Search PubMed⌕ Search

Biomedical subjects

J A Collins

Publications and source records attributed to J A Collins.

At least 127 records · Page 7Linked to original sources
PubMed1977

Induction of midtrimester abortion with intra-amniotic urea and intravenous oxytocin.

Midtrimester abortions were induced in 295 patients with a combination of intra-amniotic urea and intravenous oxytocin. The mean injection-abortion interval was 26.4 hours. Abortion occurred spontaneously within 50 hours of amnioinfusion in 257 patients. The macerating effect of the hypertonic urea on fetal tissues allowed easy termination of the remaining 38 pregnancies by suction curettage at 50 hours after injection. Decreased urinary output occurred during the oxytocin infusions, but water intoxication was prevented by close monitoring of urinary output and serum electrolytes, and by the use of a concentrated solution of oxytocin in normal saline, allowing the administration of small volumes.

Abortion, Induced↗
PubMed1976

Verrucous carcinoma of the vagina.

Verrucous carcinoma of the vagina is a highly differentiated and rare variety of squamous-cell carcinoma. Two new cases are presented; a search for the literature revealed three other cases. This neoplasm is characterized by a warty verrucous pattern of growth of squamous epithelium. Histologically, this type of squamous-cell carcinoma is extremely well-differentiated, with minimal evidence of anaplasia of the cells. The neoplasm tends to grow slowly and to infiltrate, sometimes extensively, by pushing rather than by permeating the surrounding tissues. Surgical excision seems to provide the best cure at the present time as the tumor does not respond to irradiation or to podophyllin treatment. Lymph-node dissection is not usually necessary in view of the tendency of the tumor to spread locally rather than to metastasize. However, the value of resection of lymph nodes should be reassessed after enough cases have accumulated.

Carcinoma, Verrucous↗
PubMed1976

Observations on the biochemical effects of transfusion of citrate-phosphate-dextrose stored blood in man.

Preliminary data on the biochemical effects of the transfusion of three units of CPD blood in man is presented. Free (ionized) calcium was found to decrease approximately two minutes following initiation of the transfusion of CPD stored blood at a rate of 50 ml/min. Due to mixing problems, arterial and not venous specimens were found necessary to monitor accurately the severity of these decreases. Parathyroid hormone in the peripheral blood was found to increase two to four minutes after the initiation of transfusion. Decreases in blood pressure were observed during transfusion. The blood pressure recovered when the transfusion was stopped and did not decrease any further after restarting the transfusion, were found out not to increase or decrease consistently, and only modest changes in plasma potassium were observed.

Aged↗