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Biomedical subjects

I Schréter

Publications and source records attributed to I Schréter.

8 recordsLinked to original sources

Detection of SEN virus in the general population and different risk groups in Slovakia.

Sera of 426 adult persons were examined to assess the prevalence of SEN virus (SENV) infection in Slovakia and to determine the importance of different risk factors for parenteral transmission. SENV prevalence was determined by the PCR method using primers of SENV-D and SENV-H strains. Positive results were found in 10 of 37 patients with acute hepatitis of unknown etiology, 7 of 38 with acute hepatitis B, 17 of 44 with chronic hepatitis B, 29 of 102 with chronic hepatitis C, 36 of 72 hemodialysis patients, 2 of 33 health care workers and 24 of 100 persons from the control group. The highest prevalence of SENV was among hemodialysis patients, significantly higher than in the groups of health care workers, acute hepatitis B and controls. The lowest prevalence was in health care workers group, significantly lower also in comparison with groups of chronic hepatitis B and C. Among the possible risk factors of virus transmission the average duration of hemodialysis (1.15 vs. 0.50 years), number of surgeries (1.60 vs. 1.10) and transfusions (1.34 vs. 0.94) showed notable differences in terms of SENV infection. Bilirubin and aminotransferase levels did not differ between SENV-positive and -negative groups. No pathogenetic role of SEN virus in liver injury was confirmed.

Adult↗

[Travel during pregnancy and possibilities of vaccination].

Pregnancy presents special medical problem where we need to take into account travel risks regarding pregnant women and the health limits as a consequence of pregnancy. It is also important to consider the fact that active prevention and treatment approaches are to a large degree limited by the pregnancy. The most optimal period for travelling is the second trimester. In most cases, the potential risk of administering the vaccine is theoretical and not based on clinical evidence. Pregnancy presents a special problem regarding many aspects of immunization: benefit of vaccination, potential disease risk to the mother and fetus and safety of vaccine to mother and fetus itself. In general, pregnant patients should avoid live vaccines. Vaccination with inactivated, conjugated, polysacahecride vaccines and toxoids is possible. The first trimester of pregnancy is the most vulnerable period because of theoretical risk of harmful effects to the fetus.

Female↗

["Economy class syndrome"--common risk of travelers?].

Economy class syndrome is the term for cases of venous thrombosis/, that start in connection with travelling for long distance. Syndrome occurs most frequently in economy class of flying. Because of crowded uncomfortable conditions by sitting, without movement during longer journey by plane can cause thrombosis, especially for patients with risk factors. Sequentially thrombembolism can occur. The most often risk factors are age, obesity, hormonal contraception, previous thrombosis in case history, smoking, immobilization, diabetes mellitus, diseases of vascular system and kidneys, and others.

Aerospace Medicine↗

[Liver biopsy in Slovakia].

INTRODUCTION: Liver biopsy is the most specific diagnostic modality in hepatology, but information about its application in Slovakia is rather obscure. METHODS: The authors performed a correspondence study with the aim to find out how many biopsy examinations has been done in Slovakia in 2001, for which indications, what kind of techniques have been applied and which small or great complications were encountered. RESULTS: It was established that in the year 2001, 400 biopsies for diffuse liver diseases were performed. There were 296 percutaneous biopsies, 82 laparoscopic biopsies and 22 trans-jugular biopsies forming the survey. Acute viral hepatitis was the most frequent indication, whereas non-alcohol steatohepatitis was a rare indication in spite of the high prevalence. The frequency of great complications was 0.00025%. No death associated with this procedure was reported. CONCLUSION: Liver biopsy has been done in Slovakia in indications, ways and with the frequency of complications, which were comparable with data from literature.

Biopsy↗

[Occurrence of acute infectious diarrhea during the lunar phases].

A chronobiometric analysis of 753 cases of acute infectious diarrhoea in adults in 1981-1990 in Kosice confirmed to a surprising extent recently reached conclusions of an investigation made by authors from Bratislava. The Kosice group comprised 352 cases of bacillary dysentery, 305 patients with salmonellosis, 72 with campylobacteriosis and 24 with yersiniosis. Statistically significantly fewer patients (p < 0.0001) were hospitalized during full moon, moon quarterly and new moon. In the intervals there were periods with a short-term increase of the daily admissions by cca 25%. This 7.38-day periodicity cannot be explained by the influence of the social 7-day week, as during observations extending over several years this rhythm is eliminated by a gradual shift across different phases of the moon. The authors did not find similar reports in the literature. For explanation, not only the organism of the host (variable immunity?) but also the infectious agent must be taken into account. More profound understanding of the mechanism may open the road to practical application of the described lunar relationship. Its knowledge can help already now to improve the organization of the health service.

Acute Disease↗

[The incidence and clinical picture of hemorrhagic fever with renal syndrome in East Slovakia: the eastern and western type].

Hemorrhagic Fever with renal syndrome (HFRS) is endemic in East Slovakia. The paper presents the clinical picture of 4 serologically confirmed cases. Two of the 4 patients had serological evidence of recent Hantaan virus infection. Positive immunofluorescent reactions with Puumala virus (CG 18-20) were detected in the sera of the other two patients. The obtained results suggest the circulation of two serotypes of HFRS in Slovakia.

Adolescent↗

[Löffler's endocarditis].

The authors describe Loeffler's endocarditis and the treatment of this clinical entity. Among diagnostic methods which drew attention to a cardiac affection associated with eosinophilia, non-invasive examination methods were of decisive importance. They comprised conventional electrocardiographic examination, X-ray of the chest and two-dimensional echocardiography.

Endocarditis↗