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Biomedical subjects

I Rzewnicki

Publications and source records attributed to I Rzewnicki.

24 records · Page 2Linked to original sources

[The behaviour of serotonin in blood, the activity of monoaminooxidase in serum and of 5-hydroxyindoloacetic acid in twenty-four hour urine in patients with viral hepatitis (author's transl)].

The level of serotonin in blood, the activity of MAO in serum and the value of 5-HIAA in 24 hour urine were estimated in 76 patients with viral hepatitis divided according to clinical parameters into three groups (mild, mild to severe and severe clinical course). A statistically significant increase of serotonin level in blood compared with the healthy control group was found. Highest values were observed in patients with the severe form of viral hepatitis. Decreased values of 5-HIAA in 24 hour urine in the early course of the disease showed a tendency to increase in later examinations. The activity of MAO in serum was significantly lowered in all clinical forms of viral hepatitis.

Adult↗

[Dynamics of immunologic reactivity in the acute phase of virus hepatitis B].

In 15 patients with acute icteric viral hepatitis B the immunological reactivity was tested. The examinations were performed on the 1st, 7th, and 14th day of hospitalization. They consisted of the determination of the HBsAg and its antibodies in the serum, of the percentage of the B- and T-lymphocytes, of the lymphocyte transformation test under the influence of phytohaemagglutinin, of the lymphocyte migration inhibitory test when the HBsAg is present as well as of the determination of the IgG, IgA and the IgM-level. A decreased percentage of the T-lymphocytes, a decreased blastic transformation and an inhibition of the lymphocyte migration was proved. After a transient increase in the first and second examination the IgG-level returned to the normal in the third examination, whereas the IgM-level increased. Finally dynamics and importance of the cellular reactivity in the pathogenesis of viral hepatitis B are discussed.

Acute Disease↗