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Biomedical subjects

Iu P Petrunin

Publications and source records attributed to Iu P Petrunin.

At least 19 recordsLinked to original sources
PubMed1988

[The phenomenon of HLA antigen modification in meningococcal infection].

212 patients with the generalized forms of meningococcal infection have been examined. The intensity and quality of lymphocytotoxic reaction in the acute phase and the convalescence period of the disease have been analyzed and the blank calculation has been made at different clinical forms of meningococcal infection. The formation of modified tissue antigens at the acute stage of the disease in the presence of intoxication is shown and the probable role of the intensity of bacteremia in this formation is discussed.

Acute Disease↗
PubMed1983

[The role of the population gene pool in meningococcal infection morbidity].

The character of the distribution of HLA antigens in patients with meningococcal infection among Russians and Touvinians was revealed. The markers of susceptibility to meningococcal infection were detected in each national group. These markers were HLA-Bw22 in Touvinians. The gene of susceptibility to meningococcal infection occurred among Touvinians 2.3 times more frequently. This was probably the cause of a higher morbidity rate in meningococcal infection among Touvinians than among Russians.

Child↗
PubMed1981

[Risk of meningococcal infection in children with different hla phenotypes].

A total of 104 children aged 4 months to 13 years with meningococcal infection were examined. For control 600 healthy donors were used. Histocompatibility antigens were determined by the lymphotoxic test. Altogether 36 antigens of the loci, A, B and C were determined. The data thus obtained indicate that the risk of contacting the infection is 6 times greater for persons with Hl A-Bw16 phenotype and 3 times greater for persons with HL A-A12 phenotype than for persons with Hl A-A1 phenotype.

Adolescent↗