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Biomedical subjects

Iu K Danis

Publications and source records attributed to Iu K Danis.

18 recordsLinked to original sources
PubMed1989

[A program for the prevention of diabetes mellitus in Lithuania].

The Programme on Diabetes Mellitus Control is a constituent part of Integrated Programme on Chronic Non-infectious Diseases Control. The epidemiological evidence has demonstrated the high prevalence of deranged carbohydrate metabolism in the republic. Registers of carbohydrate metabolism disorders were created for the children's population of the Republic and the adult population of Kaunas and two agricultural-industrial regions. A school for diabetic patients and the society 'Insula' were organised. The research-practical programme is implemented in stages.

Adult↗
PubMed1985

[Performing and interpretating the glucose tolerance test].

Certain conditions like drug use, diet, physical activity, etc., must be adhered to while running the glucose tolerance test. The Second WHO Expert Committee on Diabetes Mellitus (1979) suggested that the oral glucose tolerance test should be carried out with 75 g of glucose (for children 1.75 g/kg of ideal body mass but not over 75 g). During epidemiological investigations a glucose solution should be prepared by a constant concentration method using an areometer. Schematic interpretation expressed in the rectangular coordinate system reflecting diagnosis was offered for the estimation of findings.

Adult↗
PubMedDate not supplied

[Relative number of B-lymphocytes in endocrine opthalmopathy in patients with diffuse toxic goiter].

The number of B-lymphocytes was counted in 69 patients with diffuse toxic goiter (DTG) using a new method. The relative number of B-lymphocytes was investigated before therapy, one year and 2 years after it. The patients were divided into 2 groups (48 patients with endocrine ophthalmopathy and 39 patients without it). The investigation has shown that in the patients without endocrine ophthalmopathy the relative number of B-lymphocytes did not differ from control values, whereas in the patients with endocrine ophthalmopathy their number was elevated. These differences suggested an idea of the involvement of B-lymphocytes in the process of endocrine ophthalmopathy, that was confirmed by positive correlation (r = 0.38, p less than 0.001) between the relative number of B-lymphocytes before therapy and a degree of endocrine ophthalmopathy in one year. Thus, the relative number of B-lymphocytes before therapy can serve a marker of an outcome of endocrine ophthalmopathy.

B-Lymphocytes↗
PubMedDate not supplied

[Vitamin E and malondialdehyde in the blood serum of thyrotoxicosis patients].

The concentrations of vitamin E and malonic dialdehyde (MDA) were investigated in the blood serum of 146 patients with diffuse goiter of various degree of severity and in 35 controls with diffuse and nodular goiter without thyroid dysfunction. Vitamin E and MDA concentrations in patients with mild thyrotoxicosis did not differ from that in the controls. Vitamin E concentrations in patients with moderate and severe types of thyrotoxicosis were notably decreased and MDA concentration was elevated. The data on decreased vitamin E concentrations and increased MDA concentrations indicated vitamin E insufficiency in these patients. This fat-soluble antioxidant is recommended for multimodality therapy of thyrotoxicosis.

Adolescent↗
PubMedDate not supplied

[The clinical picture, hormonal disorders and humoral immunity in patients with autoimmune thyroiditis].

Altogether 93 patients with autoimmune thyroiditis were investigated. A great variability of the functional clinical symptomatology (from thyrotoxicosis up to manifest hypothyroidism) was revealed. Subclinical hypothyroidism was detected in a majority of patients. In some patients the clinical symptoms of thyrotoxicosis were combined with euthyroidism or subclinical hypothyroidism basing on the findings of the hormonal investigation which should be taken into account while choosing therapeutic tactics. Patients with autoimmune thyroiditis demonstrated a preserved circadian rhythm of cortisol secretion. Adrenocorticotropin-zinc-phosphate testing has shown good functional adrenocortical reserves; cortisol secretion did not depend on thyroid function nor did it differ from the indicator in the control group.

Adolescent↗
PubMedDate not supplied

[Effect of therapy on the levels of immunoreactive calcitonin and parathormone in patients with autoimmune thyroiditis].

Altogether 18 female patients and one male patient with autoimmune thyroiditis aged 17 to 57 were investigated before and during thyroidin therapy. A basal raised level of immunoreactive calcitonin (iCT) was revealed in 4 patients, that of immunoreactive parathormone (iPTH) in 11 patients. The authors discussed the causes of the elevation of iCT and iPTH levels in patients with autoimmune thyroiditis. A transient character of a rise of the content of these hormones was noted. The authors suggested that in raised iCT and iPTH levels assessment of C-cell and parathyroid function should be repeated in patients with autoimmune thyroiditis after compensation of the main disease.

Adolescent↗
PubMedDate not supplied

[Effect of human somatotropin on metabolism in hypothalamo-hypophyseal nanism patients].

The effect of pharmacopoeic human somatotropin (HS) produced by the Kaunas plant of endocrine preparations, on the proteic, lipid, carbohydrate and mineral metabolism was studied in 40 patients with hypothalamohypophyseal nanism (HHN). The experiments were performed before treatment on an empty stomach, 4 hs after HS administration in a dose of 4 I. U. and during the course of treatment (with 1-2 or 3-4 monthly intervals). The HS administration resulted in the increase of urea, phosphorus and alkaline phosphatase levels, decreased those of beta-lipoproteins, potassium and sodium and caused the redistribution of proteic fractions in the blood of HHN patients. Simultaneous reduction of the urea, creatinine and phosphoric excretion in lime with enhanced urinary excretion of potassium was observed. During a long-term intermittent HS therapy no changes were revealed in carbohydrate metabolism in HHN patients.

Adolescent↗