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Biomedical subjects

Iu Iu Bredikis

Publications and source records attributed to Iu Iu Bredikis.

At least 19 recordsLinked to original sources

[The value of digital-analog Holter monitoring systems in the noninvasive diagnosis of heart rhythm disorders].

By using the Custo Mega ECG monitoring system as an example, the value and efficiency of digital analog Holter monitoring systems in the non-invasive diagnosis of cardiac arrhythmias have been analyzed. The findings suggest that the Holter monitoring system produces high reliability, sensitivity (80.8-100%), and specificity (70.9-100%) in analyzing arrhythmic phenomena on ECG as compared to other Holter monitoring systems and electronic pacemakers.

Analog-Digital Conversion↗

[Ablation of ventricular tachycardia in thoracotomy without artificial circulation].

Seventeen patients were operated on for ventricular tachycardia (VT). Closed heart radical surgeries destroying the arrhythmia substrate were made without employing extracorporeal circulation. A VT episode was inducible in 16 (94%) patients for VT intraoperative mapping. The tachycardia substrate was removed by cryodestruction, cryoisolation or both. A special cryoprobe was introduced into the ventricular cavity by placing the purse-string suture at its apex. VT paroxysms completely disappeared in 12 (70.6%) and could be arrested by medications in 2 (11.8%). Three (17.6%) patients had recurrent VT episodes following a surgery. One (6%) patients died on day 7 of postoperation. The method proposed impairs no heart physiological activity, which facilitates inductions of an episode and its mapping during a surgery. The closed heart surgery enables the method to be applied in patients at a high risk for surgeries by employing extracorporeal circulation.

Adolescent↗

[Surgical treatment of Wolff-Parkinson-White syndrome: analysis of the methods and results].

The authors analyse the outcomes of surgical management in 400 patients with the Wolff-Parkinson-White syndrome who had been operated on in the All-Union Centre for Surgical treatment of Severe Cardiac Arrhythmias and Electrocardiostimulation. Unique surgical procedures were applied, which made it possible to perform cryodestruction of accessory atrioventricular pathways, without resorting to an extracorporeal circulation and without opening heart cavities. The procedures are demonstrated to be not inferior to operations using extracorporeal circulation. It is concluded that patients with the Wolff-Parkinson-White syndrome should be operated on under natural circulation, in particular if they have a concomitant abnormality as a risk factor for employing extracorporeal circulation.

Adult↗

[Laser destruction of the atrioventricular bundle using the cardiac endoscope].

The results of experiments where endoscopes of various makes were introduced into the right atrium under thoracotomy or transvenously are reported. After visual determination of the A-V node zone, laser coagulation was performed by Nd-YAG laser until complete A-V block was achieved. Various methods of laser cardiac endoscopy application are discussed. Laser destruction of the heart conduction pathways through a cardiac endoscope with a polyurethane balloon appears to be the most convenient technique.

Animals↗

[Cryogenic effect on the coronary arteries in animal experiments].

The present study was designed to examine both acute and chronic effects of cryothermia on the coronary arteries in the experimental model. Microscopic examination has revealed coronary intimal hyperplasia in the majority of coronary arteries at the site of cryogenic lesion. In some cases cryothermia was complicated by arterial thrombosis.

Animals↗

[Transposition of the pacemaker in the right atrium during stimulation of the vagus nerve in the dog].

The heart rate and intraatrial latencies between epicardial electrograms from three sites of the right atrium have been studied during vagal stimulation in open-chest dogs. It has been shown that alterations of latencies started at a certain cardiac cycle length irrespective of pacing frequency. A transitional process of changes from a steady latency value in the control to another steady value during vagal stimulation has been observed. The transitional process has been simulated in experimental procedure in which two sites of the right atrium were paced at close and constant frequencies. To interpret the results obtained one-dimensional model of the sinus node has been constructed. According to the model, pacemaker shift within the sinus node results from a competition between two foci of automaticity with close intrinsic frequencies.

Animals↗

[Ambulatory electrophysiological diagnosis of heart rhythm disorders].

A noninvasive method of electrophysiologic investigation (EPI) making use of programmed esophageal electrostimulation of the heart has been developed on the basis of EPI carried out in 2158 inpatients (including 1273 procedures involving esophageal electrostimulation of the heart). Its introduction in an outpatient cardiologic clinic in Kaunas made it possible to investigate 522 patients with heart rhythm disorders in 1985 alone. Effective antiarrhythmic therapy could be selected for 389 (74.5%) patients on an outpatient basis, while 133 (25.5%) patients had to be referred to hospital for more detailed EPI, implantation of an indwelling pacemaker or radical surgery. It is demonstrated that an adequate antiarrhythmic treatment can be selected on an outpatient basis.

Adolescent↗

[Surgical treatment of children with ectopic atrial tachycardia].

Up-to-date electrophysiologic investigations of the heart, carried out in 212 children with arrhythmias, demonstrated a focus of ectopic atrial tachycardia in 21 (9.9%); 17 of those underwent long-term treatment (up to 10 years) with antiarrhythmic drugs. Kordaron produced a positive effect (discontinuation of the attacks) in 1 case only. Combined use of several antiarrhythmic drugs controlled the frequency of tachycardia in 4 patients. Signs of dilatation cardiomyopathy were in evidence in 60% of children with permanent ectopic tachycardia. Seven of 12 patients who failed to respond to medication were eventually subjected to radical surgery. All but one were discharged from hospital without additional medication and with normal heart rhythm. One child developed groups of extrasystoles generated by the lower right-atrial portion during the 2nd week after surgery. They diminished and eventually disappeared after a supportive digoxin treatment. Surgery is therefore regarded as an effective and radical treatment for ectopic atrial tachycardia in children.

Adolescent↗

[Use of differential methods for analyzing electrocardiograms in the diagnosis of supraventricular arrhythmia].

Differential-gain ECG (DG-ECG) recordings were made to investigate the mechanism of tachyarrhythmias. The study comprised experimental and clinical series. Experimental findings demonstrated two types (local and circulatory) of vulnerability manifested during induced tachyarrhythmia. Differential-gain ECG recordings were used in the clinical series to specify experimentally-demonstrated mechanisms of tachyarrhythmias: differentiate focal and circulatory excitation sources and specify the localization of both the sources of tachycardia and additional atrioventricular bundles associated with the ventricular pre-excitation syndrome.

Adult↗