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Biomedical subjects

Iu A Vlasov

Publications and source records attributed to Iu A Vlasov.

At least 19 recordsLinked to original sources

[Myocardial blood flow in different regions of the heart in patients with ischemic heart disease before and after revascularization].

Laser doppler flowmetry was used for the intraoperative study of myocardial blood flow before and after revascularization in 116 patients with 2-3 vessel coronary artery disease and class II-IV angina. In patients without myocardial infarction, with microfocal myocardial infarction, or operated early after myocardial infarction revascularization caused no significant increase of myocardial blood flow. In patients with macrofocal infarction surgery was associated with significant increase of myocardial blood flow. Efficacy of revascularization could be assessed by lowering of flow gradients between various regions of the myocardium.

Adult↗

[Blood oxygen saturation in various regions of the circulatory system in healthy persons].

The gaseous composition of the blood has been determined in cardiac cavities and major vessels in 180 practically healthy individuals aged from 1 to 30 years, during diagnostic catheterization of the heart. Physiological norms of gaseous composition of the blood in cardiac cavities and in the major blood vessels have been determined. Blood saturation with oxygen in the identical cardiac cavities and the major blood vessels are the same in men and women. The arterial blood having oxygenation below 93% is considered hypoxaemic. Normal figures of oxygenation for venous blood are from 75-84%. Exponential decrease of blood oxygenation with age (arterial and mixed venous) is roughly the same, due to this the arteriovenous difference of oxygenation at rest remains constant and is roughly equal to 20%. Minimum arterio-venous difference in oxygenation is 10%, maximum 40%.

Adolescent↗

[ABO and Rh blood groups in cardiovascular pathology].

A relationship between erythrocytic antigens of the ABO and Rh blood systems and cardiovascular pathology was revealed by comparing the distribution of blood groups in 13,175 patients and 7,800 donors. Prevalence of A gene and Rh+ phenotype in congenital and acquired heart diseases and ischemic heart disease was found. The frequency of B gene is increased in patients with acquired heart diseases.

ABO Blood-Group System↗

[Evolution of lesser circulation hypertension in patients with congenital heart defects based on the example of an interventricular septal defect].

The results of direct pressure measurement in pulmonary circulation in 452 patients with ventricular septal defect (216 males and 236 females), whose age ranged from 12 months to 37 years, were analysed. The findings of diagnostic catheterization of the heart in 150 practically healthy persons 12 months to 40 years of age were used to elaborate the normal values of pressure in pulmonary circulation. The results of pressure measurement in pulmonary circulation repeated at intervals of 1 to 6 years in 46 patients with ventricular septal defect, 18 months to 23 years of age, were analysed. Reverse evolution of pressure in pulmonary circulation after surgical rehabilitation was followed up in 85 patients in 1, 2, 3, 5, and 7 years after the operation. At the age of 12 months to 7 years, systolic pressure in the right ventricle and pulmonary artery comes down to a possible minimum due to expenditure of the adaptational reserve. In large ventricular septal defects, however, the organism proves incapable of reducing the pressure in the early and first periods of childhood as a rule, and so the pressure increases throughout life.

Adolescent↗

[Study of the pulmonary vessel reaction to administration of carbon dioxide and nitroglycerin in congenital heart defects complicated by high pulmonary hypertension].

The results of functional pharmacological tests with nitroglycerine and carbon dioxide gas are presented for patients with congenital heart diseases and pulmonary hypertension, as shown during right heart catheterization. It was established that nitroglycerine, taken sublingually, does not produce any direct effect on the pulmonary artery pressure, and the delayed changes in haemodynamics are a consequence of the altered regimen of pressure in the general circulation. When carbon dioxide gas was administered into the pulmonary artery, it proved to produce a direct effect upon the receptors of the pulmonary arterial bed. However, along with the hypotensive effect, in some cases the carbon dioxide gas increases the pressure in the pulmonary artery due to the embologenic effect of the gas bubbles. Both agents affect the arterial pressure irrespective of the patient's age, the nature of the heart disease, and the degree of pulmonary hypertension.

Adolescent↗