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Biomedical subjects

J A Finkelstein

Publications and source records attributed to J A Finkelstein.

At least 37 records · Page 2Linked to original sources

Self-reported physician practices for children with asthma: are national guidelines followed?

OBJECTIVE: To determine self-reported adherence to national asthma guidelines for children by primary care physicians in managed care; and, to analyze sources of variation in these practices by physician specialty and managed care practice type. DESIGN: A survey of 671 primary care physicians (pediatricians and family physicians) practicing in 3 geographically diverse managed care organizations (MCO). Domains of interest included asthma diagnosis, pharmacotherapy, patient education and follow-up, and indications for specialty referral. Item formats included self-reports of usual practice and responses to case vignettes. RESULTS: A total of 429 (64%) physicians returned surveys, 22 of whom did not meet criteria for inclusion in the analysis. Most respondents had both heard of (91%) and read (72%) the National Asthma Education and Prevention Program (NAEPP) guidelines. For diagnosis, 75% reported routine use of office peak flow measurement, but only 21% used spirometry routinely. Family physicians were more likely than pediatricians to use spirometry in diagnosis (odds ratio [OR] = 5.9), and less likely to recommend daily peak flow measurement (OR =.3). The median reported frequency of providing written care plans was only 50%. Though inhaled corticosteroids were deemed very safe or safe by 93%, almost half had specific concerns regarding at least 1 side effect, most commonly growth delay. Primary care physicians' criteria for referral to an asthma specialist differed from those of the NAEPP panel in choosing to manage more severe patients without asthma specialist input. Family physicians were more likely than pediatricians to refer a child after a single hospitalization, 2 to 3 emergency department visits, after 2 exacerbations, or if the child was <3 years old and required daily medications. Responses to vignettes showed generally appropriate initial use of antiinflammatory agents, but reluctance to increase the dose in response to continued symptoms, and less frequent follow-up than recommended by the NAEPP. CONCLUSION: Most physicians for children report having read and adopted NAEPP guideline recommendations for asthma treatment, including generally appropriate use of medications. Opportunities for improvement exist in specific areas such as the use of written care plans, optimizing antiinflammatory dosing, and providing routine follow-up. Although physicians show evidence of awareness of national guidelines and knowledge consistent with much of their content, additional work is required to promote the use of self-management tools in practice.

Administration, Inhalation↗

Effect of a reduced postpartum length of stay program on primary care services use by mothers and infants.

OBJECTIVE: To determine the impact of reduced postpartum length of stay (LOS) on primary care services use. METHODS. DESIGN: Retrospective quasiexperimental study, comparing 3 periods before and 1 period after introducing an intervention and adjusting for time trends. SETTING: A managed care plan. INTERVENTION: A reduced obstetrical LOS program (ROLOS), offering enhanced education and services. PARTICIPANTS: mother-infant dyads, delivered during 4 time periods: February through May 1992, 1993, and 1994, before ROLOS, and 1995, while ROLOS was in effect. INDEPENDENT MEASURES: Pre-ROLOS or the post-ROLOS year. OUTCOME MEASURES: Telephone calls, visits, and urgent care events during the first 3 weeks postpartum summed as total utilization events. RESULTS: Before ROLOS, LOS decreased gradually (from 51.6 to 44.3 hours) and after, sharply to 36.5 hours. Although primary care use did not increase before ROLOS, utilization for dyads increased during ROLOS. Before ROLOS, there were between 2.37 and 2.72 utilization events per day; after, there were 4.60. Well-child visits increased slightly to.98 visits per dyad, but urgent visits did not. CONCLUSION: This program resulted in shortened stays and more primary care use. There was no increase in infant urgent primary care utilization. Early discharge programs that incorporate and reimburse for enhanced ambulatory services may be safe for infants; these findings should not be extrapolated to mandatory reduced LOS initiatives without enhancement of care.

Adult↗

Workshop on taste and smell in the elderly: an overview.

