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Biomedical subjects

Iu I Vorob'ev

Publications and source records attributed to Iu I Vorob'ev.

At least 19 recordsLinked to original sources

[Cancer of maxillary mucosa (symptoms and diagnosis)].

The experience in diagnosis of maxillary mucosa cancer in 222 patients is reviewed. Male and female mortalities were the same. Mean age of the men was 59.9+/-13.1 years, of the women 69.4+/-15.2 years. 211 patients were admitted to hospital for the first time and 11 with relapses after conducted treatment. The disease history in 121 patients varied from 1 week to 3 months from the disease onset, in 90 (45.6%) patients--from 3 months to 1 year. Patients with stage 3 (n=141) and stage 01 (n=51) made up 90.9% of all the cases. Stage 2 was diagnosed in 16 patients and stage 1--in 3 patients. Diagnostic potential of the conventional X-ray study, computed and magnetic resonance tomography in diagnosis of maxillary cancer is shown.

Adult↗

[Removal of teeth in patients with malignant maxillofacial tumors during different periods of radiotherapy].

Surgical treatment (tooth removal) of 63 patients with malignant maxillofacial tumors was carried out before, during and 6 months after radiotherapy. A total of 113 teeth were removed because of chronic foci of infection in the periapical tissues. The results of dynamic observations indicate that the risk of complications in this patients population is not high if the rules of tooth removal are strictly adhered to.

Adult↗

[Radiotherapy of lymphosarcoma of the major salivary glands].

Twenty patients with cytologically verified diagnosis of lymphosarcoma of the major salivary glands (15 with lymphosarcoma of the parotid gland and 5 with lymphosarcoma of the submandibular gland) were treated by radiotherapy. Twelve patients presented with stage I E, 7 with stage II E, and 1 with stage IV EO. Metastases in the cervical lymph nodes were diagnosed in 7 patients. Total focal doses for the primary tumor and metastases were 30-40 Gy during 3-4 weeks. The observation of 2-4 years showed that radiotherapy led to cure of 12 (60+/-15.4%) patients. No trends to relapses and generalization of the process were observed. No preventive exposure of the lymph discharge zones was carried out.

Aged↗

[The clinical picture, diagnosis and radiation treatment principles in cancer of the buccal mucosa].

Diagnosis and treatment of 228 patients with cancer of the buccal mucosa is analyzed. There were 130 women and 98 men aged 65 years on average. 218 were primary patients and 10 with relapses. Squamous-cell carcinomas with hornification predominated: 217 cases (95%). Adenocarcinoma was diagnosed in 8 (3.5%) and poorly differentiated cancer in 3 patients. Metastases to the regional lymph nodes were detected in 25% cases. For cosmetic reasons, radiotherapy (oral x-ray therapy, interstitial method, long-distance gamma beam therapy) was the method of choice.

Adenocarcinoma↗

[Cancer metastases to the cervical lymph nodes in an unknown primary location of the tumor].

Out of 120 patients hospitalized with the diagnosis of metastases to the cervical lymph nodes and unknown primary location of the tumor, tumors were detected in 29 and lymphosarcoma in 10. In 24 (82.7%) patients the tumor was located in the upper respiratory tract and gastrointestinal tract. Malignant tumors of the naso- and stomatopharynx and vestibular part of the larynx most often metastasize into the lymph nodes. Radiotherapy was administered to all 81 patients with metastases and unknown location of the primary tumor and to 10 patients with lymphosarcoma of the cervical lymph nodes. The protocol of radiotherapy took account of the site of the metastases and probable primary tumor. A radical course provides cure in 15% of cases, as shown by follow-up of at least 2 years.

Adult↗

[The radiation therapy of skin cancer of the face].

Results of three-year radiotherapy are assessed in 586 patients with skin cancer, with tumors localized on the skin of the face in 484 of these. The results of treatment were found to depend on the histological structure of the tumor and disease stage: 100% cure was attained in patients with basal-cell carcinomas and T1 stage, whereas only 7% of patients with T4 stage were cured; in patients with squamous-cell carcinoma these figures were, respectively, 96.2 and 10%.

Adult↗

[The characteristics of managing cancer patients during gamma teletherapy].

Gamma-beam therapy of cancer patients is accompanied by general and local radiation reactions, their degree depending on numerous factors (a tumor site, an area of irradiated tissues and a value of a total absorbed dose). Preventive and therapeutic measures during radiotherapy allow the reduction of severity of a course of general and local radiation reactions.

Gamma Rays↗

[Metastasis to the vascular tunic of the eye].

The author has summed up his experience in the diagnosis and radiation therapy of 6 patients with breast cancer (5) and lung cancer metastases to the vascular coat of the eye. The initial and leading symptoms are increasing impairment of vision. In 3 patients metastases to the eye developed against a background of tumor generalization. gamma-beam therapy at a total focal dose of 30 Gy within 10 days of irradiation improved vision in 4 patients.

Adult↗

[Magnetic resonance tomography in evaluating the efficacy of the radiation therapy of tumors in the upper respiratory tract].

Analysis of the diagnostic potentialities of MR-tomography in the assessment of radiotherapeutic efficacy was performed in 11 patients (malignant tumors of the upper respiratory tract in 10 and juvenile nasopharyngeal angiofibroma in one). Repeated investigation was performed after abatement of local radiation reactions (usually after 4-8 weeks). MR-tomography permitted the assessment of the state of the accessory sinuses of nose, the detection of a residual tumor, and the differentiation between tumors and inflammatory changes of the mucosa. In one case radiotherapy resulted in the regeneration of posterolateral wall of the maxillary sinus.

Evaluation Studies as Topic↗

[Radiation therapy of disseminated laryngopharyngeal cancer].

The paper is concerned with the long-term results of therapy of 68 laryngopharyngeal cancer patients at advanced stages. The 3-year survival after a radical split course of gamma-beam therapy was 29 +/- 7.7%. A degree of tumor cell differentiation made no effect on therapeutic results.

Adult↗

[The possibilities of x-ray study in assessing the results of the radiation treatment of laryngeal cancer].

The paper is devoted to comparing laryngoscopy findings and the results of x-ray investigation in its time course (prior to, during and after radiation therapy) in 65 laryngeal cancer patients. Both methods are mutually complementary, and thorough comparison of their results helped to overcome diagnostic difficulties. The basal point and spreading of exophytic supralaryngeal tumors can be determined by x-ray only. The greatest diagnostic difficulties occur after therapy to differentiate between postradiation mucosal edema and a tumor relapse.

Adult↗