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Biomedical subjects

J A Raymakers

Publications and source records attributed to J A Raymakers.

44 records · Page 3Linked to original sources

Calculation of three hours calcium absorption from a double isotope test; a simplified method.

For the rapid evaluation of calcium absorption in human subjects several isotopic tests have been proposed. Among them, the double isotope test based on the concurrent oral and intravenous administration of calcium isotopes seems the most reliable. However, the computations involved in this test, a deconvolution of the two specific-activity functions obtained, are quite extensive. By simulating these functions we developed a simple formula to calculate the absorption in the first three hours of the test. Applied to the data of 79 patients the result differed less than the experimental error from the absorption computed with the more elaborate deconvolution method.

Calcium↗

Pre-operative localization of parathyroid adenomas or parathyroid hyperplasia by means of venous sampling.

Pre-operative localization of parathyroid tumours on primary hyperparathyroidism is discussed. 20 patients were examined in this way. Of the 15 patients who were operated on, the pre-operative findings of 12 correspond with the results of operations and histological examinations. These results correspond with what is known from other publications. Preoperative localization by means of venous sampling is possible in a large number of cases. The examination is especially important in patients with previous neck exploration.

Adenoma↗

Effect of oral calcium and vitamin D on glucocorticoid-induced osteopenia.

Bone-loss in glucocorticoid-induced osteopenia is most evident in trabecular bone such as the vertebrae. Bone mineral content (BMC) measurements of the spine were prospectively studied, comparing the preventive effect of calcium (500 mg a day) and calcium plus Vitamin D (4000 IU on alternate days) during long-term corticosteroid treatment. A small increase in BMC was noted in both groups, but no differences between preventive calcium and calcium plus Vitamin D became evident. It is suggested that patients who are receiving prednisone should be advised to use supplemental calcium.

Administration, Oral↗