[The pharmacokinetics of recombinant human erythropoietin].
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Biomedical subjects
Publications and source records attributed to I S Iarmolinskiĭ.
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The authors conducted a clinical study of the hypothesis of interleukin-1 regarded as one of the most important topics in the problem of biocompatibility of dialytic membranes. Hemodialyses (HD) were performed using different cellulose and synthetic membranes. During HD research was made into the kinetics of monocytes and lymphocytes, monocytic activation expressed by a stimulation index, and the deposition of blood elements on the membranes of parallel membrane dialysers. All types of cellulose membranes were characterized by acute dialytic monocytopenia. Synthetic membranes produced no considerable monocytopenia. No convincing data on the dependence of the monocytic stimulation effect on membrane material were obtained. Possible mechanisms of monocytic activation during HD were discussed.
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The authors report their experience with 71 procedures of constructing a subcutaneous arterio-venous fistula in 56 patients suffering chronic venous insufficiency. Surgical technic of 7 various modifications in producing arterio-venous fistulas on the upper and lower extremities is described and the methods of the postoperative management, as well. An analysis of main complications is given. By means of arterio-venous fistulas over 700 seances of hemodialysis were performed.
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