Search PubMed⌕ Search

Biomedical subjects

J A Pinkerton

Publications and source records attributed to J A Pinkerton.

14 recordsLinked to original sources
PubMed1979

Surgical treatment of renovascular hypertension.

The evaluation of patients with inadequate control of diastolic blood pressure for surgically correctable forms of hypertension led to the detection and surgical treatment of 56 patients. Detection was facilitated by the use of hypertensive intravenous pyelography and Hippuran renal Scanning. Aortography proved the presence of renal artery disease and renal vein renin assay established its significance in the etiology of the patients' hypertension. Renal artery reconstruction was performed in 50 patients, including 5 who also had reconstruction of major aortoiliac lesions. The extent of renal artery disease precluded arterial reconstruction in six patients, who required nephrectomy. Two postoperative deaths occurred, for a mortality rate of 3.6 per cent. Improvement in mean diastolic blood pressure for the total group of patients from 118 mm Hg preoperatively to 86 mm Hg postoperatively was achieved. Forty-six patients (85 per cent) have a diastolic blood pressure of 90 mm Hg or less; in 5 patients the diastolic blood pressure is 91 to 100 mm Hg but is at least 20 mm Hg lower than the preorative level.

Adult↗
PubMed1979

Intraoperative Doppler localization of intestinal arteriovenous malformation.

Arteriovenous malformations of the gastrointestinal tract have been identified as the cause of significant bleeding when other causes are obscure. A method of precise intraoperative localization using Doppler ultrasound technique is presented. The value of this method is shown in the management of an illustrative case of a rare arteriovenous malformation of the duodenum.

Aged↗
PubMed1979

Intestinal vascular malformations.

Eleven patients with intestinal vascular malformations (VMs), all diagnosed by angiography, are presented. Two of the VMs were incidental findings in patients treated for other problems; the other nine patients all presented with gastrointestinal hemorrhage, and all had resection of the portion of intestine containing the VM. None has rebled. The specimens from these nine patients revealed a variety of histological findings. One VM was the vasculature of small bowel leiomyoma. Three other specimens contained obvious VMs without associated findings, and one specimen contained no identifiable pathology. In the remaining four specimens, a variety of inflammatory conditions were found on histological study, including one case of Crohn's disease and another of ischemic colitis. In only one of these specimens did we identify the VM. None of these last four cases conforms to the degenerative lesions described by Boley and his colleagues. Therefore, we propose a fourth type of VM that is associated with or perhaps secondary to another disease of the intestine. We precisely localized one VM in the duodenum during operation with the Doppler ultrasonic flow detector, thus enabling us to limit the extent of the resection. We also propose the use of this technique for pinpointing the area where sections should be made for histological study.

Adult↗
PubMed1977

Traumatic aneurysm of the intrathoracic left carotid artery with cerebral embolization.

The presentation and management of a young male patient with a traumatic aneurysm of the intrathoracic portion of the left common carotid artery from a football injury, complicated by cerebral embolization, is detailed. At operation 6 weeks afterward the aneurysm was isolated and ligated and the patient was discharged 19 days postoperation with plans for physical and speech rehabilitation. At 14 months a chronic subdural hematoma which caused some seizures was removed, and the patient's neurologic status is continuing to improve. This appears to be the first report of an isolated blunt injury to this branch of the aortic arch.

Adult↗
PubMed1976

Fibrodysplasia with dissecting aneurysm of the hepatic artery.

The presentation and management of a patient with a symptomatic hepatic artery aneurysm is detailed. The aneurysm occurred secondary to fibromuscular hyperplasia of the hepatic artery and was associated with a limited area of dissection. This patient represents the second reported case of this type of aneurysm of the hepatic artery,

Aneurysm↗
PubMed1975

Operative arteriography. A new variation.

A technique of intraoperative arteriography for evaluating the technical construction of femoral popliteal bypass involves dierect injection of contrast material into the vein graft after construction of the distal anastomosis. This allows full assessment of the anastomosis and of graft position prior to transection of the graft or proximal femoral arteriotomy.

Angiography↗
PubMed1975

The use of monofilament suture in vascular surgery.

The blood lost through the suture line holes of vessels closed with braided polyester sutures is compared with that lost when a monofilament polypropylene suture is employed. In a retrospective analysis of blood replacement during saphenous vein aortorenal bypasses, twice as much blood replacement was required when the braided polyester suture was used. Further, ten dogs had one femoral artery reanastomosed with braided polyester suture and the other with monofilament polypropylene. Bleeding was three times greater and lasted six times longer when the braided polyester suture material was utilized.

Animals↗
PubMed1975

Hepatic resection and gastric secretion.

These experiments serve to deny the theory that abnormal liver function in the remaining liver tissue after 60-70 per cent hepatic resection might result in gastric acid hypersecretion as a result of a "physiologic shunting" of histamine or other gastric secretagogues.

Alkaline Phosphatase↗
PubMedDate not supplied

Erosion of Dacron graft by atherosclerotic plaque.

Erosion of a Dacron prosthetic graft used in aortic reconstruction following the intrasaccular resection of an infrarenal abdominal aneurysm resulted in perforation of the graft and the formation of a false aneurysm which ruptured. The pathogenesis and prevention of this problem are discussed.

Aged↗