[Surgical treatment of leiomyosarcoma of the pulmonary artery under artificial circulation].
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Biomedical subjects
Publications and source records attributed to Iu V Biriukov.
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Importance of laparoscopy (LS) in diagnosis of intraabdominal catastrophe in patients with combined trauma (CT) is determined. Based on analysis of treatment results in 1,118 patients with CT it was revealed that real LS requirement does not exceed 10%, and it may influence negatively trauma outcome. Low diagnostic value of this method was revealed: sensitivity 98.4%, specificity 51%, accuracy 69.2%. It is concluded that LS is not a method of choice in diagnosis of intraabdominal injuries in patients with CT.
Experience in treatment of 164 patients with combined trauma of abdomen and pelvis is analyzed. Mean age of the patients was 40.1+/-17 years, 94 patients were male, 70 -- female. ISS was 28.6+/-11 points. Lethality was 44.5%, during first day -- 61.6%. High lethality may be associated with mistakes in surgical and traumatological policy. Abdominal surgery was performed in 64 (39%) patients, only in 24 (14.6%) of them laparotomy was curative, the rest 40 (85.4%) patients underwent diagnostic laparotomy. It is demonstrated that diagnostic laparotomy has negative influence on prognosis of combined trauma of the abdomen and pelvis. Adequate traumatological policy has also great influence on lethality, particularly during the first day. Overall lethality of patients with rotary-vertical instability of the pelvis was lower in the group with fixation of the pelvis than in conservatively treated patients (41.7 and 56.6%). Lethality during day 1 in patients with fixed pelvis was 0, without fixation of the pelvis -- 82%. It is concluded that verified indications for laparotomy and active traumatological policy improve treatment results in patients with combined trauma of abdomen and pelvis.
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Among 29,875 autopsies 59 cases of mediastinal echinococcosis were revealed. Among 4178 patients with thoracic echinococcosis 55 patients had mediastinal echinococcosis. All the patients were operated, most of them underwent ideal ecinococcectomy. Intraoperative prophylaxis of echinococcosis was performed: plearal cavity was treated by low-frequency ultrasound and glycerin. 7 examined patients demonstrated reduction of immune and phagocytosis indices in blood (DC3+, CD4+, CD8+, CD16+, CD21+). Increase of immunoglobulines A, M, G and circulating immune complexes was revealed. Reactions of scolexprecipitation and lymphocytes antigen-fixing were positive.
Diagnostic value of verification methods for abdominal injuries in patients with combined trauma (CT) was analyzed, severity of injuries by Injuries Severity Scale (ISS) was specified. From 503 patients with CT (ISS = 17.6 +/- 9) diagnostic laparocentesis (DLC) was used in 224 (44.6%), USI--in 204 (40.4%), diagnostic laparoscopy (DLS)--in 49 (9.8%). Diagnostic value of each method is not optimal as they do not confirm or exclude injuries of abdominal organs requiring emergency surgery. Absence of clear criteria of diagnosis of intraabdominal catastrophe leads to significant number of unnecessary laparotomies (DLC--39%, USI--43%, DLS--48.6%) that makes graver state of patients with CT and prognosis.
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Experimental series of 60 cotton rats and 150 white mice infected with echinococcus showed that 80-100% glycerin and 3% peroxide solution were effective scolicidal solutions for inactivation of the parasite. 344 patients have been operated on for hydatid disease with inactivation of the parasite by means of these scolicidal solutions. Glycerin during the surgical management of the hydatid cysts is effective and harmless in uncomplicated hydatid liver disease and any hydatid pulmonary cysts. Glycerin is contraindicated in complicated hydatid liver disease because of immunity disturbance. In complicated hydatid liver disease management of the hydatid cysts by 3% peroxide is effective and harmless. It is necessary to correct the hydatid liver disease patients' immunity in the preoperative and postoperative periods. Tactivin and antiechinococcus drug SK-1 are effective immunomodulators in hydatid liver disease.
The aim of this study was to analyse the results of the treatment of extraperitoneal rectal and perineal injuries for 153 patients. All the patients were examined according to the scheme. Therapeutic-diagnostic algorithm was developed for perineal, anal, rectal injuries. Wide opening and drainage of the wound was used. The method allows to avoid colostomy and its subsequent operative closing in extraperitoneal injury of the rectum. The method of surgical treatment is recommended in extraperitoneal rectal and perineal injuries.
The analysis of treatment results in 112 patients with foreign bodies in the rectum, aged from 16 to 80 years, was carried out. 99.1% of the patients were men. All the patients were examined and treated in proctology department of the Moscow municipal clinical hospital N 67 from 1969 to 1998. The examination was made by standard scheme, including rectal touch, rectoromanoscopy, X-ray and ultrasonic examinations. In 107 patients the foreign body was removed without surgery, 5 patients required laparotomy. When possible it was removed by fingers and also with use of forceps. When small foreign bodies could not be reached by finger, they were removed through rectoscope. Foreign bodies of big sizes, proximal end of which was in the sigmoid colon, were removed under anasthesia with the help of the assistant who fixed the foreign body through the abdominal wall in the left ileac region. In impossibility of the subject removal by these methods and presence of complications (perforation, peritonitis), laparotomy with subsequent transanal subject removal without colon section was performed, in case of perforation--with wound suturing or colostomy.
