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Biomedical subjects

Iu M Belozerov

Publications and source records attributed to Iu M Belozerov.

At least 19 recordsLinked to original sources

[Mental disorders in a pediatric clinic].

In general pediatric clinic 262 children aged 1-15 years with functional hyperthermia, functional disorders of cardiac rhythm (extrasystole, paroxysmal and recurrent tachycardia), arterial hyper- and hypotension, autonomic dysfunctions were examined. 21 children with organic cardiac diseases were examined too. Mental disorders were revealed in all the cases: mono- and bipolar affective disorders (58.1%) as well as affective-dilutional (10.4%) states, primarily in the form of "masked" hypomanias, neurotic and neurotic-like (16.2%), psychopathic and psychopathic-like (7.0%), psychoorganic (3.7%) and epileptiform (4.6%) syndromes. The spectrum of mental disorders was extremely wide--from practical normal (in limits of reactions of personal accentuations or age crisis) to endogenic diseases. Combined treatment including drug therapy, psychotherapy and family correction was quite effective.

Adolescent↗

[Histographic analysis of the heart contraction rate during Holter monitoring of patients with arrhythmias].

Heart rate histograms were analyzed during 24-hour Holter monitoring in patients with cardiac rhythm and conduction disturbances. The profiles of histograms in the most common cardiac arrhythmias: extrasystole, chronic supraventricular reentry tachycardia, atrioventricular block, sinus tachycardia, sick sinus syndrome and those in patients with implantable pacemakers were shown. Approaches to analyzing histograms were defined in Holter monitoring, the histographic analysis was demonstrated to be of value in the comprehensive evaluation of Holter monitoring findings.

Adolescent↗

[Characteristics of the cardiovascular system in children with primary arterial hypotension].

Overall 120 children aged 12 to 15 years with primary arterial hypotension and different variants of the disease course (grave, of medium gravity or mild) were examined. The control group was made up to 50 normal children. The program of the examination included electrocardiography, echocardiography, tetrapolar chest rheography and bicycle ergometry. It has been established that in children with arterial hypotension, the intracardiac hemodynamics undergoes compensatory adaptive reconstruction characterized by the enhancement of contractile and pump functions of the myocardium combined with the increased relaxation capacity. The central hemodynamics is characterized by the lowering of the general peripheral vascular resistance. The functional potentialities of the cardiovascular system decline, manifesting in the form of a decrease of exercise tolerance in association with energy losses necessary for its performance. The use of bicycle ergometry made it possible to delineate dysadaptation reactions of arterial pressure to exercise, modified by hereditary factors.

Adolescent↗

[Characteristics of circadian variability of heart rate during Holter monitoring].

24-hour Holter monitoring of 60 healthy children aged 3 to 15 years provided criteria for assessing the circadian heart rate (HR) variations as a measure of alterations occurred in autonomic heart rhythm control. Specific HR dynamics during their sleep is described, which involves changes in steady-state rhythm and higher dispersion periods associated with the alternation of slow and fast sleep phases. Sex- and age-related HR features are defined during 24-hour monitoring.

Adolescent↗

[Chronic nonparoxysmal supraventricular tachycardia in children and adolescents].

An examination was performed in 111 children and adolescents with recurrent and sustained chronic nonparoxysmal tachycardias (CNPT). ECG and electrophysiological studies showed that ante- and retrograde conduction along the accessory atrioventricular junction was the most common mechanisms of arrhythmia. Holter monitoring revealed a high rigidity of cardiac rhythm in patients with sustained CNPT. Criteria for the development of arrhythmogenic cardiac dilatation were developed. In recurrent CNPT, there was a correlation between the paroxysms of ECG slow-wave activity and the "salvos" of tachycardia and a predominance of vagal effects on the heart. A new approach to the treatment of children with CNPT was proposed, which involved the correction of pathogenetic mechanisms. Indications for the usage of antiarrhythmic agents such as cordarone and a cardiac surgeon's advice were formulated. The efficiency of the therapy was achieved in 82% of the children as shown by a follow-up.

Adolescent↗

[Characteristics of 24-hour ECG and the regulation of cardiac rhythm in adolescents].

Holter 24-hour monitoring was performed in 50 healthy subjects aged 11-15 years. Daily changes and standard values of heart rate (HR), P-R and Q-T intervals, P, R, T wave amplitudes, ST segment displacement were determined. All the patients under study exhibited sinus arrhythmia, pacemaker migration periods, short cardiac rhythm pauses (up to 1.5 s). Three adolescents were recorded to have Degree I atrioventricular block at night, 3 presented with rare (up to 2 per min) supraventricular contraction beats, 1 had a nocturnal transient Wolff-Parkinson-White syndrome. Despite HR at night, there were periods of Q-T interval prolongation. Daily changes in the neurohumoral regulation of the heart and its relation to the occurrence of various electrocardiographic events were determined.

Adolescent↗