Biomedical subjects

Ignacio Rubio Tortosa

Publications and source records attributed to Ignacio Rubio Tortosa.

4 recordsLinked to original sources

PubMed2006

[Leydig cell tumor: our experience. Bibliographic review].

OBJECTIVES: To report the case-series of Leydig cell tumors diagnosed at our center, and to perform a bibliographic review on the topic. METHODS: Retrospective review of the clinical records of all patients with the diagnosis of Leydig cell tumor in our center over the last 12 years. We evaluated the clinical, diagnostic and therapeutic features, as well as outcomes. RESULTS: Four patients were diagnosed and treated in our department over this period. Mean patient age of the time of diagnosis was 51 years. Each of our cases have a different presentation. The two patients who underwent sperm analysis had azoospermia. None of the cases showed anomalous hormonal studies. Seventy-five percent of the cases showed ultrasound signs compatible with testicular neoplasia. In all of them surgical treatment was undertaken (inguinal orchyectomy); one of the patients underwent chemotherapy due to metastasis, having a good response. Mean follow-up is 76 months. CONCLUSIONS: It is a rare testicular tumor. Inguinal orchyectomy is the treatment of choice. Its good outcome is remarkable.

Adult↗

PubMed2006

[Fournier's gangrene].

OBJECTIVES: We report a retrospective review of the case series of Fournier's gangrene treated in our department from November 1996 to October 2004. METHODS/RESULTS: We studied nine male patients with ages between 21 and 85 years (mean 55 years). 66% of the patients had associated risk factors, and the underlying cause was identified in 56% of the cases. Mean hospital stay was 21 days and two of the patients died from the disease. CONCLUSIONS: Fournier's gangrene is an infection with a very fast evolution, producing necrotizing fascitis of the external genitalia and perineum. It has a high mortality rate, mainly if diagnosis and treatment are deferred. This last includes wide spectrum antibiotic coverage, surgical treatment with debridement and drainage, and, in many cases, a second surgical intervention for reconstructive plasties.

Adult↗

PubMed2006

[Bladder leiomyosarcoma. Case report].

OBJECTIVE: We report a new case of bladder leiomyosarcoma in a young female patient. We review its features and different treatment options. METHODS: The patient underwent neoadyuvant chemotherapy and surgical excision. RESULTS: A partial response was achieved with neoadyuvant chemotherapy and remains still alive 60 moths after radical cystectomy CONCLUSION: Despite the poor prognosis of this disease, multimodal treatment may improve results. Neoadyuvant chemotherapy and subsequent radical excision could be a good combination therapy for these aggressive tumors.

Adult↗

PubMed2005

[Ureteral actinomycosis. Case report].

OBJECTIVES: To report one case of pseudotumoral lesion of the iliac ureter with obstructive uropathy leading to loss of function of the renal unit. METHODS: 66-year-old male being studied for BPH who presents with a self-limited monosymptomatic hematuria. RESULTS: Renal ultrasound detected grade II pyelocaliectasis of the right kidney. IVU showed absence of function of the right kidney. Urine cytology was consistent with low-grade transitional cell carcinoma. Percutaneous nephrostomy was performed confirming irreversible function loss. Antegrade pyelography showed a filling defect in the right iliac ureter. Radical nephroureterectomy with bladder cuff was carried out with good results. Pathology reported chronic pyelonephritis and parietal inflammatory lesion of the ureter obliterating the lumen with inflammatory infiltrates, urothelial erosion and presence of actinomyces. CONCLUSIONS: Actinomycosis is a chronic bacterial infection, with A. israeli being the most common pathogen. It is part of the normal flora of the oral cavity and GI tract, and cervical-facial region is the most frequent clinical involvement (60% of the cases). Urinary tract infection is exceptional. No other focus was found in the long-term follow-up.

Actinomycosis↗