The study is based on the results of conservative and operative surgical treatment of 184 victims with open and closed, isolated and combined injuries of the liver. The patients' age was from 15 to 80 years. All patients were examined and treated in 1991 to 1996 in Moscow clinical hospital No 67. Conservative treatment for superficial injuries of the liver were carried out in 72 patients. 112 patients underwent urgent operations. Conservative treatment included: examination, control diagnostic laparoscopy and introduction of control drainage followed by dynamic laparoscopy. Operative treatment included: laparotomy, revision of the abdominal cavity, sutures or resection of the liver, surgical treatment of the other abdominal organs. Comparative analysis of two methods of treatment demonstrated possibility and necessity of the use of conservative treatment for superficial injuries of the liver, especially in combined traumas.
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The authors present the analysis of the results of examination and treatment of 156 patients (84 females and 72 males aged from 7 to 69 years) with primary tumors of the trachea. Morphological types of primary benign and malignant tumors of the trachea and peculiarities of their clinical features are described. Diagnosis was based on clinical symptoms, results of roentgenologic examination and tracheobronchoscopy with biopsy. Surgical methods of treatment were endoscopic and open operations on the trachea. Endoscopic methods are of great importance in removal of benign tumors of the trachea as well as a preliminary stage before elective operation in subcompensated and decompensated neoplastic stenosis for elimination of stridor respiratory insufficiency and for decrease of secondary inflammatory disturbances in respiratory airways. In cases of extended resections of the trachea a series of special modes was provided for elimination of tension during anastomosis formation. Follow-up results of resections of the trachea for benign tumors are quite favourable. In cases of malignancies they are significantly worse. Survival of patients depends on histological type of the tumor and on the variant of resection of the trachea.
Histologic and morphometric examination comprised surgical and autopsy material of 20 patients with bronchiectatic disease and 14 patients with chronic bronchitis, respectively. The control group consisted of 14 autopsy follow-ups of the lungs of subjects who had neither pulmonary diseases nor heart defects. Structural reorganization of the lungs in both diseases was characterized by enlargement of the middle and inner coats of arteries, hyperplasia of their inner elastic membrane and hypertrophy of the middle coat of veins. Changes mainly developed on the level of the subsegmental bronchi and bronchiectases. A direct correlation was seen between the degree of hypertrophy of the walls of bronchial vessels and those of the pulmonary artery. Participation of bronchopulmonary shunting in the development of lung hypertension is discussed.
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Experiments on 10 mongrel dogs demonstrated the efficacy and reliability of argon plasma flux in achieving hemo- and aerostasis in surgical debridement of gunshot wounds of the chest "Fakel" plasma surgical complexes were used as a source of plasma. A total of 43 operations were performed on patients whose ages ranged from 16 to 68 years: pulmonectomy 3, lobectomy 24, bilobectomy 4, atypical resection of the lung 4, pleurectomy with lung decortication 5, diagnostic thoracotomy 2, rib resection 1. Argon plasma flux was used in thoracotomy, treatment of wound surfaces of the lungs and pleura, separation of the interlobar fissures, and division of the main and lobar bronchi. The plasma flux produced an analgesic effect; as a result much less narcotics and analgesics were needed and physical activity was permitted earlier. The amount of discharge from the pleural cavity along the drain was 1.5-2 times less (200 +/- 40 ml) as compared to that in the traditional methods for conducting similar operations. No complications associated with application of plasma flux were noted. Incompetence of the bronchial stump, rethoracotomy for bleeding or suppuration were not encountered.
In the Department of Surgery of Lungs and Mediastinum, National Research Centre of Surgery, USSR AMS, 88 patients underwent operation for lung carcinoma extending into the thoracic wall (which accounted for 2.6% of all patients who were operated on for carcinoma of the lungs) from 1963 to December 1990. Surgical treatment of such patients is the method of choice. The performance of both radical and palliative operations is expedient. The survival of patients after operation is determined by the depth of invasion of the thoracic wall by lung carcinoma and the condition of intrathoracic lymph nodes.
Experimental studies on 18 mongrel dogs showed that resection of large bronchi can be accomplished effectively with a plasma scalpel even in the presence of purulent bronchitis. Reliable hemo- and aerostasis are provided, a marked bactericidal effect is produced, the zone of irreparable thermal changes is relatively small, and proliferative processes prevail in healing. The obtained information allow plasma scalpel to be recommended for resection of large bronchi in clinical practice.