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Biomedical subjects

Iu Kh Sarkisian

Publications and source records attributed to Iu Kh Sarkisian.

At least 19 recordsLinked to original sources

[Automation of gamma-ray teletherapy].

A system of automated control Aspect-2 was developed for automation of gamma-beam therapy on units of the Rokus series. The system consists of the following hardware and software complexes: a complex of preirradiation preparation "Centrator-imitator"; a complex Accord for anatomotopographic data coding; a software complex and a gamma-therapeutic complex Rokus-AM. The Centrator-imitator and Rokus-AM complexes are fitted out with built-in microcomputers with specially developed systemic software. The Rokus-AM complex has automatic punch tape programmed control of 9 degrees of freedom of the gamma-unit and treatment table and ensures 5 modes of irradiation: positional, rotating, rotating-convergent, sectoral rotating-convergent and scanning.

Computer Systems↗

[Effect of multi-fractionation in radiotherapy of rectal cancer].

The paper is concerned with the substantiation of multifractionated gamma-beam therapy and the results of the use of this regimen in radiotherapy of rectal cancer. The authors have proposed the following scheme of irradiation: a single focal dose of 2 Gy is delivered not once a day as in routine fractionation but twice a day with a 4-hour interval. A radiotherapeutic course has been divided into 3 stages of 5 days each with 5-day intervals in-between. The course total focal dose was 60 Gy, "time-dose-fractionation" factors--140, the equivalent total dose--83 Gy. Statistically significant improvement of immediate results and a decrease in the number and expression of radiation reactions were noted. Earlier (as compared to routine fractionation) appearance of a symptomatic effect and the reduction of a time-period of a radiotherapeutic course in bed-days by 30% were also noted.

Adenocarcinoma↗

[Combined gamma-therapy of rectal cancer using movable radiation sources in intracavitary irradiation].

The authors present a technique of concomitant radiotherapy of rectal cancer using 60Co movable sources of the Agat-B unit for contact irradiation. The paper is illustrated with the schemes of radiation sources in relation to tumors and pictures of dose fields formed by various radiation sources and positions as well as their time intervals in each position during a therapeutic session. The results of treatment of patients in the main group (47 persons) and in the control group when the patients received gamma-beam therapy only (45 persons) are also given in the paper. Two-year survival rates have shown significantly improved long-term results in the main group. The new method is recommended for practical use as a variant for extended indications to concomitant radiotherapy of rectal cancer and for improving its results.

Adult↗

[Use of dibunol in treating radiation injuries to the skin and mucosa].

The authors present the results of the use of dibunol in the form of liniment (1-10%) for the treatment of radiation cystitis and rectitis resulting from radiation therapy of small pelvic tumors, epidermitis and epithelitis that develop in the course of treatment of skin and lower lip tumors. A high efficacy of the drug in the therapy of radiation injury has been shown in 212 patients.

Aged↗