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Biomedical subjects

I S Jain

Publications and source records attributed to I S Jain.

At least 19 recordsLinked to original sources
PubMed1991

Visual prognosis in central serous choroidopathy: residual Amsler grid changes.

To assess residual changes on Amsler grid charting in central serous choroidopathy, 30 patients (34 eyes) with the disorder were followed from the time of onset of symptoms to the time of resolution of the disease. A total of 28 eyes, including all 3 with an acuity of 6/6 or better, had Amsler grid changes at presentation, compared with 13 eyes at the last follow-up visit. Significantly more patients with a disease duration of more than 8 weeks than those whose disease lasted 8 weeks or less had residual changes (p less than 0.01). Overall, 41% of the eyes had a final acuity of less than 6/6 or a residual change or both.

Adult↗
PubMed1990

Atrophy of myelinated nerve fibers in pituitary adenoma.

A one-eyed patient was referred as a case of amblyopia secondary to myelinated retinal nerve fibers. Investigations revealed a pituitary adenoma. Following surgical ablation of the tumor, reduction in the myelination became evident. We report this rare occurrence in a case of pituitary tumor with photographic documentation for the first time.

Adenoma↗
PubMed1989

Uremic optic neuropathy.

A rare case of documented reversible bilateral optic neuropathy as the presenting manifestation of chronic renal failure is discussed. Repeated hemodialysis in the early stages of the disorder was useful for recovery of vision.

Adult↗
PubMed1988

Ocular manifestations of Wegener's granulomatosis in north India.

Evidence of ocular involvement was found in seven of eleven patients with histologically confirmed Wegener's granulomatosis. Pain (7/7), redness (6/7), scleritis (5/7), reduced visual acuity (5/7), episcleritis (5/7), uveitis (3/7), proptosis, sclerokeratitis and conjunctivitis (2/7) each were the major ophthalmological features. One patient each had bilateral corneoscleral ulcers, eyelid infiltration, scleromalacia perforans and epiphora. Corneal, scleral and uveal tract involvement was observed more frequently than has been described in the literature. These complications responded favourably to treatment with cyclophosphamide and corticosteroids. Treatment was delayed as most of these patients were diagnosed, initially, to be suffering from tuberculosis.

Adolescent↗
PubMed1987

Ocular and orbital metastasis from systemic malignancies.

One hundred and seventy adult patients and one hundred and forty-eight children with systemic malignancies were examined for ocular and/or orbital metastases. Thirty-six patients (11.3%) had intraocular and/or orbital metastasis. Twenty-nine of the 36 patients (80.5%) had orbital metastasis, five patients (13.9%) had intraocular and two patients (5.5%) had intraocular and orbital metastasis. The commonest malignancy producing ocular metastasis was carcinoma breast in females and carcinoma bronchus in males. Eight of the 17 children had orbital deposits from leukaemia (47%) and six from neuroblastoma (35%). One child had uveal infiltration from acute lymphatic leukaemia. Ophthalmic metastasis were treated by external irradiation and/or combination chemotherapy whenever possible. The mean survival was five months for intraocular metastasis and 15.6 months for the orbital metastasis in adults. Prognosis was very poor in children.

Adult↗
PubMed1987

Adenocarcinoma of ciliary epithelium in a young boy.

A rare case of adenocarcinoma of the ciliary epithelium is reported in a 17-year-old boy who had been mistakenly operated on for secondary glaucoma. There was extraocular extension and presentation as a fungating mass.

Adenocarcinoma↗
PubMed1986

Nevus of Ota associated with neurofibromatosis.

An association of neurofibromatosis with nevus of Ota is described in a young woman. The association of these disorders demonstrates a true proliferative process of neuroectodermal tissue.

Adolescent↗
PubMed1986

The use of intralesional steroids in the treatment of chalazion.

Intralesional injection of triamcinolone acetonide 5 mg/mL suspension was used in the treatment of 110 cases of chalazion; 92.3% of the cases resolved completely with one to three injections, irrespective of the duration and consistency of the chalazion. Recurrence and yellow deposits were seen at the site of injection in a minority of patients.

Cysts↗
PubMed1985

Visual prognosis in pituitary tumors.

In a study of 15 patients with pituitary adenoma, preoperative and postoperative evaluation of peripapillary nerve fibers by red-free fundus examination showed that a good correlation exists between preoperative loss of peripapillary nerve fibers and the final visual outcome.

Adenoma↗
PubMed1984

Enterovirus 70 acute hemorrhagic conjunctivitis--sporadic cases.

Acute hemorrhagic conjunctivitis (AHC) has been reported in epidemics. This is a report of 29 sporadic cases of AHC recorded over a period of two years after the 1981 epidemic in and around Chandigarh. A rapid and simple immunofluorescence test was developed and standardized in our Institute for the diagnosis of AHC. It was used for epidemiological monitoring of cases and to establish the diagnosis in suspected cases of AHC reporting after the epidemic. The clinical picture of epidemic and sporadic cases is compared.

Acute Disease↗
PubMed1984

Cilioretinal artery occlusion: a case report.

A young man had an occlusion of the cilioretinal artery. Recirculation in the vessel was established within 48 hours. The retinal damage has been permanent with no improvement in visual acuity. Fluorescein angiography during the stages of occlusion and established recirculation have been described. Vascular spasm of a short posterior ciliary artery due to smoking is the likely causal factor. The site of obstruction and the hemodynamic factors have been discussed.

Adult↗
PubMed1983

Immunofluorescence test for the epidemiological monitoring of acute haemorrhagic conjunctivitis cases.

An epidemic of acute haemorrhagic conjunctivitis (AHC) occurred in and around Chandigarh, north India, during June, July and August 1981. Considering the difficulty of virus isolation, the indirect immunofluorescence test was used for the demonstration of virus-specific antigen in the cytoplasm of exfoliated conjunctival cells, using reference antisera. The epidemic appeared to be primarily due to enterovirus type 70. The method was found suitable for the rapid diagnosis of AHC cases and for detecting subclinical infection among healthy subjects and convalescent carriers. During follow-up, it was observed that some of the AHC cases were shedding virus-infected conjunctival cells for a prolonged period, even after clinical recovery and during convalescence, before they became free from virus. In the absence of virus isolation, this method can be considered as suitable for the epidemiological monitoring of AHC.

Acute Disease↗
PubMed1983

Fuchs' heterochromic cyclitis: some observations on clinical picture and on cataract surgery.

In a study of 33 patients of heterochromic cyclitis, some unusual clinical features were observed. In many cases the iris was feltlike, month eaten, and associated with gelatinous nodules at the pupillary border or over the surface of iris stroma. An association of pseudoexfoliation of the lens capsule with bilateral heterochromic cyclitis was noted. Twenty-one eyes were subjected to cataract surgery. Hyphema (23.6%) and phacoanaphylactic uveitis (9.5%) were the main postoperative complications.

Adolescent↗