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Biomedical subjects

J A Long

Publications and source records attributed to J A Long.

At least 55 records · Page 3Linked to original sources
PubMed1982

CT findings in Addison's disease.

The computed tomographic findings in five patients with depleted adrenal cortical reserve were evaluated. A single patient with idiopathic adrenal atrophy revealed small adrenal remnants bilaterally. Three patients with tuberculosis demonstrated dense calcification in one or both adrenal beds without evidence of normal glandular remnants. On patient and active histoplasmosis showed enlarged nonhomogeneous glands of normal contour, a possible clue in distinguishing acute granulomatous adrenalitis from primary or secondary intraadrenal tumors.

Addison Disease↗
PubMed1981

Radiographic contribution to diagnosis and treatment of complications from peritoneoscopy.

Peritoneoscopy is a valuable nonsurgical procedure for evaluating patients with malignant disease. Directed biopsies of suspected tumor masses may be obtained, and peritoneoscopy can frequently obviate the need for laparotomy. Although the complication rate is low, the radiologist must be aware of potential problems. Radiologists may participate not only in the diagnosis and localization of these complications but also in their therapy by interventional techniques. The radiographic findings in four patients with complications of peritoneoscopy are presented.

Adult↗
PubMed1981

Hepatocellular adenoma in a young woman with beta-thalassemia and secondary iron overload.

The occurrence of a hepatocellular adenoma is described in a young woman with beta-thalassemia and secondary iron overload. This patient had no history of oral contraceptive use, and in fact was hypogonadal as a result of iron deposition in pituitary and gonadal tissue. Although hepatocellular carcinoma frequently occurs in diseases associated with iron overload, this is the first report of a benign liver tumor associated with secondary iron overload.

Adolescent↗
PubMed1980

Computed tomographic analysis of beta-thalassemic syndromes with hemochromatosis: pathologic findings with clinical and laboratory correlations.

The major clinical problem in patients with thalassemia is iron overloading usually resulting from increased exogenous iron absorption from transfusions. Diseases of various organ systems result, including cirrhosis, cardiomyopathy, diabetes, and other less well appreciated endocrinopathies. Since 1976, we have routinely studied these patients with abdominal computed tomography (CT) and also have scanned other areas of clinical interest. It is the purpose of this report to examine the findings in 35 patients with severe beta-thalassemia and associated hemochromatosis in whom we have tabulated the pertinent CT, clinical and laboratory data.

Adolescent↗
PubMed1980

Cerebral mass lesions in torulosis demonstrated by computed tomography.

Cryptococcus neoformans is an ubiquitous yeast. As a budding type of fungus, it is also known as Torula histolytica and is a common cause of infection of the central nervous system (CNS), particularly in debilitated and immunodeficient patients. We have examined 12 patients with computed tomography who had well documented cryptococcal CNS infection and will review our findings in this paper. Three of these patients had mass lesions, while nine others had a variety of changes such as ventricular dilatation, cortical atrophy, and focal ischemic changes.

Adolescent↗
PubMed1980

Doppler monitoring of arterial punctures.

The authors describe a simple ultrasonic technique for monitoring arterial patency of the limb distal to the site of the arterial catheterization as well as the heart rate. The same system may be used to guide the puncture in obese patients and monitor patency of the artery while applying pressure with a clamp following catheter removal. This technique has been used in 800 patients over a three-year period with no untoward complications.

Angiography↗
PubMed1980

False aneurysm formation following arteriographic intimal dissection: serial studies in 2 patients.

Two patients with metastatic islet-cell carcinoma underwent multiple hepatic artery catheterizations for streptozotocin infusion. An intimal flap was raised during one of the initial arteriographic procedures and a false aneurysm developed. The progression of the aneurysm was documented on sequential studies. False aneurysm formation appears to be a relatively unappreciated complication of intimal dissection, and these 2 cases permitted observation of their natural history.

Adenoma, Islet Cell↗
PubMed1980

Localizing insulinomas with combined radiographic methods.

Twenty-one patients with hyperinsulinism were studied to localize the source of the insulin production. Nineteen patients had pancreatic tumors and two patients studied after pancreatectomy had hepatic metastases. Of the 19 pancreatic tumors, 16 were identified by angiography. CT found six tumors in 14 patients studied while sonography correctly localized only three of 12 tumors. Neither CT nor sonography was positive in those patients with a negative arteriogram. Noninvasive imaging methods can localize large tumors and may be useful for detecting hepatic metastases. Angiography, however, remains the most accurate method for detecting smaller lesions.

Adenoma, Islet Cell↗
PubMed1979

Keeping up-to-date: some current surgical and radiologic procedures.

Surgical advances often call for close radiologic scrutiny to assess their success or complications. At the same time, diagnostic radiology is also constantly developing new approaches. It is for this reason that we describe the radiographic analysis of several current surgical and radiological procedures which should be of interest to the practicing clinician. The current surgical procedures considered are gastric bypass for morbid obesity and continent ileostomy. The current new radiologic procedures include techniques for performing small bowel enema, per-oral ileal and colonic examinations with retrograde air insufflation, and improved evaluation of the postantrectomy stomach using double-contrast techniques.

Barium Sulfate↗
PubMed1979

Noninflammatory gas formation following embolization of adrenal carcinoma.

Gas formation as a result of transcatheter tumor embolization has recently been observed by conventional radiography. We report the computed tomography identification of similar benign gas formation following transcatheter embolization of a large adrenal carcinoma. Computed tomography should be the most sensitive method available for detecting gas formation. It is important to recognize this gas formation as a consequence of embolization and cell necrosis rather than as an indication of an inflammatory complication.

Adrenal Gland Neoplasms↗
PubMed1977

Ultrastructural changes induced by ACTH in normal adrenocortical cells in culture.

The effects of ACTH, its o-nitrophenyl sulfenyl derivative (NPS-ACTH) and dibutyryl cyclic AMP (dbc AMP) on the ultrastructural morphology of adrenocortical cells of adult rats in monolayer culture have been investigated. NPS-ACTH, which has previously been shown to stimulate steroidogenesis but not cAMP synthesis in adrenal cells, induced the same characteristic transformation of mitochondrial architecture as produced by ACTH or high concentrations of dbcAMP. All three agents caused the disappearance of electron-opaque granules present in the mitochondria of unstimulated cells. It was found that these granules could be extracted with EGTA (ethylene glycol-bis(beta-aminoethyl ether) N,N,N',N'-tetraacetate). These results are discussed in the light of the known importance of calcium ions in the actions of ACTH.

Adrenal Cortex↗