Search PubMed⌕ Search

Biomedical subjects

J A Dalziel

Publications and source records attributed to J A Dalziel.

5 recordsLinked to original sources

Tremor and senile parkinsonism.

A study of 100 Day Hospital patients showed that 26 elderly patients with mild Senile Parkinsonism and varying degrees of dementia had subclinical tremor with the same frequency as Parkinson's Disease and distinguishable by amplified recordings from those of Parkinson's Disease and Senile Tremor. A significant history of cerebro-vascular disease was obtained in one-half of these patients. The recording of tremor is shown to be of value in diagnosing Parkinsonism and in assessing response to treatment.

Dementia↗

Progressive systemic sclerosis in the elderly.

There is evidence to suggest that the incidence of progressive systemic sclerosis in the elderly is more common than in younger age groups. As in younger patients, late onset cases may have minimal skin changes and this can cause difficulty in diagnosis. The case histories of 2 patients are presented to illustrate these points.

Aged↗

Progressive supranuclear palsy.

In the past four years, four patients with progressive supranuclear palsy have presented to the Department of Geriatric Medicine, Oxford, under the care of one of us (RAG). They were all females whose symptoms began in the sixth or seventh decade. They died from three to six years after the onset of symptoms. All had neuropathological studies which are described. The presenting characteristics included frequent falls, difficulty in walking, nuchal rigidity, abnormalities of gaze, pseudobulbar features and mild dementia. These are features particularly common in the elderly and it is suggested that the condition may be under-diagnosed.

Aged↗

Cathodic stripping voltammetry of nanogram amounts of selenium in biological material.

A method is described to determine selenium in biological material, based on cathodic stripping voltammetry. Following wet ashing, the selenium was extracted into benzene as the 3',4'-diaminophenylpiazselenol. The selenium was subsequently back-extracted into dilute acid for analysis. Analyses of NBS Bovine Liver demonstrated that the method was capable of recovering 96+/-9% of the selenium present. The detection limit and working range were 3 ng/g and 0-10,000 ng/g, respectively. The method was also applied to the determination of selenium in rapeseed oils and seed.

Animals↗