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Biomedical subjects

I Taraba

Publications and source records attributed to I Taraba.

33 records · Page 2Linked to original sources
PubMed1981

[Changes in cellular immunity during peritoneal dialysis].

In 8 patients with chronic peritoneal dialysis before and after 24-hour peritoneal dialysis examinations on the cellular immunity were performed (lymphocyte blast transformation with PHA and Con A, ADCC). There was no difference to the normal findings in healthy control persons. Blast transformation decreased during peritoneal dialysis, no changes were visible with ADCC. Compared with reports in literature concerning regular hemodialysis therapy the state of cellular immunity in chronic peritoneal dialysis seemed to be superior.

Antibody-Dependent Cell Cytotoxicity↗
PubMed1981

Decreased antibody-dependent and spontaneous cell-mediated cytotoxicity in patients with chronic renal failure.

Antibody-dependent and spontaneous lymphocytotoxicity of blood mononuclear cells from 15 patients with chronic renal failure was studied in allogeneic K-562 and xenogeneic chicken erythrocyte test systems. Both antibody-dependent and spontaneous cytotoxic activities were significantly decreased in uremic patients as compared to the corresponding mean values of healthy control persons and non-uremic patients with the same underlying diseases. The addition of autologous serum further reduced the impaired cytotoxic capacity of uremic lymphocytes. Uremic sera also inhibited the antibody-dependent and spontaneous lymphocytotoxicity of healthy individuals.

Adult↗
PubMed1975

Renal function following branch-artery ligation in the canine kidney.

Viable kidney mass has been reduced in dogs by branch-artery ligation combined with uninephrectomy. 1. When viable kidney remnants amount to about 1/4 of the original kidney mass dogs survive in apparent good health with moderate azotaemia; with 1/8 to 1/10 kidney remnants azotaemia is progressive and uraemic death supervenes within some days. 2. Reduction of renal blood flow and of glomerular filtration rate to about one-fourth of their respective control values seems to be compatible with survival; with further reduction death ensues. An inverse and linear relationship between NPN and GFR on a log-log basis has been found. 3. Mean nephron blood flow is equally enhanced in both the more and the less severely infarcted kidneys. On the other hand, mean nephron glomerular filtration is increased when about one half of the kidney is viable, but decreased with more extensive infarction. 4. Mean nephron vascular resistance is diminished; considering the pronounced decrease in Ein, i.e. filtration fraction, predominance of postglomerular vasodilatation is assumed. The formation of non-filtering, actively perfused nephrons is taken into consideration.

Animals↗
PubMed1975

Resistance to acute renal failure afforded by prior renal failure: examination of the role of renal renin content.

In this study, rats recovering from glycerol-induced acute renal failure were found to be protected from mercury-induced nephropathy, and HgCl2 poisoning protected rats from developing myohemoglobinuric renal failure. In view of the widely disparate nature of the renal failure models used, refractoriness appears to relate to an altered sensitivity of the organism itself rather than reflecting resistance to a particular nephropathic challenge. Renal renin content of the rats at the time of rechallenge was normal or high, a finding which contrasts sharply with that of chronically saline-loaded animals which also are refractory to ARF but have a maximally suppressed renal renin content. Renal renin depletion is not essential to the prevention of acute renal failure in the rat.

Acute Kidney Injury↗