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Biomedical subjects

I Sauer

Publications and source records attributed to I Sauer.

79 records · Page 5Linked to original sources
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[The use of Ergocomb in symptoms of cerebrovascular insufficiency].

Using a test design of subjective, clinical and psychometric parameters, Ergocomb was tested, in a double-blind trial, on fifty-five patients with cerebrovascular insufficiency. The test results, which are in agreement with those reported in the literature, show a substantial improvement of various subjective and objective criteria. Therefore, Ergocomb, in the form of swallowable tablets, is considered suitable for application to patients with senile cerebral insufficiency, the recommended dosage being 3 x 1 mg.

Aged↗
PubMedDate not supplied

[Systolic time interval as a means of evaluating the cardiac functional capacity in patients with and without heart insufficiency].

Determining the systolic time intervals in a non-invasive method which is easy to apply and inexpensive, and it can be repeated as many times as necessary. The patient is subjected to low psychic stress so that even elderly and sick patients may undergo it. The STI method may be applied to case control and the observation of the development of a disease following pharmacological treatment. The method makes it possible to differentiate between healthy persons and patients suffering from cardiac insufficiency, and concealed insufficiencies of the cardiac circulation may be detected. The STI interpretation must take into account those factors which have an effect on the STI length. The results can be considerably upgraded through the use of certain indices, PI being the main one. The PI index is of particular value if the effect of the treatment by glycoside medication is to be observed.

Aged↗
PubMedDate not supplied

Selected metabolic results of the Leipzig gerontological longitudinal study.

The results of the longitudinal study show a gradual development of the overweight of young obese women. The decrease of weight in middle aged obese women is likely to be influenced by additional therapeutic measures by the physicians. It is interesting to note that men and women of normal weight do not develop overweight over a ten-years-span. Serum cholesterol increased in all age and weight groups within a ten-years-interval. The changes of the shares of total fatty acids were especially characterized by the decrease of palmitic acid and the increase of linoleic acid in the ten-years-interval. However age, weight and sex differences were present. The increase of uric acid level occurred with all test persons independent of sex. With test persons above 45 years a significant sex difference was noticed.

Adult↗
PubMedDate not supplied

[Changes in parameters of lipid metabolism and anti-oxidative potentials in elderly hyperlipoproteinemic patients treated with omega-3 fatty acids].

Omega-3-fatty acids play a protective role in the prevention of CHD, however, they can have a negative influence on LDL-oxidation and aging processes by the formation of peroxides. In 56 patients with HLP (40 with mixed HLP and hypertriglyceridemia, respectively, and 16 with hypercholesterolemia) changes in the lipid state and in the parameters of the antioxidative potential before and after a 4-week-olive-oil phase and after 8, 20, and 32 weeks intakes of salmon-oil capsules were determined. The treatment with salmon-oil capsules were determined. The treatment with salmon oil led to a decrease of triglycerides in patients with hypertriglyceridemia and to an increase of cholesterol in hypercholesterolemia. Following the increase of malondialdehyde as measure of the lipid peroxidation a substitution of antioxidants, like vitamin E and vitamin C, seems to be useful. Further investigations are necessary before wide use of fish-oil capsules, not least to avoid side-effects.

Adult↗
PubMedDate not supplied

[Biological age in patients with progressive scleroderma].

In 25 patients (10 male, 15 female) with systemic sclerosis aged between 28 and 79 years the biological age was determined. Alterations in the sense of "premature aging" were observed in the mean and developed stronger in male patients. They have to be counted in a greater part on the real process of disease. Compared to a healthy reference group, the expected diminishing of hand grip strength and tendon extensibility, vital capacity and partial oxygen pressure in the arteries could be confirmed. The latter correlated to an increase in rest pulse. Auditory acuity and the condition of the teeth were also reduced. Beyond that, noteworthy differences in psychological and social parameters not presumed at the beginning point to a decrease in social activities and to psychic changes. They underline the necessity of psychological counseling of the patients.

Activities of Daily Living↗
PubMedDate not supplied

[Sepsis and SIRS (systemic inflammatory response syndrome) in the puerperium--pathogenesis and clinical management].

PURPOSE: We report about 5 cases of "puerperal sepsis" to elucidate the clinical significance and resulting therapeutic management of Sepsis, SIRS (Systemic inflammatory response syndrome) and MODS (Multiple organ dysfunction syndrome), whose definitions were introduced at the Consensus Conference of the American College of Chest Physicians/Society of Critical Care Medicine in 1992. RESULTS: All patients had documented endomyometritis, 3 of them in combination with ovarian vein thrombosis. None of the patients responded adequately to conservative treatment with antibiotics and intravenously applied Heparin. After 12 to 72 hours, because of clinical deterioration, all women underwent laparotomy with hysterectomy combined with an ovarectomy in 3 cases. Although the inflammatory "septic" source was removed by the surgical intervention, the clinical condition of 3 of the patients further deteriorated; they were suffering from SIRS, and 2 developed MODS. Symptoms of MODS were DIC, hypotension, kidney failure and encephalopathy. CONCLUSIONS: Our results support the theory that infection or trauma may initiate an endogenous inflammatory response which could progress to MODS even after removal of the initial source. Our findings, however, do not support the view that septic endomyometritis and postpartum ovarian vein thrombosis should be treated nonsurgically, because the clinical course in our patients was less complicated the earlier the surgical intervention was initiated.

Adult↗