The purpose of the workshop entitled Taste and Smell in the Elderly: Behavioral and Nutritional Consequences was 1) to review the current state of knowledge in the area of taste and smell, with emphasis on age-related changes, 2) to identify existing gaps in our knowledge, and 3) to develop future research strategies. There was general agreement that the majority of scientific studies have found impairments in taste and smell acuity in the elderly. These losses may result from normal aging, certain disease states especially Alzheimer's disease, medications, surgical interventions, and environmental exposure. However, there are gaps in our knowledge of the basic mechanisms by which aging and environmental factors may impair the chemical senses in the elderly. Further research is also required in a variety of areas including chemosensory test procedures, food intake, and nutrition to understand fully the impact of chemosensory dysfunction on older individuals.

Aged↗

Occult vertebral fractures in ankylosing spondylitis.

STUDY DESIGN: A retrospective review of patients with ankylosing spondylitis involved in a blunt trauma. SETTING: Patients referred to two Level I tra uma centers. OBJECTIVES: To determine the incidence and clinical sequelae in thi s patient population where vertebral injury was diagnosed on a delayed basis. SUMMARY OF BACKGROUND DATA: The ankylosed spine is at increased risk for fracture and spinal cord injury. Radiological identification of injury is more difficult than in the normal spine. RESULTS: Over a 5 year period, 21 patients were identified with seven having an occult vertebral fracture not recognized as the primary injury or occurring as a second non-contiguous injury level. In these cases, delay in diagnosis of the occult injury was from 3 to 22 days. Development of secondary neurological deficits occurred in three patients. CONCLUSIONS: A high index of suspicion and an appreciation of the extreme instability of a fracture in ankylosing spondylitis must be present.

Accidental Falls↗

The scope of unmet maternal health needs in pediatric settings.

OBJECTIVE: Previous work has focused attention on the prevalence of specific maternal health problems known to affect children, such as smoking or depression. However, the cumulative health burden experienced by mothers and the potential for a practical pediatric health services response have not been examined. The aims of this study were to characterize: 1) the prevalence and cumulative burden of maternal health behaviors and conditions, 2) maternal access to a source of comprehensive adult primary care, and 3) maternal perceptions of a pediatric role in screening and referral. METHODS: We surveyed 559 consecutive women bringing a child 18 months of age or less to one of four pediatric primary care sites between July 1996 and May 1997. The pediatric sites included one outpatient program in an academic hospital, one in a community health center, and two in-staff model practices of a managed care organization (these last two were combined for analysis). The self-administered questionnaire contained previously validated questions to assess health behaviors and conditions (smoking, alcohol abuse, depression, violence, risk for unintended pregnancy, serious illness, self-reported health) and access to care (regular source, regular provider, health insurance, care delayed or not received). Maternal attitudes toward a pediatric role in screening and referral were also elicited. RESULTS: In the three settings, response rates ranged from 75% to 84%. The average age of the women ranged from 25.1 to 32. 1 years and the average age of the children ranged from 6.5 to 8.0 months. Across the settings, the percentage of women reporting at least one health condition (66%-74%) was similarly high, despite significant demographic differences among sites. Many women reported more than one condition (31%-37%); among all women who smoked, 33% also screened positive for alcohol abuse, 31% for emotional or physical abuse, and 48% for depression. Access to comprehensive adult primary care was variable with 23% to 58% of women reporting one or more barriers depending on the site. Across all sites, >85% of mothers reported they would "not mind" or "would welcome" a pediatric role in screening and referral. CONCLUSIONS: Two-thirds of women bringing their children for pediatric care had health problems regardless of the site of care. Many women also reported substantial barriers to comprehensive health care. Most women reported acceptance of a pediatric role in screening and referral. Given the range and depth of maternal health needs, strategies to connect or reconnect mothers to comprehensive adult primary care from a variety of pediatric settings should be explored.

Adult↗

Anterior cortical allograft in thoracolumbar fractures.

