Search PubMed⌕ Search

Biomedical subjects

J A Coller

Publications and source records attributed to J A Coller.

At least 109 records · Page 6Linked to original sources

Colostomies--indications and contraindications: Lahey Clinic experience, 1963--1974.

Over a 12-year period, 276 temporary colostomies were performed on 271 patients. During this interval 118 colostomies were closed. The morbidity rate of colostomy construction was 21 per cent, and for closure it was 49.1 per cent. No definite factor could be indentified as contributing to this high rate of complications for colostomy construction. With respect to colostomy closure, predisposing factors that seemed to increase morbidity were shorter interval between creation and closure of the stoma and resection of colostomy (as opposed to closure without resection). Intra-abdominal drains were associated with a prohibitively high rate of wound infection, although subcutaneous drainage was not successful in reducing the incidence of infection significantly.

Adolescent↗

Colonic hemorrhage.

We have briefly presented our concepts of the investigation and management of lower intestinal bleeding. Such bleeding was divided into massive and nonmassive colonic hemorrhage, and the differences in the investigative techniques were discussed for each of these circumstances. An algorithm of our diagnostic and management protocol for massive large bowel hemorrhage may be followed in a somewhat varied fashion in the investigation of those patients having nonmassive large bowel bleeding.

Barium Sulfate↗

Ileostomy complications requiring revision: Lahey clinic experience, 1964-1973.

From 1964 to 1973, 50 patients who initially underwent ileostomy for inflammatory bowel disease at the Lahey Clinic required 84 revisions. The commonest reason for revision was stenosis. Fistula, prolapse, and retraction followed in order of frequency. Patients with Crohn's disease seemed to have a higher incidence of revision, but this was not statistically significant. Other reasons for revision were analyzed, and recommendations for treatment were discussed. Retrospective study revealed that 50% of ileostomy revisions were performed for probably preventable complications.

Adolescent↗

Anastomotic recurrence after anterior resection for carcinoma: Lahey Clinic experience.

A retrospective study of 152 patients who underwent anterior resection for carcinoma of the rectum and rectosigmoid from 1963 to 1969 is presented. Eighteen anastomotic recurrences (two benign) were observed. Factors associated with high recurrence rates are discussed, and a scheme for identification of those patients in high-risk groups is presented. The value of this study lies in facilitating decisions involving operative and postoperative management of distal colonic lesions.

Adult↗

Anterior resection for adenocarcinoma. Lahey Clinic experience from 1963 through 1969.

The results of anterior resection for adenocarcinoma of the rectum and rectosigmoid are reported with respect to survival rates and complications. Anastomotic recurrence is related to low lying, ulcerated, and less well differentiated tumors that have penetrated the bowel wall. The incidence of recurrent disease at the anastomosis increases with decreases in the margin of resection. Distal margins of at least 6 cm offer significant protection from recurrence. This study shows that anastomotic septic and fistulous complications are related to advanced age, diabetes, anemia, atherosclerotic disease, construction of the anastomosis below the peritoneal reflection, perforated bowel, obstructed bowel, and the use of drains. The determination of those factors that correlate with the development of anastomotic complications can be accomplished with pre- and intraoperative examinations. The role of these factors in operative decision-making and patient management is emphasized.

Adenocarcinoma↗

Colonic polypoid disease: need for total colonoscopy.

Colonoscopic examination of the entire colon was performed on 146 patients for radiographically suspected benign polypoid disease. Of thirty-six patients who did not have a neoplastic lesion at the suspected site, seven (19 per cent) had unsuspected small benign polypoid adenomas elsewhere in the colon. Of the remaining 110 patients who had a neoplastic lesion at the radiographically suspected site, 17 lesions (15 per cent) were either adenocarcinomas or neoplastic polyps with invasive carcinoma. One hundred twenty-eight additional unsuspected neoplastic polyps were found in 62 of the 110 patients (56 per cent). Six of the additional neoplastic lesions were either adenocarcinomas or polyps with invasive carcinoma. Four of these malignant lesions were in patients who had a benign polyp at the radiographically suspected site. Suspected colonic polypoid disease should be evaluated colonoscopically despite radiographic evidence of benignity. Colonoscopic evaluation in colonic polypoid disease should include examination of the entire colon with pathologic documentation of all polypoid lesions encountered.

Colonic Neoplasms↗

Symposium: Procidentia of the rectum: teflon sling repair of rectal prolapse, Lahey Clinic experience.

The Teflon-sling method of repair of rectal prolapse in the Lahey Clinic experience has proved to be one of no mortality and low morbidity, with a recurrence rate of 7.3 per cent over an average follow-up period of nearly four years. Bowel management and incontinence are problems inherent in the pathogenesis of the problem and, though improved, necessitate long-term patient re-education and physiotherapy. More than 85 per cent of the patients were satisfied with the results of the procedure.

Adult↗

Recent thoughts on the development of colorectal cancer.

Considerable evidence demonstrates that a relationship may exist between adenomatous polyps and carcinoma. While the evidence may be circumstantial, it is not unimpressive. A recently completed 18 year follow-up of patients with benign polyps initially fulgurated demonstrates a statistically significant higher incidence of the development in colorectal carcinoma in these patients than in the unaffected population.

Blood Vessels↗

Cathartics.

Explore the source record for details and available documents.

Cathartics↗