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Biomedical subjects

J A Fixsen

Publications and source records attributed to J A Fixsen.

65 records · Page 4Linked to original sources

Osteotomy of the lesser trochanter for rheumatoid arthritis of the hip.

Forty-eight operations of osteotomy of the lesser trochanter in 45 patients were reviewed after an average of three and a half years. Of 10 hips affected by proved rheumatoid arthritis eight obtained complete relief of pain and two partial relief. Of 38 hips affected by osteoarthritis 16 had complete relief and 17 partial relief.The results suggest that osteotomy of the lesser trochanter deserves a more extended trial in cases of proved rheumatoid arthritis of the hip joint.

Adult↗

Humeral rodding in osteogenesis imperfecta.

Seven patients with osteogenesis imperfecta who have undergone humeral rodding were reviewed. Satisfactory functional results were obtained in six of seven patients. We discuss the indications for surgery in our unit, the complications, and the results in comparison with those of other centres.

Adolescent↗

The orthopaedic presentation and management of Sjögren-Larsson syndrome.

Sjögren-Larsson syndrome is a rare autosomal recessive neurocutaneous disorder in which the combination of spasticity, ichthyosis, and mental retardation commonly result in patients being wheelchair bound. We reviewed a cohort of children with Sjögren-Larsson syndrome who were successfully managed with early physiotherapy and later soft-tissue surgery. The favourable outcome seen in these patients should encourage orthopaedic intervention in suitable cases.

Child↗

Thorn-induced granuloma of the medial cuneiform.

A lytic lesion of the medial cuneiform of a 10-year-old boy was explored surgically, and a date palm thorn was identified. Histology revealed an aseptic granuloma. Even in the absence of a definite history of trauma, an organic foreign body lesion should be considered in the differential diagnosis of a lytic lesion of bone.

Child↗

Muscular strength after callotasis limb lengthening.

Seven patients (average age, 9.2 years; range, 7.6-10.6 years) underwent collotasis lengthening of a congenital short femur. The isometric voluntary contraction strength of the knee extensor muscles was measured for each leg immediately before and at 6-month intervals for 2 years, starting from 2 months after the fixator was removed. The normal side was always stronger, even when strength was standardized for an anthropometric estimate of the thigh muscle and bone cross-sectional areas. The increase in strength was correlated with the increase in limb size, both in the normal and in the lengthened limb. Although leg length discrepancy was equalized by the end of the procedure, the functional characteristics of the lengthened limb remained impaired for a significant time.

Analysis of Variance↗

Investigation and management of the painful hip in childhood.

The cause of the painful hip in childhood must be identified quickly to avoid permanent damage resulting from conditions such as septic arthritis. A painful hip may be the presenting feature of a number of conditions and their investigation and management are described here.

Acute Disease↗

Septicemia in a child undergoing callotasis limb lengthening.

We report a patient undergoing femoral callotasis lengthening using the dynamic axial fixator to correct a post-infective leg length discrepancy of 7.8 cm. Seventeen days after the operation, the patient developed a pin site infection, which was successfully treated by oral antibiotics. On the 34th post-operative day, the infection reoccurred, and was accompanied by generalized malaise, vomiting and pyrexia. Serology identified Staphylococcus aureus enterotoxin. Following removal of the fixator, the child recovered, but only four cm of lengthening was achieved. The pins probably acted as a persistent foreign body, with local inflammation creating favorable ground for bacterial infection. The role of the previous multifocal osteomyelitis unclear, but it could have acted as a continuous source of pathogens. The resulting toxemia was not immediately suspected, and could have resulted in the loss of the patient had the fixator not been removed promptly.

Anti-Bacterial Agents↗