A prospective cohort study of consecutive patients with thoracolumbar fractures from two centers was conducted to evaluate the use of cortical allograft for anterior spine reconstruction. The purpose was to determine whether allograft bone had deleterious effects on fusion rates and maintenance of correction. Thirty-six patients were followed for a minimum of 2 years. A radiologic fusion rate of 81% was found, and there was a loss of postoperative correction in eight patients. The addition of posterior instrumentation was not significantly different from anterior surgery alone with respect to union rates but did provide a more reliable maintenance of correction of deformity. There were no cases of disease transmission. The authors conclude that cortical allograft for anterior spine reconstruction in trauma is safe and despite having a fusion rate lower than autogenous iliac crest, little clinical significance is attributable to the radiologic appearance of nonunion at the host-allograft junctions.

Adult↗

Pediatric residency training in an era of managed care: an introduction to proceedings of a national conference.

On May 4, 1996, a conference sponsored jointly by the Division of Medicine of the Health Resources and Services Administration and the Ambulatory Pediatric Association brought together pediatric educators from academic medical centers and managed care organizations to address the challenges and opportunities for pediatric residency training, given current trends toward increasing managed care for children. This supplement is designed to bring the issues discussed there to a broader audience of pediatricians and educators. The contributions are written by the participants of that conference, with invited commentaries to add additional perspectives on each topic. The papers were reviewed by an editorial board of leaders in pediatric education with experience in relevant areas. This introduction describes the impetus for the conference and highlights a number of critical issues facing pediatric postgraduate training that are presented in greater depth in the contributions that follow. Finally, this paper summarizes the recommendations of the conference for meeting the challenges of training pediatricians in these areas.

Internship and Residency↗

Pediatric education and managed care: a literature review.

Managed care is becoming the dominant form of health care delivery and financing in the United States, necessitating changes in pediatric education. This transition is redefining the questions of what needs to be taught, who should be teaching it, where it should be taught, and how to pay for this education. We performed a literature review and examined reports from policy and professional groups to seek answers to these questions. We have identified curricular, administrative, and financial challenges to pediatric education in managed care. Although road maps for innovation have been described, there is a deficiency of research and information in key areas of pediatric education in the managed care environment.

Academic Medical Centers↗

Insertional torque and pull-out strengths of conical and cylindrical pedicle screws in cadaveric bone.

STUDY DESIGN: Insertion torque and pull-out strengths of conical and cylindrical pedicle screws were compared in human cadaveric vertebral bodies. OBJECTIVES: To compare the performance of the conical design with the cylindrical design, and to determine whether insertional torque correlates with pull-out strength. SUMMARY OF BACKGROUND DATA: A tapered pedicle screw design may lessen the likelihood of implant failure. Its effect on thread purchase is not known. Previous studies of cylindrical designs on the relation between insertion torque and pull-out strength have been conducted in bovine and synthetic bone. METHODS: Seventy-eight pedicles were assigned randomly to one of the following pedicle screw: Texas Scottish Rite Hospital (Sofamor-Danek, Memphis, TN), Steffee VSP (Acromed, Cleveland, OH), Diapason (Dimso, Paris, France), AO Schanz (Synthes, Paoli, PA), or Synthes USS (Synthes, Paoli, PA). Pedicle screws were inserted with a torque screwdriver. Each screw was extracted axially from the pedicle at a rate of 1.0 mm/sec until failure using an MTS machine (Bionix 858, Minneapolis, MN). Force data were recorded. RESULTS: The conical design had the highest insertion torque. There were no significant differences in pull-out between any of the screw types. Correlation between insertional torque and pull-out strength was statistically significant only with the Texas Scottish Rite Hospital and Steffee VSP in L4 and AO Schanz in L5. CONCLUSIONS: A conical screw profile increases insertion torque, although insertional torque is not a reliable predictor of pull-out strength in cadaveric bone. Screw profile (with similar dimensions) has little effect on straight axial pull-out strengths in cadaveric bone.

