In Experiment 1, subjects matched their impression of the stimulus to their impression of the magnitude of the length of a continuously variable line under their control. In Experiment 2, subjects rated perceived sweetness on a vertical 13-point scale with five equally spaced verbal labels. In both experiments, three sets of four sucrose concentrations were employed. In two of these sets, a set of weaker solutions and a set of stronger solutions, concentrations were separated by 0.25 log units. In a third set, which spanned the range of concentrations used in the other two sets (0.87 to 27.36% w/v), solutions were separated by 0.5 log units. An examination of both individual and group data showed the matching procedure to be less susceptible to a range bias than the rating procedure. In particular, a single intensity function accommodated data from individual ranges better when the matching procedure was used than when the rating procedure was used. No effect of stimulus spacing was evident in the data from either procedure.

Attention↗

PubMed1990

Signal detectability in the presence of monotic or dichotic noise bands of equal or unequal levels.

The application of the power-spectrum model of masking to the detectability of a signal masked by dichotic noise was investigated in three experiments. In each experiment, the signal was a 2-kHz sinusoid of 400-msec duration, masked by either one or two 800-Hz wide bands of noise presented singly or in pairs. In Experiment 1, we compared the detectability of a diotic signal masked by dichotic noise with the detectability of a monaural signal masked by each of the noises separately. The spectrum level of the noise was 35 dB SPL. For dichotic presentations, the signal was sent to both ears while pairs of noise bands, one below and one above the signal frequency, were presented together, one band to each ear. Threshold levels with the dichotic stimuli were lower than or equal to the thresholds with either ear's stimulus on its own. Similar dichotic stimuli were used in Experiment 2, except that the signal frequency was nearer to one or the other of the bands of masking noise, and the noise had a spectrum level of 50 dB SPL. In Experiment 3, thresholds were obtained with two sets of symmetrically and asymmetrically placed notched-noise maskers. For one of these sets, the spectrum level of both noise bands was 35 dB SPL; for the other set, interaural intensity differences were introduced in the form of an inequality in the levels of the noise bands on either side of the signal. In one ear, the spectrum level of the lower frequency noise band was 35 dB SPL and the spectrum level of the higher frequency noise band was 25 dB SPL, whereas in the other ear, the allocation of noise level to noise band was reversed. The dichotic thresholds obtained with the unequal noise maskers could be predicted from the shapes of the auditory filters derived with equal noise maskers. The data from all three experiments suggest that threshold signal levels in the presence of interaural differences in masker intensity depend principally on the ear with the higher signal-to-masker ratio at the output of its auditory filter, a finding consistent with the power-spectrum model of masking.

Adult↗

PubMed1989

A comparison of three adaptive psychophysical procedures using inexperienced listeners.

Thresholds for a masked 1-kHz tone were obtained in single sessions from 60 inexperienced listeners. A two-alternative forced-choice procedure was used in conjunction with one of three adaptive psychophysical techniques. These techniques comprised two staircase techniques targeting either 70.7% or 79.4% correct detection (Staircase-71 and Staircase-79), and parameter estimation by sequential testing (PEST), targeting 80% correct detection. Listeners were provided with a rationale for maintaining concentration at weak signal levels. Similar threshold values were obtained from the Staircase-79 and PEST groups in equal numbers of trials. The degree of oscillation in the level of the signal around the value finally chosen as the threshold was comparable for both staircase techniques. Subsequent fixed-level testing did not provide a true indication of the subjects' capabilities. The amount by which percent correct in fixed-level testing differed from expectations based on adaptive testing varied among the techniques. Additional thresholds were obtained in a second session from 30 of the original subjects. Thresholds with both staircase techniques improved by about 1 dB on retest, while thresholds with PEST were constant across sessions. The variability of the data compared well with that from studies involving experienced listeners.

Adult↗

PubMed1986

The width of the auditory filter in children.

Because young children have poorer auditory temporal resolution than older children, they ought to have, according to the inverse relation between temporal and frequency resolution, narrower auditory filters than older children. Therefore, the auditory filters of two 6-year-olds, two 10-year-olds, and two adults were measured by having them detect a 400-ms sinusoid (500, 1000, or 3000 Hz) centered in a spectral notch in a band of noise. The signal power for 71% correct was determined as a function of notch width with the two-alternative, forced-choice procedure. The principal results showed a significant decrease in signal power with age and a significant interaction between age and notch width. The best-fitting parameters of a model of the auditory filter showed that the filter was significantly wider for the 6-year-olds than for the 10-year-olds or the adults.

Adult↗

PubMed1985

The development of auditory temporal acuity in children.

The development of auditory temporal acuity was studied in 56 children aged 6-12 years and compared with that of 8 adults. Acuity was measured by determining the minimum detectable duration of a brief cessation in a noise band with the 2-alternative forced-choice method. For detection of gaps in a broadband noise, acuity improved significantly with age and reached adult values by 11 years. The minimum detectable duration was significantly shorter at higher levels of the noise. For narrow-band noises, acuity also improved significantly with age and depended on the center frequency of the band. The improvement in temporal acuity with age was attributed to the development of sensory processes and not to age-related changes in nonsensory factors.

Adult↗