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Biomedical subjects

Iu V Isakov

Publications and source records attributed to Iu V Isakov.

At least 19 recordsLinked to original sources
PubMed1990

[Hyperbaric oxygenation in acute compression-dislocation syndrome (experimental-morphological study)].

Acute compression dislocation syndrome was reproduced in rabbits by means of epidural brain compression with a balloon. After elimination of brain compression the main group were treated by HBO whereas the control group did not receive HBO. The use of HBO resulted in a decrease of the lethality in hyperextension manifestations. Using the total water measurement in the brain the main group was discovered to have a decrease of brain edema at different times, associated with compression and eliminated compression thereof. Microscopy revealed a reduction of pericellular, perivascular and subependymal edema as well as of edema of vascular plexus and venous brain plethora under the influence of HBO.

Acute Disease↗
PubMed1989

[Effects of hyperbaric oxygenation in acute compression-dislocation syndrome in experimental animals].

A model of the acute compression dislocation syndrome of grave degree was designed by means of local compression of the parietotemporal area of rabbit brain. A study was made of the effect produced by hyperbaric oxygenation (HBO) on the syndrome after compression elimination. HBO has been noted to decrease the lethality, primarily among animals with the gravest manifestations of the syndrome, to bring about frequent and more full-value recovery of the survived animals, and an insignificant lowering of brain edema.

Acute Disease↗
PubMed1988

[Effect of hyperbaric oxygenation on the dynamics of the alcohol abstinence syndrome].

Hyperbaric oxygenation (HBO) was used in 40 patients with the alcoholic abstinence syndrome (AAS), Stages I and II severity, either as a component of multiple modality (in combination with drugs) or the only treatment. The results of clinico-psychoneurological examination have demonstrated that the use of HBO in the treatment of patients with the AAS significantly accelerates the time of AAS elimination as compared with the control group receiving drug therapy alone. An HBO session markedly reduces psychoneurological and somatovegetative symptomatology which is attended by a reduction in systolic blood pressure and in the heart rate. Analysis of the electrocardiographic findings obtained in patients with alcoholic involvement of the heart at the height of the AAS has shown that HBO helps improve the myocardial status. The best results are achieved in patients with Stage II AAS when HBO therapy (two sessions daily) is started at early stages of the syndrome.

Adult↗
PubMed1987

[Clinical effectiveness of hyperbaric oxygenation in the combined treatment of patients with schizophrenia].

Hyperbaric oxygenation (HBO) was employed in 50 schizophrenic patients showing resistance to the conducted drug therapy. Thirty-two patients had shift-like and 18, sluggish, moderately and slowly progressive forms of schizophrenia. HBO treatment was always combined with psychopharmacotherapy. The results of the study have shown the advisability of inclusion of HBO into the multiple-modality treatment of patients with asthenic and apathetic depressions encountered during a shift-like or sluggish, schizophrenia with hysteric-hypochondriac disturbances and obsessions. The maximum therapeutic effect was observed after 10-12 sessions of HBO.

Combined Modality Therapy↗
PubMed1985

[Effect of hyperbaric oxygenation on the course of experimental brain edema].

The authors studied experimental brain edema and morphological changes in the cerebral tissue in 2 groups of animals: the test group receiving hyperbaric oxygenation (HBO) and the control group. The test animals showed a more favourable course of brain injury. Microscopic examination revealed a lesser degree of brain edema and intensification of reparative processes in the cerebral tissues of animals receiving HBO.

Animals↗
PubMed1984

[Hyperbaric oxygenation in the prevention of mental disorders in patients during the acute period of severe craniocerebral injuries].

On the basis of a comparative analysis of the incidence of psychic disturbances seen in two groups of patients with craniocerebral trauma (subjects receiving HBO treatment and those without it), it is concluded that HBO is effective in preventing trauma-associated psychoses. The effect of HBO on the external respiration and central hemodynamics was also examined. The obtained results formed the basis for discussing possible pathogenetic mechanisms of hyperbaric oxygen action in this pathology.

Affective Symptoms↗
PubMed1983

[Hyperbaric oxygenation in paroxysmal and extrasystolic disorders of cardiac rhythm].

Hyperbaric oxygenation (HBO) was used as part of combined treatment in 102 patients with frequent paroxysms of atrial fibrillation and supraventricular tachycardia, and extrasystoles associated with coronary disease in 74 and neurogenic disturbances in 28 patients. HBO was indicated where anti-arrhythmic drugs had proved inefficient. Electrocardiographic, hemodynamic (rheographic), spirographic parameters and blood catecholamines were examined. Extrasystoles became less frequent or disappeared altogether for varying intervals in 75% of coronary patients, the duration of disappearance depending on the duration of their former presence. Stable disappearance of extrasystoles for 6-12 months was noted in 50% of coronary patients with less than two years' existence of extrasystole. In atrial fibrillation paroxysms due to coronary disease, HBO-incorporating combined treatment eliminated paroxysms for 4 to 10 months. In addition to normalizing cardiac rhythm, HBO increased formerly low cardiac output, reduced hyperventilation, eliminated respiratory arrhythmias and brought down blood catecholamine levels.

Arrhythmias, Cardiac↗
PubMed1982

[Hyperbaric oxygenation in the acute period of craniocerebral injuries].

A study was made of the effect of hyperbaric oxygenation (HBO) on the clinical progress of craniocerebral trauma by means of a comparative analysis of the time course of the clinical symptoms and the occurrence of complications seen in the main group of patients given HBO (103 subjects) and the control group not given HBO (also 103 subjects). Some of the parameters of external respiration and central hemodynamics were examined in these patients during HBO. It was disclosed that HBO exerts a prophylactic action as regards the development of mental disorders in the acute period of brain trauma and some complications (meningitis, suppuration of operative wound, bedsores, pneumonias). HBO had no noticeable effect on the rate and degree of the recovery of motor and speech functions. In part of cases, HBO eliminated the hyperventilation syndrome and the pathological rhythm of respiration and myocardial hypodynamia.

Acute Disease↗
PubMed1981

[Hyperbaric oxygenation in the combined treatment of paroxysmal tachyarrhythmias in ischemic heart disease].

From experience in the use of the hyperbaric oxygenation (HBO) in 31 patients and study of the ECG and central hemodynamic parameters by integral rheography the authors came to the conclusion that HBO reduces the number and duration of the paroxysms and that long-term remissions occur. HBO also reduces the number of extrasystoles, but the effect is of a short duration. During the paroxysms the HBO session promotes the change from the tachysystolic form of atrial fibrillation to the normosystolic form. A course of HBO therapy exerts a long-term normalizing effect on hemodynamics in myocardial hypodynamia.

Adult↗
PubMed1981

[Effect of hyperbaric oxygenation on patient hemodynamics and respiration in blood loss as a consequence of gastroduodenal hemorrhages].

Hyperbaric oxygenation (HBO) was used in the complex of treatment of 52 patients who had blood loss due to gastroduodenal hemorrhage. Barocameras were used with the maximum pressure of 1.6--2.0 atm for 40 min. 6--10 sessions for a course. The sessions of HBO while reducing hypoxia could eliminate the compensatory hyperfunction of the myocardium and decrease the extra-load on the heart. The external ventilation function was not substantially influenced by the sessions of HBO.

Adolescent↗