Aged↗

Open posterior dislocation of the lumbosacral junction. A case report.

STUDY DESIGN: A patient with open posterior dislocation of the lumbosacral junction is reported. OBJECTIVES: Treatment with primary anterior open reduction with internal fixation followed by delayed posterior stabilization and fusion. SUMMARY OF BACKGROUND DATA: This injury has been reported previously on two occasions; however, anterior stabilization was not used. In this case, anterior fixation was necessary because of the posterior soft tissue contamination. METHODS: After an anterior open reduction of L5-S1, stabilization was performed using instrumentation. Posterior wound care was then performed, with delayed posterior fusion and instrumentation of L5-S1 at 2 weeks. RESULTS: At 18 months there was solid fusion of the lumbosacral junction with no evidence of infection. CONCLUSIONS: Satisfactory results were obtained when principles of open fracture management were followed. Primary anterior stabilization allowed appropriate wound care. Definitive posterior stabilization and fusion can be done when soft tissue stability is obtained.

Adult↗

Oral Ambu-bag insufflation to remove unilateral nasal foreign bodies.

The nose is perhaps the most common site for the insertion of foreign bodies by children. Removal is essential. We report the successful use of the oral Ambu-bag insufflation technique to remove unilateral nasal foreign bodies in three children. Conscious sedation was not required. There were no complications.

Child, Preschool↗

Lower limb compartment syndrome: course after delayed fasciotomy.

OBJECTIVE: To determine the end result of patients who underwent delayed fasciotomy, i.e., more than 35 hours for an established lower limb compartment syndrome. DESIGN: A retrospective review of patients undergoing delayed treatment for a closed injury of the lower extremity, where fasciotomy should ideally have been performed earlier. MATERIALS AND METHODS: Nine fasciotomies in five patients were identified where there was a delay of more than 35 hours after the injury. The average ischemic time was 56 hours (range 35-96 hours). RESULTS: One patient died of multiorgan failure and septicemia. The remaining four patients required lower limb amputation, because of local infection and septicemia. The one late amputation was performed 6 months after the injury, because the patient was left with a functionless insensate foot. Where recognition of an established compartment syndrome is delayed for more than 8 to 10 hours, we propose that the traditional inevitable fasciotomy be reassessed.

Amputation, Surgical↗

Sensitivity of new-generation computed tomography in subarachnoid hemorrhage.

OBJECTIVE: To determine the sensitivity of the initial new-generation CT (NGCT) scan interpretation for detection of acute nontraumatic subarachnoid hemorrhage (SAH) and to decide whether lumbar puncture (LP) should follow a "normal" NGCT scan. METHODS: A retrospective chart review was performed of patients admitted between March 1988 and July 1994 with proven SAH. Exclusion criteria were age < 2 years, diagnosis other than acute SAH, history of head trauma within 24 hours before symptom onset, NGCT scan not done before diagnosis, and records not available. Patients were placed into two groups: symptom duration < 24 hours (group 1) and > 24 hours (group 2) prior to CT scan. The resolution of each NGCT scanner was recorded. An NGCT scanner was defined as a third-generation scanner or more recent. RESULTS: Of 349 SAH patients, 181 met inclusion criteria. The sensitivity of NGCT scans for SAH was 93.1% for the group 1 patients (n = 144) and 83.8% for the group 2 patients (n = 37). The overall sensitivity was 91.2%. All the patients who had SAH not detected by NGCT scans were diagnosed by LP. There was no significant relationship between NGCT scanner resolution and sensitivity for SAH. CONCLUSION: Initial interpretation of NGCT scans to detect SAH does not approach 100% sensitivity. A "normal" NGCT scan does not reliably exclude the need for LP in patients who have symptoms suggestive of SAH.

Adolescent↗

Varus osteotomy of the distal part of the femur. A survivorship analysis.

