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Biomedical subjects

J A Callahan

Publications and source records attributed to J A Callahan.

32 records · Page 2Linked to original sources

Echophonocardiographic findings in patients with prosthetic heart valve malfunction.

This report represents a retrospective analysis of preoperative echophonocardiographic studies in 118 patients who had surgery for the repair or replacement of malfunctioning prosthetic valves. A variety of prostheses implanted in the mitral, aortic, and tricuspid positions were assessed. The most frequent prosthetic malfunctions were regurgitation, thrombosis, ball variance, and infective endocarditis. There were echophonocardiographic abnormalities in 71% of the cases. The retrospective diagnosis of prosthetic dysfunction varied according to the type of prosthesis, type of malfunction, and site of implantation of the valve. A high percentage of the prostheses did have echophonocardiographic abnormalities, and consideration of these, in conjunction with clinical data, may help the clinician in the evaluation of prosthetic heart valves.

Adult↗

Prinzmetal's variant angina--response to verapamil.

A patient with frequent attacks of Prinzmetal's variant angina complicated by ventricular tachycardia and ventricular fibrillation is described in whom these episodes persisted daily during 4 weeks of hospital observation in spite of treatment with nitrates, alpha-adrenergic-blocking drugs, and anticholinergic agents. The oral administration of verapamil, an investigational vasodilator drug, led to prompt and complete resolution of the attacks.

Adult↗