Biomedical subjects

Iu M Azizov

Publications and source records attributed to Iu M Azizov.

40 records · Page 3Linked to original sources

PubMedDate not supplied

[Acid-soluble blood glycoproteins in patients with diffuse purulent peritonitis].

The levels of acid-soluble blood plasma glycoproteins (ABP) were compared in patients with diffuse purulent peritonitis and normal subjects. The content of protein and total carbohydrates in the ABP fraction of normal subjects was 0.68 +/- 0.08 and 0.11 +/- 0.02 mg/ml, respectively, with the carbohydrate to protein ratio 0.21 +/- 0.03. In the patients these parameters were, respectively, 1.37 +/- 0.19, 1.09 +/- 0.12, and 0.88 +/- 0.10. Possible mechanisms of accumulation of carbohydrate-enriching ABP in peritonitis patients is discussed. The carbohydrate to protein ratio is proposed to be used for assessment of the status of peritonitis patients and for prediction of the disease course and outcome.

Acids↗

PubMedDate not supplied

[Urea and creatinine kinetics during the continuous hemofiltration of patients with acute kidney failure].

Continuous hemofiltration (CHF) procedures (a total of 33 with overall duration 2495 hours and replacement of 2221 kg of fluid) were conducted in 23 patients (12 males and 11 females) aged 30.5 +/- 2.5 years suffering from severe acute renal failure (ARF). CHF efficacy was judged by the kinetics of urea and creatinine. With parenteral feeding the patients received protein and amino acids 1.2-1.5 g/day/kg b.m. The death of 13 patients resulted from sepsis, hemorrhage, shock, adrenal insufficiency. The filtration speed 15.6 +/- 0.6 (7-34) ml/min allowed replacement of 21.7 +/- 1.3 (8-49) kg or 0.49 +/- 0.03 of body fluid a day. The highest rate of hemofiltration was used on day 1, this reducing plasma urea from 35.7 +/- 2.5 (7.5-55.0) to 27.5 +/- 2.0 mmol/l (p < 0.05) and creatinine from 742 +/- 77 (182-1800 to 539 +/- 44 mumol/l (p < 0.05). Subsequently urea and creatinine were maintained in the plasma at the levels 26.8 +/- 1.0 mmol/l and 539 +/- 73 mumol/l, respectively. Urea eliminated with the filtrate amounted to 591 +/- 53, creatinine 13.5 +/- 4.0 mmol or 0.49 +/- 0.02 and 0.65 +/- 0.07 of the overall pools, respectively. In anuria urea generation reached 525 +/- 35 (108-1071) mmol/day, that of creatinine 9.6 +/- 1.4 (1.2-14.0) mmol/day, being on the average less than filtrate elimination of these substances. It is believed that CHF contributes to balanced treatment of severe ARF in spite of parenteral introduction of large quantities of protein and amino acids.

Acute Kidney Injury↗

PubMedDate not supplied

[Mechanisms of action of intravenous helium-neon laser irradiation in anesthesia].

Intravenous exposure to He-Ne laser was added to the anesthesiologic schemes of 26 patients during surgery on the intestine. The reference group consisted on 23 patients. Comparison of the blood antioxidant activities (from the levels of ceruloplasmin and transferrin) and the endogenic intoxication levels (from the medium molecule test) showed that intravenous laser exposure at a wavelength of 630 nm stabilized the blood antioxidant activity and prevented the development of endogenous intoxication.

Anesthesia↗

PubMedDate not supplied

[The concentration of end products of purine metabolism as possible signs of tissue hypoxia in critically ill surgical patients].

The study was performed on 26 critically ill patients with hemorrhagic pancreonecrosis and disseminated suppurative peritonitis. Central hemodynamic and oxygen transport parameters have been determined in all the patients. To assess the degree of tissue hypoxia end products of ATP catabolism (hypoxanthine, xanthine, and uric acid) have been studied. All the studies were performed at various stages of correction of volemic disturbances and oxygen transport function. It has been established that an increased blood plasma level of hypoxanthine and xanthine may serve as an additional criterion of tissue hypoxia in critically ill surgical patients. Changes in hypoxanthine, xanthine, and uric acid concentrations and oxygen transport parameters can be used to assess changes in the functioning of the microcirculatory bed.

Adenosine Triphosphate↗