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Biomedical subjects

I V Makedonskaia

Publications and source records attributed to I V Makedonskaia.

2 recordsLinked to original sources

[Small thyroid cancer].

Thyroid carcinoma was detected in 1132 of 32500 patients undergoing surgery because of goiter. Small thyroid carcinoma (STC) was found in 245 patients (21.6%) and is divided into the following subgroups: 1) local (focal) microcarcinoma-a focus of a pronounced proliferation, dysplasia and fibrosis up to 1 mm in diameter; 2) invasive dwarf carcinoma of 5 to 15 mm in diameter which is not detected by clinical and instrumental methods; 3) intermediate STC, 1 to 5 mm in diameter. STC had a papillary-follicular structure in 88%, the rest were of a oncocytic and parafollicular structure.

Cell Division↗

[Controversial aspects of verification and classification of thyroid tumors].

20-year experience in the intraoperative study of more than 3000 goiters led the authors to the conclusion that the most correct verification of the pathologic process may be performed only by means of intraoperative stereomorphological and histotopographic examination of the biopsy. In case of nodular hyperplasia of follicular and macropapillary structures the most adequate term is adenomatous goiter. The term borderline thyroid tumor is also suggested although it needs further discussion by both clinicians and morphologists.

Biopsy↗