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Biomedical subjects

I Sherwin

Publications and source records attributed to I Sherwin.

12 recordsLinked to original sources
PubMed1986

Fingerprint pattern differences in early- and late-onset primary degenerative dementia.

The frequency distribution of major fingerprint patterns (ulnar or radial loops, arches, and whorls) was studied in 47 men with early-onset (aged, less than or equal to 64 years), 35 men with late-onset primary degenerative dementia (aged, greater than or equal to 65 years), and 100 control subjects (aged, 29 to 78 years). Patients with an early, but not those with a late, onset of dementia had significantly more ulnar loops than the control group. This finding, along with other data, is interpreted as indicating that there may be a biologic basis for distinguishing these two forms of dementia.

Aged↗
PubMed1978

Interictal--ictal transition in the feline penicillin epileptogenic focus.

A study was undertaken to examine those EEG features which characterize interictal--ictal (II--I) transitions in the feline penicillin focus. The study describes certain complex changes in spike frequency and their statistical analysis, which appear to have predictive value in signaling II--I transitions. The significance of these data with respect to the conflicting results of other studies and their possible application to clinical epilepsy are discussed.

Animals↗
PubMed1978

"Organic brain syndromes": an empirical study and critical review.

The authors found that all but 3 of 80 randomly chosen patients in a Veterans Administration hospital who had been given a primary nonspecific neuropsychiatric diagnosis (organic brain syndrome, organic psychosis, chronic brain syndrome, etc.) could be assigned to specific diagnostic categories. Diagnosis was based on chart review and thorough neurological and clinical evaluation. Senile and alcoholic dementia and Korsakoff's syndrome were seen most often, and 15% of the patients were diagnosed as having functional disorders of the mental state. The authors review the organic brain syndrome diagnosis in light of this and other evidence. They believe that fractionation into more specific diagnoses is essential to further understanding of this group of diseases. Use of the general term can result in inappropriate or no treatment; further, it hampers essential psychological, pharmacological, and biomedical research on these disorders.

Adult↗