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Biomedical subjects

Iu V Linevskiĭ

Publications and source records attributed to Iu V Linevskiĭ.

At least 19 recordsLinked to original sources

[Evaluation of diagnostic indices of reactivity during treatment of patients with chronic bronchitis and bronchiectatic disease].

Evaluation of neutrophils conditions by glycogen, enzymatic activity (acid and alkaline phosphatases, peroxidase), lymphocyte blast-transformation reaction stimulated by staphylococcal antigen in 113 patients with bronchial pathology on treatment suggested the conclusion of their value in verification of the disease course correction of on-going treatment and definition of its effect. The methods acquire additional significance in objective assessment of the process activity in obscure clinical manifestations and lack of laboratory evidence for aggravation.

Bronchiectasis

[The prognostic value of immunologic indices in chronic pancreatitis].

Analysis of clinical and immunologic parallels in 200 patients with chronic pancreatitis has revealed that lymphocyte autosensitization to pancreatic tissue in the lymphocyte blastogenesis test (LBGT) is in high correlation with the frequency of the disease recurrences, and the severity of pancreatic exocrine insufficiency with the immune complex level. This permits recommending LBGT with pancreatic tissue antigen for the prediction of the condition recurrences, and measurements of the immune complexes level for the prediction of the developing exocrine pancreatic insufficiency.

Antigen-Antibody Complex

[The dynamics of the indices of reactivity of the body in patients with chronic bronchitis and bronchiectasis in the course of treatment].

Complex determination of lymphocyte functional activity and the condition of the organism's immunological values in patients with chronic bronchitis and bronchiectasis helps in obtaining additional objective information which makes it possible to appraise the severity of the course of the disease, correct the treatment and determine its efficacy in different stages of the disease, come to a decision in regard to operative intervention, and form a judgement on the fullness of recovery. These tests acquire additional diagnostic value in patients with mild clinical manifestations of the disease as well as in the absence of its laboratory signs. A direct dependence between the severity of the disease and the above named values was revealed.

Bronchiectasis

[The immunological reactivity indices of patients with chronic nonspecific lung diseases].

At height of the disease patients with chronic bronchitis showed a reduction of immunological indices of reactivity of the body. A direct dependence was established between the severity of the course of the disease and degree of reactivity reduction. Absence of complete normalization of indices of immunological reactivity at discharge from the clinic indicates incomplete control of the inflammatory process and short-term character of the remission. The reaction of lymphocyte blast transformation may be used for detection of both latent and clinically manifest staphylococcal infection. Increased sensitivity to staphylococcal allergen results in a reduction of the phagocytic activity of neutrophils in patients with chronic bronchitis.

Antigen-Antibody Reactions