Biomedical subjects

J A Gaillard

Publications and source records attributed to J A Gaillard.

31 records · Page 2Linked to original sources

PubMedDate not supplied

[An immunological technic (ABC immunoperoxidase) demonstrating hepatic differentiation in teratocarcinomas of the mouse].

The present work shows that hepatic tissue occasionally appears in certain mouse teratocarcinomas: the presence of hepatic structures in these tumours, suspected on the basis of routine histological examination, is confirmed here by the use of anti-mouse alpha-foetoprotein serum and the ABC immunoperoxidase technique.

Animals↗

PubMedDate not supplied

[Immunological localization of alpha-fetoprotein in the proximal endoderm and its significance in extra-embryonic differentiation of teratocarcinomas in the mouse].

The ABC technique using a specific anti-mouse alpha-foetoprotein (AFP) serum permits identification of groups of extraembryonic proximal endoderm cells in certain teratocarcinomas. These AFP+ cells are always associated with trophoblastic and parietal endodermal patterns and structures. These observations strongly support the hypothesis of a common precursor to the extraembryonic tissues which appears during the first phases of egg development.

Animals↗

PubMedDate not supplied

[Immunohistochemical localization of chorionic gonadotropin and alpha fetoprotein in polyembryomas: description and interpretation].

As polyembryomas are special forms of human teratomas in which numerous structures mimicking the early stages of the human embryo are conspicuous, immunoperoxidase staining of these embryoid bodies (EB) has been used to reveal the initial appearance and localization of beta HCG and AFP, respectively, in amnion and in primary yolk-sac. EB are involved in the building of various questionable patterns of teratomatous germ-cell tumours. Special emphasis has been placed on tracking yolk-sac tumour patterns through dislocating EB, using a specific anti-human AFP serum.

Antibodies, Monoclonal↗

PubMedDate not supplied

[Immunohistochemical localization of alpha-fetoprotein in the vitelline sac of a two-week old human embryo].

Histological sections of a stage 6b human embryo (13-15 days old) were immunohistochemically stained for specific alphafoetoprotein (AFP). Conspicuous AFP+ endodermal cells were observed in the yolk-sac wall using the ABC peroxidase technique, which gave consistent results on dismounted and decolorized old slides.

Gestational Age↗

PubMedDate not supplied