Cryptococcosis.
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AIDS-Related Opportunistic Infections↗
Biomedical subjects
J A Aberg
Publications and source records attributed to J A Aberg.
Immunoglobulin G immunosuppression of multiple sclerosis. Suppression of all three major lymphocyte subsets.
Six patients with relapsing chronic progressive multiple sclerosis were treated on 2 consecutive days with large amounts of IgG to induce immunosuppression. Peripheral blood lymphocyte subsets were monitored for 5 weeks after IgG treatment to determine immunosuppression. Decreased numbers of B, T, and natural killer lymphocytes were detected after treatment. Lymphocyte numbers were at a nadir 1 week after treatment, but an immunosuppressive effect continued to be present after 5 weeks. Although clinical efficacy was not evident in this brief open trial, the decrease of peripheral lymphocyte numbers and the apparent safety of the procedure warrant further study.
Adult↗
Prostaglandin production in chronic progressive multiple sclerosis.
Peripheral blood monocytes have been implicated in the immune reactions that accompany demyelination in patients with multiple sclerosis (MS). We measured prostaglandin E2 (PGE2) and thromboxane B2 (TxB2) release from peripheral monocytes exposed in vitro to complement. Our studies suggest that there is a significantly higher production of PGE2 in monocytes from patients with chronic progressive MS than in those with exacerbation or remitting MS and healthy controls. No significant differences in TxB2 release were noted between the three groups.
Chromatography, High Pressure Liquid↗
Idiopathic hypoparathyroidism in a blind, deaf, elderly woman with dementia.
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Aged↗