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Biomedical subjects

J A Harolds

Publications and source records attributed to J A Harolds.

At least 19 recordsLinked to original sources
PubMed1999

18-Fluorodeoxyglucose imaging in oncology.

This article describes the use of 18-fluorodeoxyglucose (FDG) scans for the diagnostic evaluation of cancer patients. Since FDG is a positron emitting radio-pharmaceutical, a dedicated Positron Emission Tomography unit (PET) or a hybrid PET/SPECT (single photon emission computed tomography) unit is required for oncologic studies. As PET and PET/SPECT scanners become available to perform these images, it is important that knowledge regarding the usefulness of these images, and their limitations, be disseminated to health care providers. There are evolving uses of FDG scans; current use includes staging patients with non-small cell carcinoma of the lung, malignant melanoma, Hodgkin's disease, non-Hodgkin's lymphoma, colorectal carcinoma, and head and neck carcinoma.

Biophysical Phenomena↗
PubMed1998

Correlation of gallbladder ejection fraction with pathologic grade for chronic inflammation.

BACKGROUND: The purpose of this study is to define the sensitivity and specificity of the gallbladder ejection fraction (GBEF) for identifying patients with various grades of histologically proven chronic cholecystitis. METHODS: Of 693 consecutive patients who had a scintigraphic GBEF determination at Baptist Medical Center of Oklahoma, 161 subsequently had a cholecystectomy at the same institution. Pathologic material was reassessed by one outside blinded reviewer, who graded the intensity of the inflammation present on a 0 (absent) to 3 (most severe) scale. RESULTS: The least square mean maximum GBEF was 23.7% for those with grade 0, 9.6% for those with grade 3, and 13.9% for those with cholesterolosis. If a normal value for GBEF is set at > 30%, the sensitivity for detecting grade 1, 2, or 3 disease was 84%, and the specificity was 26%. For grade 3 disease alone, the sensitivity was 100%, and the specificity was 26%. CONCLUSIONS: The GBEF is sensitive but not specific for chronic inflammation of the gallbladder. The GBEF appears to be useful as a screening examination in the appropriate clinical setting.

Cholecystitis↗
PubMed1996

Technetium-99m-albumin colloid lymphoscintigraphy in postoperative lymphocele.

An important use of lymphoscintigraphy is to evaluate extremity edema. Lymphoscintigraphy has many advantages over contrast lymphangiography in these patients. We report an unusual case of lymphocele of the left upper chest wall which was discovered incidentally during lymphoscintigraphic evaluation of left upper arm edema. This lymphocele was due to prior surgery, but in some patients the etiology is previous trauma or idiopathology.

Aged↗
PubMed1993

Stereotactically guided needle biopsy of the breast for nonpalpable lesions.

Stereotactically guided needle biopsy of the breast is a new diagnostic technique in this country to obtain samples of a nonpalpable area deemed suspicious for malignancy on mammography. This article is a review of the literature, a report of a case, and a description of the technique. This procedure, when performed with a large core biopsy needle, appears to be about as accurate as surgical biopsy.

Biopsy, Needle↗
PubMed1983

Comparison of supine, upright, and prone positions for liver scans.

We compared liver scan interpretations based on anterior images obtained in the upright, prone, and supine positions. Receiver-operating-characteristic curves were generated for three well trained observers. Results showed that reading the three different views together was more accurate than the reading of any individual image. Furthermore, interpretations based on either the prone or upright view were superior to those using the supine view alone. The prone and upright views should be used more often in liver scanning.

Humans↗
PubMed1983

Intratracheal neurofibroma.

We have described a unique example of intratracheal neurofibroma in a patient with neurofibromatosis. Although tracheal neoplasms are rare, they should be considered in the presence of obstructive respiratory symptoms. Careful scrutiny of plain roentgenograms with special views should be undertaken for optimal evaluation.

Adolescent↗
PubMed1981

Fatigue fractures of the medial tibial plateau.

The effectiveness of a protocol for the detection of medial tibial plateau fatigue fractures using radiographs and delayed scintigraphs is evaluated. The high false-positive rate of early scanning generally requires delayed radiographs to make a definite diagnosis. If this lesion is suspected, however, early use of scans should be encouraged for several reasons, including the detection of occult but potentially more serious stress fractures elsewhere.

False Positive Reactions↗