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Biomedical subjects

I Sato

Publications and source records attributed to I Sato.

At least 415 records · Page 23Linked to original sources
PubMed1981

Age-related changes of cardiac control function in man. With special reference to heart rate control at rest and during exercise.

Heart rate control function at rest and during exercise in regard to age were studied in 39 healthy male volunteers (age 15 to 75). The heart rate control function during exercise was evaluated by using system analysis of heart rate response to two-step exercises (66 and 84 steps/min). No age-related changes were found in the resting heart rate at supine position or in oxygen consumption at upright rest and during the exercises. However, the mean value and the magnitude of variation of the heart rate at upright rest and the difference of heart rate at upright and supine rest showed significant negative correlations with age. As age advanced, the transfer function of the system during exercise exhibited characteristic changes depending on the frequency ranges. These findings suggest that activity of both sympathetic and parasympathetic nervous systems were depressed at rest, and that contributions of sympathetic and vagal nervous systems during exercise are more enhanced and more depressed, respectively, in older subjects than in younger subjects.

Adolescent↗
PubMed1980

Autonomic nervous control of the heart in exercising man.

Effects of pharmacological denervation with propranolol (0.2 mg.kg-1) and/or atropine (0.04 mg.kg-1) on the control system of heart rate during exercise were studied using a frequency domain analysis, to evaluate the cardiac control function of autonomic nervous systems in man. Propranolol decreased the gain of the system in low frequency range and increased the gain slightly in middle and high frequency ranges. The phase angle of the system was advanced over the whole frequency range observed. Atropine decreased and delayed the gain and phase angle, respectively, especially in high frequency range. The combined administration of blockades significantly decreased the gain and delayed the phase angle in the whole and high frequency ranges, respectively. These findings suggest that sympathetic and parasympathetic nervous systems act nearly independently in controlling heart rate during exercise; that they act in different manners; and that the characteristics of the systems can feasibly be used to estimate clinically the cardiac control function of autonomic nerves in man.

Adult↗
PubMed1980

Guillain-Barré syndrome presenting with signs of ophthalmoplegia.

Two cases of Guillain-Barré syndrome (GBS) presenting with signs of ophthalmoplegia were reported. One showed unilateral internal ophthalmoplegia without external ophthalmoplegia, and the other displayed partial external ophthalmoplegia with sluggish pupillary response to light. It is important to keep in mind the possibility of GBS with acute onset of internal and/or external ophthalmoplegias.

Child↗