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Biomedical subjects

J A Lawrence

Publications and source records attributed to J A Lawrence.

83 records · Page 5Linked to original sources
PubMed1977

The globule leucocyte in bovine schistosomiasis.

Globule leucocytes were detected in forestomachs, abomasum, duodenum, ileum, large intestine, lung, liver, bladder and kidney in cattle infected with Schistosoma mattheei. In animals examined seven and eight weeks after infection they were found only in the lungs. They were present in the alimentary tract from 18 weeks onwards. They were most numerous and most widely distributed in animals subjected to repeated, heavy infection. There was evidence that they were associated with the immune response of the host and that they were derived from mast cells.

Abomasum↗
PubMedDate not supplied

Recovery of pure red-cell aplasia secondary to antierythropoietin antibodies after cessation of recombinant human erythropoietin.

We describe a patient with end-stage renal failure (ESRF) who developed anti-erythropoietin (anti-EPO) antibodies and pure red-cell aplasia (PRCA) after using Eprex (Janssen-Cilag, Sydney). Anti-EPO antibodies were detected with an immunoprecipitation technique and were shown to inhibit erythropoiesis in vitro. Antibody levels waned upon ceasing Eprex. The patient required transfusions for 21 months then recovered after immunosuppression.

Autoantibodies↗
PubMedDate not supplied

The effect of hyperbaric oxygen treatment on postural stability and gait of a brain injured patient: single case study.

Hyperbaric oxygen (HBO) therapy has been found to reduce intracranial and cerebrospinal fluid pressures, and increase grey matter metabolic activity in patients with brain injuries. To date, few studies have quantitatively assessed the changes in the patient's functional outcomes following this expensive therapeutic intervention. The purpose of this case study was to examine the immediate and longer term changes in postural stability and gait in a 17 year old patient who sustained a traumatic brain injury, following administration of hyperbaric oxygen (HBO) therapy combined with physical and occupational therapy. The patient underwent assessments of postural stability and gait 1 week prior to HBO therapy, immediately following, and 6 weeks after completion of HBO therapy. Some improvements in postural stability were observed immediately following HBO, although these improvements were not evident 6 weeks later. Only slight improvements were noted in his walking abilities immediately following the intervention, with essentially little change evident 6 weeks later. The results of this do not support anecdotal evidence that there were substantial improvements in the subject's postural stability and gait following HBO therapy.

Adolescent↗