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Biomedical subjects

Iu M Gal'perin

Publications and source records attributed to Iu M Gal'perin.

At least 19 recordsLinked to original sources
PubMed1985

[Effect of homeostasis of chyme composition on absorption of its components in the small intestine during natural digestion].

In dogs, even after essential changes of food ingredients, chyme concentration indices, being formed in duodenum, are steadily kept over a comparatively small range of values in the aftermath of intensive exchange between blood and media filling the lumen of gastroduodenal area. The direction of the balance flow for each substance depends both on the substance initial concentration and the ingredients ratio of food. The homeostating of enteral medium seems to assure the relative stability of the substances balance flow filling up internal medium of the organism.

Animals↗
PubMed1985

[Effect of diet on the formation of chyme and the rate of absorption of nutrients during active digestion].

In dogs with multiple fistulae the rate of absorption of nutrients from enteral lumen using different nutrient mixtures, revealed that the composition of chyme at the entrance into small intestine is homeostased within a certain range of values differing from the diet. A considerable increase of some nutrient in the diet leads to an increase of its content in the chyme and to considerable acceleration of absorption from the gastroduodenal part.

Animals↗
PubMed1984

[Enzymes in the mucosal layer of the small intestine].

It has been demonstrated by the methods of histochemical and biochemical examination of the activity of the enzymes that the mucus layer covering the small intestinal wall contains active enzymes (alkaline phosphatase, leucin aminopeptidase IV, saccharase, lactase) and pancreatic enzymes (alpha-amylase and trypsin). Emphasis is laid on the enrichment of the mucus layer with pancreatic enzymes as compared with small intestinal juice. A hypothesis has been advanced according to which the mucus layer undergoes degradation of polymeric and oligomeric substrates, which plays a physiological part in the digestion of nutritive substances and protection of the internal medium against immunoactive biopolymers. The digestion occurring in the mucus layer is proposed to be called mucus digestion.

Alkaline Phosphatase↗
PubMed1983

[Electron microscopic study of 3H-leucine transport between the internal body environment and the enteral environment].

Using electron microscopic autoradiography, a space-time characteristics of 3H-leucine transport, from the enteral to the inner environment, and from blood plasma to the enteral environment, has been given. Some gradient of intracellular leucin accumulation is determined, from the tip cells of a villus to epithelocytes of the basal membrane. Amino acid transport from blood plasma to the lumen of the intestine is accomplished mainly via the cytoplasm and intercellular space of epithelocytes of the villus basement. It is proposed that amino acid transport through membranes of microvilli and through basal-lateral membranes of cells being on various levels along the villus may start at different amino acid concentrations which may be, presumably, to different concentration and different conjugation of enzyme-transport complexes in these membranes.

Animals↗
PubMed1982

[Role of the enterohepatic circulation of endogenous lipids in food lipid absorption].

In preliminarily operated dogs with fistulas in stomach and different portions of the small intestine, the liver-intestinal circulation of endogenous phospholipids and cholesterine aided to form the chimus all the lipid fractions of which were absorbed proportionally. The recirculation of endogenous lipids seems to be one of the physiological mechanisms of lipid absorption from food in the small intestine.

Animals↗
PubMed1981

[Phenomenon of formation of structures in the dense fraction of the enteric milieu when its pH is changed].

Morphological study of the dog duodenum and ileum contents revealed that the food particles of less than 2 mm size constituted not more than 30% of the total volume of the chyme dense fraction. The main part of the dense fraction consists of the gel structures precipitating in the enteral milieu during changes of its pH due to acid content of the stomach. Histochemical reactions of these structures reveal presence of mucopolysaccharides, proteins and lipids. As the surface of these structures is able to adsorb the digestive enzymes, the intensive digestion of small food particles seems to be due to an increase of the enzyme hydrolysis occurring on the chyme dense fraction structures which are being formed during changes of the enteral milieu pH.

Animals↗