Varus osteotomy of the distal part of the femur is often the procedure of choice for the treatment of osteoarthrosis of the lateral compartment associated with genu valgum. We followed twenty-one knees (twenty patients) long term or until failure. At the most recent evaluation (average, 133 months; range, ninety-seven to 240 months), thirteen osteotomies were still successful, seven had failed, and one patient (in whom the knee had remained functional) had died. Of the seven failures, three occurred early (at twelve or twenty-four months) and four occurred late (between seventy-two and ninety-eight months). The probability of survival at ten years was 64 per cent (95 per cent confidence interval, 48 to 80 per cent), as determined with use of the Kaplan-Meier method. We concluded that, with proper selection of patients, this procedure is effective for the treatment of gonarthrosis of the lateral compartment associated with valgus deformity.

Adult↗

Urine Trinder spot test: a rapid salicylate screen for the emergency department.

STUDY OBJECTIVE: To determine whether the urine Trinder spot test, performed by emergency physicians, is a sensitive bedside screen for salicylates. DESIGN: Prospective, blinded human protocol with subjects serving as their own controls. SETTING: Urban Level I medical center. PARTICIPANTS: Ten male and two female volunteers with negative urine toxicologic screen results before the start of the study. INTERVENTIONS: Each participant ingested 975 mg of nonenteric coated aspirin. Serum and urine samples were collected before ingestion and 2 and 4 hours after ingestion. Three emergency physicians and a toxicology technician independently performed Trinder spot tests. Results were recorded as positive or negative for salicylate on the basis of color change (a purple reading was considered positive). RESULTS: All postingestion urine specimens were detected by all testers with 100% sensitivity. Two false positives occurred in the preingestion samples. Serum quantitative assays confirmed the presence of salicylates in all postingestion specimens. CONCLUSION: This pilot study suggests that emergency physicians can use the Trinder spot test as a sensitive bedside salicylate screen, potentially saving time and quantitative assay expense.

Adult↗

A Madreporic-surfaced femoral component in a canine total hip arthroplasty model: bone remodelling response at 6 and 24 months.

OBJECTIVE: To evaluate the bone-remodelling response at 6 and 24 months after total hip arthroplasty around a two-thirds Madreporic-surfaced femoral component in a canine model. DESIGN: A research study in dogs. Statistical analysis was by multivariate analysis of variance. SETTING: A musculoskeletal research laboratory in a university teaching hospital. MATERIAL: Ten mature mixed-breed dogs. INTERVENTION: Unilateral implantation of total hip arthroplasty in the right femur with a Madreporic-surfaced prosthesis. Studies were conducted at 6 months in five dogs and at 24 months in five dogs. In each case, the nonoperated femur was the study control. MAIN OUTCOME MEASURES: Fluorescence microscopy analysis on comparable sections at four levels of the femora, percent porosity computed by image analysis, cortical atrophy. RESULTS: Cancellous hypertrophy was most prominent at the junction of the beaded and smooth portions of the femoral stem. At 6 months the cortex demonstrated atrophy predominant in the anteromedial quadrant. Active bone turnover was present within the interstices of the prosthesis at 6 and 24 months. No significant cortical bone loss occurred between 6 and 24 months. Stress transfer to the bone-prosthesis interface and endosteal cortical "cancellization" appear to be linked phenomena.

Animals↗

Acute posterior fracture dislocations of the shoulder treated with the Neer modification of the McLaughlin procedure.

Posterior dislocation of the shoulder may be associated with an anteromedial impaction fracture rendering the shoulder unstable in internal rotation. The modified McLaughlin procedure as described by Neer involves transplanting the lesser tuberosity with the attached subscapularis tendon into the anteromedial defect. We have used this procedure acutely (from the day of injury to 10 days postinjury) in seven shoulders. All patients were unstable in internal rotation and had an anteromedial impaction fracture occupying 25-40% of the articular surface. This technique provides good stability, enables immediate active range of motion, and allows the patient to rapidly return to activities of daily living.

Aged↗