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Biomedical subjects

I Tessman

Publications and source records attributed to I Tessman.

72 records · Page 4Linked to original sources
PubMed1968

Selective stimulation of one of the mechanisms for genetic recombination of bacteriophage S13.

In certain recombination-deficient (Rec(-)) bacterial strains genetic recombination of bacteriophage S13 is reduced, but the existence of some residual recombination has suggested that there is a secondary mechanism of phage recombination that is still functioning. In these Rec(-)strains it is found that there is no stimulation of recombination by irradiation of the parental phage with ultraviolet light, in contrast to the large increase found when irradiated phage particles infect a Rec(+) host. This selective stimulation of phage recombination in the Rec(+) but not in the Rec(-) strains supports the view that the phage uses at least two mechanisms of genetic recombination.

Coliphages↗
PubMed1967

Direction of translation in bacteriophage S13.

Suppressible (amber-type) mutants in gene IIIa of bacteriophage S13 show polarity in reducing the activity of only the neighboring gene IIIb. The polarity implies that the genome is translated in the direction of IIIa to IIIb. From the known homology of the messenger RNA with the single-stranded DNA, the orientation of the DNA with respect to the genetic map can also be inferred.

Chromosome Mapping↗
PubMed1967

Bacteriophage S13: a 7th gene.

Genetic complementation tests of ochre-type suppressible mutants of bacteriophage S13 have revealed a seventh gene. A mutation of this gene has no significant effect on synthesis of the phage replicative form DNA, but like five other phage genes it prevents the appearance of single-stranded DNA. With the new gene, it seems likely that approximately 70 to 100 percent of the phage genes are accounted for.

Coliphages↗