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Biomedical subjects

Iu L Perov

Publications and source records attributed to Iu L Perov.

51 records · Page 3Linked to original sources
PubMedDate not supplied

[Experience at cooperation between the Moscow Municipal Center of Pathology Research and the Chair of Pathology of the Russian Medical Academy of Postgraduate Training].

Pathology service in Moscow, unlike in other cities of Russia, is not centralized and consists of 57 pathology departments of hospitals for adults and 5 departments of children hospitals of municipal subordination; 30 federal pathology departments of hospitals, 20 departments and laboratories of research medical centers and 5 pathology chairs of medical institutes. In spite of high professional levels of the pathologists, the lack of a centralized city service is a negative aspect. Cooperation between Moscow City Pathology Center and Chair of Pathology of Russian Medical Academy for Postgraduate Education illustrates positive trends to consolidation of Moscow pathologists.

Academies and Institutes↗
PubMedDate not supplied

[Pathohistological diagnosis of precancerous conditions and cancer of the breast].

It is suggested to improve histopathological diagnosis on the basis of mean ploidy of cell clones characterising separate stages of carcinogenesis. Additional ploidometric analysis of sections stained by Felgen enables differential diagnosis of benign (hyperplastic lesions and mild neoplasia) with malignant stages of carcinogenesis (grave intraepithelial neoplasia, carcinomas) in the breast.

Adult↗
PubMedDate not supplied

[Using telepathology for remote pathoanatomical diagnostics].

The experience accumulated in 2000-2002 in the department of pathology of the central clinical hospital of President Administration Medical Centre on the use of telepathology for distant anatomopathological diagnosis is reviewed. Multilevel consulting-diagnostic telepathological network having local (intrahospital and city), federal and international levels was created in the scope of the departmental telemedical project. The results of the use of removed telediagnosis for urgent histological studies on frozen sections indicate the absence of differences between this method and conventional optical diagnosis.

Computer Communication Networks↗
PubMedDate not supplied

[A method of determination of the accuracy of morphological diagnosis of surgical and biopsy material].

The accuracy of morphological diagnosis of 281 surgical samples and biopsy material was analyzed including 253 intrasurgical biopsies on frozen and paraffin sections and 26 television (out of sight) consultations in the "off-line" regime with subsequent control optical microscopy of paraffin sections. The indices of specificity, correspondance and sensitivity allow to have more objective assessment of the quality of life-time morphological diagnosis and can be considered as an obligatory component of annual reports of pathology departments and reports of clinical pathologists at professional certification.

Biopsy, Needle↗
PubMedDate not supplied

[Pathomorphology of the kidneys in hemolytic-uremic syndrome in children].

The kidneys were studied morphologically in 64 cases of hemolytic-uremic syndrome (HUS) in children aged from 17 days to 4 years. Three variants of the kidney alterations are distinguished depending on the duration of acute renal failure (ARF): early, late and delayed alterations. Early alterations were observed if ARF lasted for 1-10 days and were characterized by glomerular thrombotic microangiopathy with disturbance of the nephron proximal part function resultant from microcirculatory damage. Late kidney alterations (11-20 days of ARF) consisted of glomerular thrombi fibrinolysis, development of mesangial cell proliferation and mesangiolysis, proximal tubular epithelium regeneration and the appearance of nephrohydrosis resulting from the distal nephron part obstruction by hyalin cylinders. Delayed alterations (21-62 days of ARF) manifested with predominant atrophic and sclerotic processes. The first variant corresponded to the acute course of HUS while the two last variants to the subacute one.

Acute Kidney Injury↗
PubMedDate not supplied

[Pathomorphology of extrarenal alterations in hemolytic-uremic syndrome in children].

Extrarenal alterations were studied in 64 cases of hemolytic-uremic syndrome (HUS) in children aged from 17 days to 4 years. Three groups are distinguished depending on the presence of acute renal failure (ARF) or induced by its treatment. Thrombotic microangiopathy which was present in the acute stage of the disease in the colon, pancreas, brain, spleen, liver represented the first group. The second group included extrarenal alterations associated with ARF-hyperhydration of organs and tissues with accumulation of the liquid in the serous cavities, dilatation of the heart cavities and myocardial hypertrophy, brain hemorrhages, hemorrhagic diathesis, immunodepression of immunogenesis organs. The third group of the extrarenal alterations induced by the ARF treatment was characterized by infectious and iatrogenic complications.

Acute Kidney Injury↗