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Biomedical subjects

I V Kniaz'kin

Publications and source records attributed to I V Kniaz'kin.

12 recordsLinked to original sources
PubMed2003

[Chronic prostatitis: 1) etiology, pathogenesis, modeling, classification].

Apparently, chronic prostatitis subsequently is becoming a disease of not only young and middle-aged men. Its significance in geriatrics is remarkably growing over the past years. Besides, one may note a hurricane-like enlargement of a research literature on this problem. This is linked with countless updated results on prostate morpho-functional peculiarities as well as on causative agents, mechanisms, remodeling, clinical course, and therapeutic approaches on prostatitis. The necessity of summarizing, analysis and discussion of these results is undoubted. Because of enormous material the represented overview of literature has been subdivided in 2 parts, the first of which is given above.

Chronic Disease↗
PubMed2002

[Functional morphology of organotypic culture of spleens from rats of various ages exposed to vilon].

A synthetic dipeptide vilon (Lys-Glu, 20 ng/ml) was added to a cultural medium of explants taken from rats of 3 days, 3 weeks and 2 years of age. The peptide induced morphologic stability of the tissue and activated the regeneration and functional activity of cells. The stronger effect on the explants taken from the old rats suggests that vilon is a candidate for geriatric research and practice.

Adjuvants, Immunologic↗
PubMedDate not supplied

[Spitz nevus (juvenile nevus) of the penile skin].

Compound spindle cell and epithelioid cell nevus (Spitz nevus) at the anterior surface of the penile skin in a 31-year-old patient is described. The histological structure of the tumor is discussed in terms of differential diagnosis.

Adult↗
PubMedDate not supplied

[Use of avelox in treating urogenital infections in men].

We used the drug avelox, a new fluoroquinolone of the fourth generation, in therapy of urogenital infections (caused by chlamydia, mycoplasma, ureaplasma) in men. The test group consisted of 45 men with urethritis, urethroprostatitis given avelox in a single dose of 400 mg/day for 10 days. 18 control patients with urethritis took ofloxacin in a dose of 200 mg twice a day for 10 days. Examination for infection eradication was made 2 weeks and 2 months after the end of the treatment. Eradication of chlamydial infection was achieved in 18 (94.73%) patients, mycoplasma (ones in 23 (80%), ureaplasma--in 29 (86%) patients. Thus, clinical efficiency of avelox may be characterized as very good in chlamydial infection, good in ureaplasma and mycoplasma infections. Side effects occurred only in 5 patients who had short-term transient gastrointestinal disorder. Compared to ofloxacin, avelox is more effective and less toxic.

Anti-Infective Agents↗
PubMedDate not supplied

[Application of the preparation "vitamax" in the complex treatment of chronic prostatitis complicated by sexual dysfunction].

A multivitamin complex Vitamax was given to 65 patients with chronic prostatitis who retained sexual disorders after basic treatment. Mean age of the men was 41 +/- 10 years (25-67 years). The efficacy of the drug was assessed by the data obtained with Male Copulative Function questionnaire. All the patients were found to have mixed sexual dysfunction. Vitamax was taken in a dose 2 capsules a day before a morning meal, a total of 30 capsules a course. After the treatment all the patients improved their copulative function. Thus, Vitamax is an effective drug in sexual dysfunctions related to chronic prostatitis, the efficacy being higher in young men. Side effects were absent.

Adult↗
PubMedDate not supplied

[Use of impase in the therapy of erectile dysfunction].

Efficacy of impasse in therapy of sexual dysfunctions of vascular genesis was studied in 38 male patients aged 35-68 years. The drug was taken for 2 months. The control was conducted with ultrasonic dopplerography. Impasse showed high efficacy in therapy of vascular sexual dysfunctions especially in the group of patients aged 35-50 years with initial values of maximal systolic speed at least 15 cm/s.

5'-Nucleotidase↗