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Biomedical subjects

I V Stupin

Publications and source records attributed to I V Stupin.

At least 37 records · Page 2Linked to original sources
PubMed1988

[Use of dibunol and delagil in the treatment of acute pancreatitis].

The effect of Dibunol and Delagil on the course of experimental pancreatitis was studied in experiments in 80 rats and 36 dogs. The intravenous injection of the drugs was shown to decrease lethality of the animals. Control of biochemical parameters has revealed decreased activity of amylase, lipase, trypsin and malonic dialdehyde, normalized level of superlight luminescence of blood plasma. A good medical effect was obtained in 15 patients with acute pancreatitis.

Acute Disease↗
PubMed1987

[New textile vascular prostheses made of polymer composition materials].

Functional properties of blood vessel prostheses to large degree depend on the longitudinal elasticity of their walls. Theoretical foundations for designing the physico-chemical properties of prostheses walls were worked out, and special methods and measuring apparatuses. New types of vascular textile prostheses make it possible to model biological tissues. The prostheses walls are a composition of polymers of several types of threads differing to large degree in their elasticity. Comparative theoretical and experimental studies on natural blood vessels, blood vessel prostheses (of traditional threads) and new textile prostheses showed that the last mentioned, as far as their elasticity in concerned, are most close to the requirements and that they have good functional properties.

Animals↗
PubMed1987

[Effect of plasma flow on the regeneration of skin wounds and body reactivity].

The local application of plasma flow to postsurgery wounds in rabbits has revealed accelerated wound healing, reduced perifocal inflammation, the appearance of great numbers of phagocytes and islands of epithelial cells in the wound and certain stimulation of hemopoietic body function. The suppression of free-radical oxidation was accompanied by the activation of the metabolic processes. All this justifies an attempt to apply "plasma methods" in the clinical practice for the treatment of long-healing wounds.

Adaptation, Physiological↗
PubMed1986

[Approaches to the control of lymphogenic metastatic spread of tumors].

Lymphopoiesis stimulating drugs were injected into the blood of rabbits bearing Brown-Pearce transplantable tumor. It was found that treatment with mannitol targeted on osmoregulation mechanisms and terrilytin--on blood and lymph coagulation intensified the lymphogenic migration of tumor cells. When used in an experimental series involving endolymphic transplantation of tumor cells, the said drugs promoted tumor cell passage from lymph to blood, which resulted in an increased number of metastasis-bearing animals. It was also found that the promoting effect may be counteracted by preliminary endolymphic injection of a fat-soluble antitumor preparation. Lymphopoiesis and lymph flow stimulation in conjunction with thoracic duct draining may be used for removal of tumor cells from the lymphatics.

Amylases↗