Search PubMed⌕ Search

Biomedical subjects

I Takagi

Publications and source records attributed to I Takagi.

At least 73 records · Page 4Linked to original sources
PubMed1986

Hemorrhagic necrosis of pheochromocytoma associated with reversible renal artery stenosis.

An unusual case of pheochromocytoma associated with renal artery stenosis is described. Despite the removal of bilateral adrenal pheochromocytoma, laboratory findings suggested the presence of residual pheochromocytoma and abdominal aortography revealed more pronounced stenosis of the right renal artery. Two months later, the undetected residual pheochromocytoma underwent hemorrhagic necrosis with acute cessation of catecholamine release. Thereafter, the patient's blood pressure decreased to a normal level with marked improvement in hypertensive symptoms. No remaining stenosis was demonstrated on follow up renal angiography. Our case suggests that constant local secretion of catecholamines may be responsible for the development of renal artery stenosis.

Adolescent↗
PubMed1985

Relationship between the radiologic features of esophageal cancer and the local control by radiation therapy.

In order to predict the possibility of local control of esophageal cancer by radiation therapy, the relationship between the x-ray findings before and after irradiation and the histologic radiation effect obtained from the surgically resected esophagus was analyzed in 130 cases irradiated preoperatively during the period 1971 through 1980. In the superficial or proliferative type in x-ray image before treatment, the local control was obtained in 46.5% of the cases with the dose of 40 Gy, whereas in the ulcerative or infiltrative type, in 21.8%. The barium examination performed after irradiation was more useful to evaluate the radiation effect than that before treatment. In cases with a marked radiation effect after irradiation, the frequency of local control reached 76.9%. On the other hand, the local control remained 11.9% in cases with no or poor radiation effect. The results obtained by the preoperatively irradiated cases were applied to the analysis of 119 cases irradiated radically during the period 1965 to 1980. Almost the same results were also acquired in radically irradiated cases. The degree of radiologic and histologic radiation effect on the primary tumor was closely related to the long-term survival rate of the patient.

Adult↗
PubMed1985

Nonfunctioning adrenocortical carcinoma in a young girl.

A 9 year old Japanese girl was admitted complaining of left hypochondrial pain and a large upper left abdominal tumor. There were no clinical or laboratory signs of hormonal abnormality. Intravenous pyelography showed marked compression and deformity of the kidney by a tumor. This tumor was excised together with the left kidney. The pathological diagnosis was adrenocortical carcinoma. Postoperatively, the child was given neither irradiation nor chemotherapy. Twenty-one months after the surgery, there was a hepatic metastasis, and she died 40 months after surgery from a combination of hepatic metastases and local tumor recurrence.

Adrenal Cortex Hormones↗
PubMed1984

Interaction of fibrinolytic activity between the tracheobronchial secretion and circulating blood of rats.

In order to clarify the origin and release mechanism of plasminogen activator in the tracheobronchial secretion of rats, electrophoretic analysis of the secretion and studies on the effects of certain vasoactive drugs on the activator activity in the secretion were carried out. From the results of electrophoretic analysis of the tracheobronchial secretion in non-treated rats, protease inhibitor composed of glycoprotein was not contained in the secretion in contrast to the circulating blood, but a protein of low molecular weight like albumin in the circulating blood was contained in the secretion. Furthermore, after injection of noradrenalin, the blood pressure was temporarily elevated and the fibrinolytic activity of the euglobulin fraction in the circulatory blood was also increased. Subsequent to this elevation of fibrinolytic activity in the circulating blood, the fibrinolytic activity in the tracheobronchial secretion increased. Based on these results, it is suggested that the increase of fibrinolytic activity in the circulating blood was due to increased release of plasminogen activator from the vascular wall, and the increased fibrinolytic activity of the tracheobronchial secretion was caused by a consequent increased transudation of plasminogen activator from the circulating blood into the tracheobronchial lumen.

Animals↗
PubMed1984

A morphological study of the ultimobranchial body in the grass parakeet.

As parafollicular cells can be stained by Grimelius' silver impregnation and by lead-hematoxylin, the ultimobranchial body cells, homologous to them, seem to also react positively to these methods. In the present study of the ultimobranchial body of the grass parakeet, mirror-image sections were stained by both methods and compared. While about 50% of the cells reacted positively to both Grimelius' silver impregnation and lead-hematoxylin staining, only about 20% were positive to the former and about 30% were positive to the latter only. This result indicating heterogeneity among the cells of the ultimobranchial body of the grass parakeet suggests a possible occurrence of cells secreting substances other than calcitonin.

Animals↗
PubMed1984

The role of fibrinolytic enzymes in inflammation and paranasal mucous membrane.

The distribution and role of tissue plasminogen activator (TA) and proactivator (PA) in various diseases of the nasal and paranasal cavity were investigated. The stronger the inflammatory and proliferative response of the paranasal mucous membrane, the weaker was the fibrinolytic activity of TA. The fibrinolytic activity of PA tended to be stronger than TA activity. It is considered that PA may play an important role in inflammatory enlargement and proliferation of the paranasal mucous membrane, but does not play an important role in carcinogenic enlargement and proliferation of the nasal and paranasal mucous membrane.

Enzyme Precursors↗