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Biomedical subjects

I Takada

Publications and source records attributed to I Takada.

At least 55 records · Page 3Linked to original sources

[A cured case of hypertensive intracerebellar hematoma (author's transl)].

A case of hypertensive intracerebellar hematoma surgically treated and cured was reported. The 41-year-old male had two cerebrovascular attacks with headache and vomiting followed by left hemiparesis. Drowsiness and dysarthria appeared the next day. The patient was admitted to a hospital, where right facial palsy, loss of right gag reflex and paralytic hemiplegia on the left side were noted. On the 7th day, the patient's consciousness became clear byt the other neurological evidences did not change. On the 14th day, bradycardia and central hyperventilation appeared and he became drowsy again. The patient was transferred to the authors' clinic. When the patient was admitted, he showed typical cerebellar signs such as nystagmus, ataxia, and slurring speech with pyramidal sign on left side and cranial nerves paralysis on right side, and also showed the changes of vital signs as a medullary syndrome in the late stage of the course. The vertebral angiogram revealed a space taking process in the right cerebellar hemisphere. The old blood (30g) was removed by suboccipital craniectomy. The hematoma cavity had a communication with the IVth ventricle through a small perforation in the medial wall of the hematoma. Spontaneour intracerebellar hematoma including of hypertensive origin is not rare in the reports of autopsy but surgically treated case has only rarely been reported. The main reason of few survivals should be in its fulminate course.

Adult↗

[On the phenomena of extravasation of contrast media in cerebral angiogram of the case of hypertensive intracerebral hematoma and their clinical significance-analysis of 14 cases (author's transl)]?

Since Westerburg (1966) reported a case of hypertensive intracerebral hemorrhage who showed extravasation of contrast media on the cerebral angiogram, only 21 cases demonstrated extravasation of contrast media were reported by several authors. The author experienced 14 cases of hypertensive intracerebral hemorrhage whose cerebral angiogram showed extravasation of contrast media. These 14 cases occupied 21.1% of 58 cases whom cerebral angiographies were performed within 24 hours after the stroke. 6 out of 14 cases were cured by evacuation of the hematoma surgically. These 14 cases were dividied into three types by the shape of extravasation of contrast media as followed: Type I showed widespread leakage of contrast media. Type II showed sash-like leakage of contrast media surrounded by diffuse thin shadow and Type III showed small spotlike leakage of contrast media. These three types indicated the arterial bleeding stage, the stage of accerelated arterial wall permeability and the subsquent venous bleeding respectively. The author concluded that these extravasation of contrast media not only demonstrated the bleeding artery but also indicated the process of the hematoma formation in each case.

Adult↗

Effect of exogenous catecholamines in the amygdala of a 'rage' cat.

Minute amounts of epinephrine or norepinephrine alter the behavior of 'rage' cats (prepared by ventromedial hypothalamotomy) when these substances are focally instilled into both amygdalae via chronic brain cannulae capped with a silastic membrane. Hyperactive defense reactions are replaced by lethargy and placidity. Similar injections of epinephrine or norepinephrine into the amygdalae of normally placid cats who had not been subjected to ventromedial hypothalamotomy did not appreciably alter their behavior.

Amygdala↗

Effects of somatostatin deficiency on cell distribution within the Langerhans islets.

Insulin, glucagon and somatostatin (SLI) in the pancreas and the gastrointestinal tissue of rats were measured following a high (300 mg/kg) or low (150 mg/kg) dose of cysteamine, given intermittently for 14 days. In addition, the effect of prolonged cysteamine-induced depletion of pancreatic SLI upon the cell distribution within the Langerhans islets was compared with that of chronic insulin-deficient rats produced by streptozotocin. The high or low dose of cysteamine reduced pancreatic SLI to 8.3% and gastrointestinal SLI to 5.6% of control levels without duodenal ulcer. The high dose of cysteamine also reduced pancreatic insulin to 37% of controls without hyperglycemia. No change in the glucagon concentration was observed. In SLI-deficient rats, distribution of A and B cells was similar to that of controls, even though D cells were rarely seen. In insulin-deficient rats, however, the number of A and D cells per islet area increased with a concomitant decrease in B cells. Intermittent administration of a low dose of cysteamine, thus, appears to be useful to produce a chronic SLI-deficient rat. However, a high dose of cysteamine is not a specific depletor of pancreatic SLI. Although insulin may be important to maintain normal cell distribution within the islets, pancreatic SLI may not have such a role.

Animals↗